NASDAQ$ALXO
ALX Oncology Holdings Inc · Q4 2020 earnings
Q4 2020 earnings · · Investor relations
Briefing
ALX Oncology reported financial results for Q4 and full year 2020 and provided clinical development and operational highlights.
ALX Oncology reported a net loss of $18.8 million for the fourth quarter ended December 31, 2020. The company's cash and cash equivalents were $434.2 million as of December 31, 2020, which is expected to fund operations through 2024.
- ALX Oncology made substantial progress in 2020 advancing ALX148.
- Full results of a Phase 1b clinical trial with ALX148 in combination with Herceptin, Cyramza and paclitaxel in patients with ≥2L G/GEJ cancer is planned to be presented in mid-2021.
- Initiation of two randomized Phase 2 studies with ALX148 in combination with KEYTRUDA in patients with HNSCC are planned in the first half of 2021.
- Cash and cash equivalents as of December 31, 2020 were $434.2 million.
Headline financials
Revenue & EPS history
ALX Oncology · Revenue · Quarterly
$1.18
Forward guidance
ALX Oncology anticipates several key clinical milestones for 2021, including presenting full results from Phase 1b clinical trials and initiating multiple Phase 2 and Phase 1b clinical trials.
Tailwinds
- Full results of a Phase 1b clinical trial with ALX148 in combination with Herceptin, Cyramza and paclitaxel in patients with second line or greater G/GEJ cancer (ASPEN-01) is planned to be presented in mid-2021.
- Initiation of two randomized Phase 2 studies with ALX148 in combination with KEYTRUDA in patients with HNSCC are planned in the first half of 2021.
- Initiation of a Phase 1b clinical trial with ALX148 in combination with Zymeworks’ zanidatamab in patients with advanced HER2-expressing breast cancer and other solid tumors in the first half of 2021.
- Full results of a Phase 1b study of ALX148 in combination with Merck’s KEYTRUDA and chemotherapy for the treatment of patients with HNSCC (ASPEN-01) is planned to be presented in the second half of 2021.
- Results of a Phase 1 clinical trial of ALX148 in combination with azacitidine in patients with MDS and the initiation of the Phase 2 clinical trial in MDS (ASPEN-02) are expected in the fourth quarter 2021.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q4 2020
+1.0%
Avg return
Earnings day
+2.2%
Avg return
5 days after
+2.7%
Avg return
30 days after
59%
13 / 22 earnings
Positive
+26.0%
Q4 2024
Best reaction
-21.9%
Q4 2020
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2026 | -10.2% | -6.8% | -13.2% | |
| Q3 2025 | +15.5% | +8.5% | +20.3% | |
| Q2 2025 | +7.4% | +57.9% | +72.4% | |
| Q1 2025 | -8.2% | -0.2% | +25.9% | |
| Q4 2024 | +26.0% | -6.4% | -50.4% | |
| Q3 2024 | -5.2% | -12.4% | +5.9% | |
| Q1 2024 | -2.4% | -8.7% | -45.8% | |
| Q4 2023 | +3.0% | -16.2% | -17.2% | |
| Q3 2023 | +13.2% | +21.8% | +70.5% | |
| Q2 2023 | +1.4% | -2.6% | -1.4% | |
| Q1 2023 | +0.6% | -7.0% | +23.3% | |
| Q4 2022 | -13.6% | -15.9% | -28.7% | |
| Q3 2022 | -1.8% | +1.1% | -14.2% | |
| Q2 2022 | +2.6% | +26.6% | +5.6% | |
| Q1 2022 | -6.8% | -8.1% | -24.1% | |
| Q4 2021 | +7.7% | -1.3% | +2.7% | |
| Q3 2021 | +8.8% | +6.3% | -26.4% | |
| Q2 2021 | +0.6% | +2.1% | +16.6% | |
| Q1 2021 | -1.1% | -1.6% | +7.3% | |
| Q4 2020 | -21.9% | -19.4% | -24.8% | |
| Q3 2020 | +4.2% | +34.6% | +65.1% | |
| Q2 2020 | +2.0% | -3.8% | -10.0% | |
| Q4 2019 | — | — | — | |
| Q3 2019 | — | — | — | |
| Q2 2019 | — | — | — | |
| Q1 2019 | — | — | — |
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