NASDAQ$APLS
Apellis Pharmaceuticals Inc. · Q2 2025 earnings
Q2 2025 earnings · · Before market open · Investor relations
Briefing
Apellis Pharmaceuticals reported Q2 2025 revenue of $178.5M, a net loss of $42.2M.
For Q2 2025, Apellis Pharmaceuticals reported Revenue was $178.5M, net loss was $42.2M. Management discusses segment trends, liquidity, and outlook in the quarterly filing.
- Revenue $178.5M for Q2 2025.
- Net loss $42.2M.
- MD&A highlights operating priorities, liquidity, and sector risks.
Headline financials
Revenue & EPS history
Apellis · Revenue · Quarterly
$178M
Revenue by segment
Apellis · $110M total across 3 segments · Q3 2023
- SYFOVRE U.S. Net Product Revenue$75.3M—68.2%
- EMPAVELI U.S. Net Product Revenue$23.9M+35.2%21.6%
- Licensing and Other Revenue$11.2M+156.1%10.2%
Forward guidance
Healthcare and technology outlook emphasizes pipeline, adoption, and R&D investment.
Tailwinds
- Franchise product growth and launches.
- Cash runway for clinical and commercial programs.
Headwinds
- Reimbursement, competition, and trial risk.
- R&D spend pressuring near-term margins.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q2 2025
-0.7%
Avg return
Earnings day
+0.3%
Avg return
5 days after
+6.0%
Avg return
30 days after
43%
15 / 35 earnings
Positive
+18.6%
Q4 2022
Best reaction
-24.4%
Q2 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | -0.3% | -0.1% | — | |
| Q4 2025 | -3.8% | -6.7% | -21.5% | |
| Q3 2025 | -1.0% | -6.9% | +7.2% | |
| Q2 2025 | +17.5% | +27.4% | +45.1% | |
| Q1 2025 | -5.8% | -8.4% | +0.8% | |
| Q4 2024 | -3.3% | +0.0% | -6.7% | |
| Q3 2024 | +0.9% | +5.0% | +17.1% | |
| Q2 2024 | -7.7% | -11.3% | -1.8% | |
| Q1 2024 | -13.3% | -14.0% | -15.9% | |
| Q4 2023 | -10.7% | -10.9% | -18.1% | |
| Q3 2023 | +1.4% | -6.6% | +26.6% | |
| Q2 2023 | -24.4% | -23.4% | +26.8% | |
| Q1 2023 | +9.6% | +5.2% | +3.5% | |
| Q4 2022 | +18.6% | +20.2% | +13.9% | |
| Q3 2022 | -6.6% | -10.5% | -5.8% | |
| Q2 2022 | +1.5% | +7.3% | +1.5% | |
| Q1 2022 | -0.1% | -17.6% | +2.1% | |
| Q4 2021 | +5.2% | +2.3% | +16.3% | |
| Q3 2021 | +9.3% | +27.4% | +25.9% | |
| Q2 2021 | -5.6% | -9.3% | -12.3% | |
| Q1 2021 | +6.1% | +10.5% | +23.8% | |
| Q4 2020 | +4.3% | -1.3% | -10.2% | |
| Q3 2020 | +4.9% | +12.9% | +42.4% | |
| Q2 2020 | -0.7% | -2.5% | -3.8% | |
| Q1 2020 | -6.1% | -6.6% | -7.7% | |
| Q4 2019 | +0.5% | +5.0% | -23.8% | |
| Q3 2019 | +0.1% | -2.5% | -15.6% | |
| Q2 2019 | -2.8% | -12.5% | +0.8% | |
| Q1 2019 | +1.0% | -3.2% | +12.9% | |
| Q4 2018 | -4.8% | +22.4% | +27.5% | |
| Q3 2018 | -7.3% | +2.4% | +26.9% | |
| Q2 2018 | -3.9% | -4.3% | +8.1% | |
| Q1 2018 | -8.6% | -1.8% | -16.7% | |
| Q4 2017 | -5.6% | -5.8% | +1.3% | |
| Q3 2017 | +15.3% | +28.3% | +31.4% | |
| Q2 2017 | — | — | — | |
| Q1 2017 | — | — | — | |
| Q4 2016 | — | — | — | |
| Q3 2016 | — | — | — | |
| Q2 2016 | — | — | — | |
| Q1 2016 | — | — | — | |
| Q4 2015 | — | — | — | |
| Q3 2015 | — | — | — | |
| Q2 2015 | — | — | — | |
| Q1 2015 | — | — | — | |
| Q4 2014 | — | — | — | |
| Q3 2014 | — | — | — | |
| Q2 2014 | — | — | — | |
| Q1 2014 | — | — | — |
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