NASDAQ$ARWR

Arrowhead Pharmaceuticals Inc · Q2 2025 earnings

Q2 2025 earnings · · After market close · Investor relations

Briefing

Arrowhead Pharmaceuticals reported fiscal Q2 2025 revenue of $543M with net income of $370M and diluted EPS of $2.75 on Sarepta collaboration revenue.

Revenue of $542.7 million was recognized from the Sarepta collaboration agreement, including upfront and milestone-related amounts. Net income attributable to Arrowhead was $370.4 million; diluted EPS was $2.75 versus a loss a year ago. Deferred revenue and R&D obligations remain for ongoing collaboration programs.

  • Fiscal Q2 revenue $543M from Sarepta collaboration.
  • Net income $370M; diluted EPS $2.75.
  • Deferred revenue $43M on remaining performance obligations.
  • Pipeline R&D spend continues on partnered programs.

Headline financials

Total Revenue

$543M

Previous: $0.00
EPS (adj)

$2.75

Previous: -$1.02+369.6%
Capital Expenditures

-$12.8M

Previous: -$103M+87.5%
Net Income

$370M

Previous: -$125M+395.6%
Operating Income

$381M

Previous: -$126M+402.1%

Revenue & EPS history

Arrowhead Pharmaceuticals · Revenue · Quarterly

$543M

Q2 2025
Beat estimate in 5 of 15 quarters(33%)
ActualEstimate

Forward guidance

Biotech outlook emphasizes collaboration milestones, R&D spend, and cash runway.

Tailwinds

  • Partnership revenue and milestone potential.
  • Clinical progress on lead degraders or immuno-oncology assets.

Headwinds

  • Operating losses and dilution risk.
  • Trial and regulatory execution uncertainty.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2025

Historical avgQ2 2025

+0.0%

Avg return

Earnings day

+4.2%

Avg return

5 days after

+10.8%

Avg return

30 days after

38%

24 / 64 earnings

Positive

+39.2%

Q4 2024

Best reaction

-26.7%

Q4 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2026+1.6%+0.1%-6.1%
Q1 2026-0.2%-4.8%-7.5%
Q4 2025+23.2%+20.2%+49.9%
Q2 2025+9.4%+12.5%+16.1%
Q1 2025-5.2%+0.2%-24.3%
Q4 2024+39.2%+38.5%+3.9%
Q3 2024-6.4%-8.6%-11.1%
Q2 2024-12.5%-9.2%-5.2%
Q1 2024-1.2%+1.7%+3.7%
Q4 2023-26.7%-13.8%+5.8%
Q3 2023-13.1%-8.8%-7.7%
Q2 2023+12.5%+15.8%-2.9%
Q1 2023-8.5%-9.9%-19.3%
Q4 2022+1.7%+15.0%+27.3%
Q3 2022+3.6%+2.5%-11.1%
Q2 2022-11.5%-3.3%-0.7%
Q1 2022-11.1%-5.4%-22.1%
Q4 2021-0.3%+1.3%-1.8%
Q3 2021-2.0%-7.4%+2.2%
Q2 2021-5.4%-5.5%+3.2%
Q1 2021+12.6%+11.8%-14.1%
Q4 2020-12.2%-8.4%+24.1%
Q3 2020-7.0%-8.5%-18.3%
Q2 2020-0.3%+5.0%-0.5%
Q1 2020-6.4%-2.4%-23.9%
Q4 2019+37.6%+48.4%+31.2%
Q3 2019-2.1%-0.2%+17.6%
Q2 2019+8.0%+0.1%+50.2%
Q1 2019+13.2%+25.4%+33.0%
Q4 2018+11.2%+4.8%+9.8%
Q3 2018+13.2%+18.6%+36.2%
Q2 2018+15.8%+27.2%+33.5%
Q1 2018-6.2%-3.4%+30.9%
Q4 2017-3.1%-10.5%+43.6%
Q3 2017+8.9%+13.6%+69.2%
Q2 2017+13.5%+6.4%+3.8%
Q1 2017+3.2%+3.7%+12.1%
Q4 2016+0.0%-1.6%+62.2%
Q3 2016-1.2%+1.0%+29.7%
Q2 2016-3.1%
Q1 2016-0.9%
Q4 2015-1.1%
Q3 2015+12.1%
Q2 2015-10.9%
Q1 2015-1.1%
Q4 2014-6.2%
Q3 2014+1.2%
Q2 2014-10.7%
Q1 2014-2.6%
Q4 2013+7.3%
Q3 2013+2.5%
Q2 2013+10.2%
Q1 2013-1.8%
Q4 2012-7.2%
Q3 2012-16.8%
Q2 2012-4.5%
Q1 2012-1.4%
Q4 2011+0.5%
Q2 2011+0.5%
Q3 2011-12.4%
Q3 2010-12.4%
Q4 2010-12.4%
Q1 2011-5.6%
Q2 2010-8.1%

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