NASDAQ$ALXO
ALX Oncology Holdings Inc · Q3 2024 earnings
Q3 2024 earnings · · Investor relations
Briefing
ALX Oncology reported financial results for the third quarter ended September 30, 2024, and provided a corporate update.
ALX Oncology announced topline data from its ASPEN-06 Phase 2 trial, showcasing evorpacept as the first CD47-blocking agent with durable clinical benefit and a well-tolerated safety profile in a randomized clinical trial. The company reported cash, cash equivalents, and investments of $162.6 million as of September 30, 2024, sufficient to fund planned operations well into Q1 2026.
- Reported topline data from the ASPEN-06 Phase 2 clinical trial, demonstrating evorpacept's durable clinical benefit and safety profile in HER2-positive gastric/GEJ cancer patients.
- Commenced patient dosing in the Sanofi-partnered arm of the UMBRELLA phase 1/2 clinical study, investigating evorpacept plus SARCLISA and dexamethasone in relapsed or refractory multiple myeloma patients.
- Appointed Alan Sandler, M.D. to Board of Directors, bringing over 30 years of oncology and drug development experience.
- Cash, cash equivalents and investments as of September 30, 2024, were $162.6 million.
Headline financials
Revenue & EPS history
ALX Oncology · Revenue · Quarterly
$0
Forward guidance
Upcoming clinical milestones for Evorpacept's development pipeline include data presentations and trial initiations across various cancer indications.
Tailwinds
- Breast Cancer – Results from a Phase 1b/2 combination trial evaluating evorpacept in combination with Jazz Pharmaceuticals’ zanidatamab in HER2-positive and HER2-low metastatic breast cancer will be presented at a poster spotlight presentation at the San Antonio Breast Cancer Symposium on December 12, 2024
- Gastric/GEJ Cancer – Updated results of ASPEN-06 Phase 2 clinical trial (1H 2025)
- Head and Neck Squamous Cell Carcinoma – Topline results from a Phase 2 randomized clinical trial of ASPEN-03 with KEYTRUDA® (pembrolizumab) (1H 2025)
- Urothelial Cancer – Updated results from a Phase 1 clinical trial of ASPEN-07 in combination with PADCEV® (enfortumab vedotin) (1H 2025)
- Gastric/GEJ Cancer – Initiation of Phase 3 registrational randomized clinical trial for evorpacept (mid-2025)
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q3 2024
+1.0%
Avg return
Earnings day
+2.2%
Avg return
5 days after
+2.7%
Avg return
30 days after
59%
13 / 22 earnings
Positive
+26.0%
Q4 2024
Best reaction
-21.9%
Q4 2020
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2026 | -10.2% | -6.8% | -13.2% | |
| Q3 2025 | +15.5% | +8.5% | +20.3% | |
| Q2 2025 | +7.4% | +57.9% | +72.4% | |
| Q1 2025 | -8.2% | -0.2% | +25.9% | |
| Q4 2024 | +26.0% | -6.4% | -50.4% | |
| Q3 2024 | -5.2% | -12.4% | +5.9% | |
| Q1 2024 | -2.4% | -8.7% | -45.8% | |
| Q4 2023 | +3.0% | -16.2% | -17.2% | |
| Q3 2023 | +13.2% | +21.8% | +70.5% | |
| Q2 2023 | +1.4% | -2.6% | -1.4% | |
| Q1 2023 | +0.6% | -7.0% | +23.3% | |
| Q4 2022 | -13.6% | -15.9% | -28.7% | |
| Q3 2022 | -1.8% | +1.1% | -14.2% | |
| Q2 2022 | +2.6% | +26.6% | +5.6% | |
| Q1 2022 | -6.8% | -8.1% | -24.1% | |
| Q4 2021 | +7.7% | -1.3% | +2.7% | |
| Q3 2021 | +8.8% | +6.3% | -26.4% | |
| Q2 2021 | +0.6% | +2.1% | +16.6% | |
| Q1 2021 | -1.1% | -1.6% | +7.3% | |
| Q4 2020 | -21.9% | -19.4% | -24.8% | |
| Q3 2020 | +4.2% | +34.6% | +65.1% | |
| Q2 2020 | +2.0% | -3.8% | -10.0% | |
| Q4 2019 | — | — | — | |
| Q3 2019 | — | — | — | |
| Q2 2019 | — | — | — | |
| Q1 2019 | — | — | — |
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