NASDAQ$APLS

Apellis Pharmaceuticals Inc. · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Apellis Pharmaceuticals reported Q1 2025 revenue of $166.8M, a net loss of $92.2M, diluted EPS of $-0.74.

For Q1 2025, Apellis Pharmaceuticals reported Revenue was $166.8M, net loss was $92.2M, diluted EPS was $-0.74. Management discusses segment trends, liquidity, and outlook in the quarterly filing.

  • Revenue $166.8M for Q1 2025.
  • Net loss $92.2M.
  • Diluted EPS $-0.74.

Headline financials

Total Revenue

$167M

Previous: $172M-3.2%
EPS (adj)

-$0.74

Previous: -$0.54-37.0%
Cost of Sales

$34.4M

No prior period
R&D Expenses

$86.4M

No prior period
SG&A Expenses

$129M

No prior period
Interest Income

$2.66M

No prior period
Interest Expense

$11M

No prior period
Income Tax Expense

$341K

No prior period
Capital Expenditures

-$8K

Previous: -$293K+97.3%
Net Income

-$92.2M

Previous: -$66.4M-38.8%
Operating Income

-$83.3M

Previous: -$62.1M-34.2%

Revenue & EPS history

Apellis · Revenue · Quarterly

$167M

Q1 2025-3.2%vs Q1 2024
Beat estimate in 9 of 16 quarters(56%)
ActualEstimate

Revenue by segment

Apellis · $110M total across 3 segments · Q3 2023

  • SYFOVRE U.S. Net Product Revenue
    $75.3M
  • EMPAVELI U.S. Net Product Revenue
    $23.9M+35.2%
  • Licensing and Other Revenue
    $11.2M+156.1%

Forward guidance

Outlook emphasizes milestones, liquidity runway, and cost discipline.

Tailwinds

  • Pipeline progress and partnership economics.
  • Cash supports near-term operating plans.

Headwinds

  • Operating losses until commercial scale.
  • Financing and competition affect funding costs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-0.7%

Avg return

Earnings day

+0.3%

Avg return

5 days after

+6.0%

Avg return

30 days after

43%

15 / 35 earnings

Positive

+18.6%

Q4 2022

Best reaction

-24.4%

Q2 2023

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.3%-0.1%
Q4 2025-3.8%-6.7%-21.5%
Q3 2025-1.0%-6.9%+7.2%
Q2 2025+17.5%+27.4%+45.1%
Q1 2025-5.8%-8.4%+0.8%
Q4 2024-3.3%+0.0%-6.7%
Q3 2024+0.9%+5.0%+17.1%
Q2 2024-7.7%-11.3%-1.8%
Q1 2024-13.3%-14.0%-15.9%
Q4 2023-10.7%-10.9%-18.1%
Q3 2023+1.4%-6.6%+26.6%
Q2 2023-24.4%-23.4%+26.8%
Q1 2023+9.6%+5.2%+3.5%
Q4 2022+18.6%+20.2%+13.9%
Q3 2022-6.6%-10.5%-5.8%
Q2 2022+1.5%+7.3%+1.5%
Q1 2022-0.1%-17.6%+2.1%
Q4 2021+5.2%+2.3%+16.3%
Q3 2021+9.3%+27.4%+25.9%
Q2 2021-5.6%-9.3%-12.3%
Q1 2021+6.1%+10.5%+23.8%
Q4 2020+4.3%-1.3%-10.2%
Q3 2020+4.9%+12.9%+42.4%
Q2 2020-0.7%-2.5%-3.8%
Q1 2020-6.1%-6.6%-7.7%
Q4 2019+0.5%+5.0%-23.8%
Q3 2019+0.1%-2.5%-15.6%
Q2 2019-2.8%-12.5%+0.8%
Q1 2019+1.0%-3.2%+12.9%
Q4 2018-4.8%+22.4%+27.5%
Q3 2018-7.3%+2.4%+26.9%
Q2 2018-3.9%-4.3%+8.1%
Q1 2018-8.6%-1.8%-16.7%
Q4 2017-5.6%-5.8%+1.3%
Q3 2017+15.3%+28.3%+31.4%
Q2 2017
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016
Q4 2015
Q3 2015
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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