NASDAQ$ANIP

ANI Pharmaceuticals Inc · Q4 2025 earnings

Q4 2025 earnings · · Before market open · Investor relations

Briefing

ANI Pharmaceuticals reported record fourth quarter 2025 net revenues and earnings, driven by strong Rare Disease and Generics growth.

ANI delivered record Q4 2025 revenue of 247060000, up 29.6% year-over-year, with strong Cortrophin Gel and Generics growth driving profitability. Net income available to common shareholders was 27490000 and adjusted non-GAAP EBITDA rose 30.6% to 65356000.

  • Total net revenues increased 29.6% year-over-year to 247060000.
  • Cortrophin Gel revenue grew 87.6% to 111431000.
  • Generics revenue increased 28.2% to 100760000.
  • Adjusted non-GAAP EBITDA rose 30.6% to 65356000.

Headline financials

Total Revenue

$247M

Previous: $191M+29.6%
EPS (adj)

$2.33

Previous: $1.63+42.9%
Total Revenue Growth

29.6%

No prior period
Cortrophin Gel Growth

87.6%

No prior period
Generics Revenue Growth

28.2%

No prior period
Adjusted EBITDA Growth

30.6%

No prior period
Net Income

$27.5M

Previous: -$10.3M+367.5%
Operating Income

$34.8M

Previous: -$4.38M+894.1%
Gross Profit

$147M

Previous: $87.7M+67.4%

Revenue & EPS history

ANI Pharmaceuticals · Revenue · Quarterly

$247M

Q4 2025+29.6%vs Q4 2024
Beat estimate in 14 of 15 quarters(93%)
ActualEstimate

Revenue by segment

ANI Pharmaceuticals · $57.6M total across 2 segments · Q1 2022

  • Generic Products
    $49.1M+48.8%
  • Brands
    $8.5M+13.3%

Forward guidance

ANI reaffirmed full year 2026 guidance, expecting continued growth in revenue and adjusted EBITDA driven by Rare Disease expansion and Generics execution.

Tailwinds

  • 2026 total net revenue guidance of 1055000000 to 1115000000.
  • Cortrophin Gel 2026 revenue guidance of 540000000 to 575000000.
  • Adjusted non-GAAP EBITDA guidance of 275000000 to 290000000.
  • Adjusted non-GAAP diluted EPS guidance of 8.83 to 9.34.
  • Expected total company adjusted non-GAAP gross margin between 59.3% and 60.3%.

Headwinds

  • Brands revenue declined 37.9% year-over-year in Q4.
  • Selling, general and administrative expenses increased 18.7% year-over-year.
  • Non-GAAP gross margin declined year-over-year due to product mix.
  • Litigation expenses impacted adjusted results.
  • Interest expense of 4411000 in the quarter.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-1.2%

Avg return

Earnings day

-3.0%

Avg return

5 days after

-2.7%

Avg return

30 days after

38%

24 / 64 earnings

Positive

+52.1%

Q3 2021

Best reaction

-24.6%

Q4 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-2.4%-3.7%
Q4 2025-3.9%-0.8%-5.6%
Q3 2025+0.4%-3.3%-9.4%
Q1 2025-7.5%-15.6%-13.4%
Q4 2024+13.4%+6.3%+10.7%
Q3 2024+5.8%+2.5%-2.4%
Q2 2024-3.6%-2.1%+2.7%
Q1 2024+2.2%-1.6%+1.3%
Q4 2023+11.4%-0.2%+3.0%
Q3 2023-17.9%-18.8%-23.1%
Q2 2023+8.4%+9.2%+10.7%
Q1 2023+13.5%+6.5%+26.2%
Q4 2022-5.3%-6.0%-11.5%
Q3 2022-5.1%-4.7%+3.2%
Q2 2022-1.8%+8.2%+7.3%
Q1 2022-5.9%+1.3%+6.9%
Q4 2021-24.6%-23.6%-9.8%
Q3 2021+52.1%+33.8%+8.2%
Q2 2021-7.9%-8.5%-11.5%
Q1 2021-6.0%-4.1%-1.8%
Q4 2020+4.1%+6.6%+5.3%
Q3 2020-15.9%-3.5%+4.1%
Q2 2020-2.0%+0.7%-6.0%
Q1 2020-7.0%-12.1%-13.0%
Q4 2019-19.1%-8.1%-41.2%
Q3 2019-22.2%-27.3%-24.7%
Q2 2019-10.8%-13.7%-21.0%
Q1 2019+3.1%-1.7%-0.3%
Q4 2018+7.7%+0.1%+8.6%
Q3 2018+7.2%+2.1%-0.2%
Q2 2018-13.0%-13.1%-13.7%
Q1 2018+3.9%+3.9%+9.6%
Q4 2017+11.3%-3.8%+0.6%
Q3 2017+7.7%+4.2%+22.8%
Q2 2017-2.9%-3.8%+6.3%
Q1 2017-2.0%+0.7%-10.3%
Q4 2016-16.3%-18.0%-17.2%
Q3 2016-18.8%-18.0%-2.1%
Q2 2016+10.0%+12.6%-3.6%
Q1 2016+6.4%
Q4 2015+9.1%
Q3 2015-4.4%
Q2 2015-14.0%
Q1 2015-15.4%
Q4 2014+4.0%
Q3 2014+27.1%
Q2 2014+9.7%
Q1 2014-3.3%
Q2 2013-3.0%
Q4 2013+24.9%
Q3 2013+4.2%
Q4 2012+0.0%
Q3 2012-0.8%
Q2 2012-15.5%
Q1 2012-15.4%
Q2 2011+0.0%
Q4 2011+0.0%
Q4 2009+0.0%
Q3 2011-6.0%
Q4 2010-7.2%
Q2 2010-7.2%
Q1 2011+0.9%
Q3 2010-6.3%
Q1 2010-5.6%

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