NASDAQ$AMGN

Amgen Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Amgen's financial performance saw revenue increase, driven by other revenue from the Lilly collaboration, while product sales experienced a slight decrease. GAAP EPS increased, influenced by revenue growth and fewer shares outstanding. The company's pipeline advancements and strategic collaborations are expected to support long-term growth.

Amgen reported a 3% increase in total revenues for Q4 2021, reaching $6.8 billion, driven by increased Other Revenue from the Eli Lilly and Company (Lilly) COVID-19 manufacturing collaboration. GAAP earnings per share (EPS) increased 22% to $3.36 in the fourth quarter driven by increased revenues and lower weighted average shares outstanding.

  • Total revenues increased by 3% to $6.8 billion, driven by increased Other Revenue from the Lilly collaboration.
  • GAAP EPS increased by 22% to $3.36, influenced by revenue growth and fewer shares outstanding.
  • Non-GAAP EPS increased by 26% to $4.36, driven by increased revenues, decreased other expense and the impact of fewer weighted average shares outstanding.
  • Prolia sales increased 17% year-over-year.

Headline financials

Total Revenue

$6.85B

Previous: $6.63B+3.2%
EPS (adj)

$4.36

Previous: $3.81+14.4%
Capital Expenditures

$287M

Previous: $173M+65.9%
Free Cash Flow

$2.52B

Previous: $1.98B+27.3%
Net Income

$1.9B

Previous: $1.62B+17.6%
Operating Income

$2.3B

Previous: $2.01B+14.7%
Gross Profit

$5.13B

Previous: $5.04B+1.8%
Cash & Equivalents

$7.99B

Previous: $6.27B+27.5%
Total Assets

$61.2B

Previous: $62.9B-2.8%
Stock-Based Comp

$341M

Previous: $330M+3.3%

Revenue & EPS history

Amgen · Revenue · Quarterly

$6.85B

Q4 2021+3.2%vs Q4 2020
Beat estimate in 12 of 16 quarters(75%)
ActualEstimate

Revenue by segment

Amgen · $5.87B total across 17 segments · Q4 2021

  • Enbrel
    $1.11B-12.9%
  • Prolia
    $873M+16.6%
  • Otezla
    $630M+2.1%
  • XGEVA
    $545M+8.6%
  • Aranesp
    $362M-3.5%
  • Neulasta
    $351M-34.5%
  • MVASI
    $304M+8.6%
  • KYPROLIS
    $284M+4.4%
  • Nplate
    $282M+24.2%
  • Repatha
    $273M+7.9%
  • Vectibix
    $243M+10.0%
  • EVENITY
    $143M+58.9%
  • BLINCYTO
    $132M+28.2%
  • AMJEVITA/AMGEVITA
    $115M+11.7%
  • Other products
    $106M+39.5%
  • Parsabiv
    $69M-59.9%
  • LUMAKRAS/LUMYKRAS
    $45M

Forward guidance

Amgen provided financial guidance for 2022 and longer-term financial guidance through the end of the decade.

Tailwinds

  • Plans to grow the many innovative medicines and biosimilars in the Company’s currently marketed portfolio
  • Advance numerous potential new medicines through its pipeline
  • Capitalize on advances in science and technology to build a set of differentiated discovery research capabilities.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+0.3%

Avg return

Earnings day

+0.0%

Avg return

5 days after

+0.1%

Avg return

30 days after

53%

39 / 73 earnings

Positive

+12.2%

Q1 2024

Best reaction

-8.7%

Q3 2016

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.9%-4.4%-2.7%
Q4 2025+3.0%+11.0%+9.1%
Q3 2025+7.7%+9.1%+11.2%
Q2 2025-5.1%-5.0%-5.5%
Q1 2025-1.1%-2.8%+1.6%
Q4 2024+6.5%+2.0%+12.4%
Q3 2024+1.3%+0.3%-10.5%
Q2 2024-3.9%-0.8%-0.3%
Q1 2024+12.2%+8.3%+10.3%
Q4 2023-8.1%-9.6%-15.3%
Q3 2023-0.9%+2.5%+2.5%
Q2 2023+5.6%+13.2%+11.4%
Q1 2023+0.4%-1.2%-9.2%
Q4 2022-2.1%-2.6%-6.7%
Q3 2022+0.0%+8.7%+6.1%
Q2 2022-0.4%+0.5%-1.9%
Q1 2022-4.7%-7.6%+2.2%
Q4 2021+8.5%+2.7%+4.2%
Q3 2021+4.0%+1.9%-4.1%
Q2 2021-4.8%-4.0%-5.8%
Q1 2021-7.4%-6.2%-7.9%
Q4 2020-1.4%-1.7%-7.7%
Q3 2020-2.5%-1.5%+0.6%
Q2 2020-1.9%-3.5%-0.3%
Q1 2020-2.0%+0.3%-2.5%
Q4 2019-4.9%-2.4%-12.1%
Q3 2019+2.9%+6.3%+14.4%
Q2 2019+6.0%+6.3%+17.5%
Q1 2019-2.8%-2.1%-6.7%
Q4 2018-3.7%-2.5%-1.0%
Q3 2018+2.4%-0.6%+7.5%
Q2 2018-0.3%+1.8%+1.9%
Q1 2018+0.1%+1.6%+1.9%
Q4 2017+0.5%-5.1%-0.5%
Q3 2017-2.1%-3.2%-5.7%
Q2 2017-2.9%-3.6%-6.1%
Q1 2017-1.2%-1.3%-5.9%
Q4 2016+4.9%+4.5%+12.9%
Q3 2016-8.7%-11.5%-8.5%
Q2 2016+2.2%+3.9%+2.6%
Q1 2016-1.7%
Q4 2015+1.5%
Q3 2015-0.9%
Q2 2015+3.0%
Q1 2015+1.9%
Q4 2014-3.2%
Q3 2014+6.7%
Q2 2014+6.0%
Q1 2014-3.2%
Q4 2013+0.5%
Q3 2013+1.8%
Q2 2013-1.0%
Q1 2013-7.5%
Q4 2012-0.8%
Q3 2012+0.8%
Q2 2012+7.6%
Q1 2012+0.2%
Q4 2011-0.8%
Q3 2011+4.9%
Q2 2011-3.0%
Q1 2011-1.5%
Q4 2007+0.7%
Q4 2010+0.7%
Q3 2008+0.7%
Q3 2010-0.9%
Q2 2010-0.4%
Q1 2009+1.5%
Q1 2010+1.2%
Q4 2009+0.5%
Q3 2009+1.6%
Q4 2008+3.8%
Q2 2009+3.8%
Q2 2008+3.8%

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