LSE$AZN
AstraZeneca · Q3 2025 earnings
Q3 2025 earnings · · Investor relations
Briefing
AstraZeneca reported strong Q3 2025 results with double-digit growth in revenue and EPS, driven by solid performance across oncology and biopharmaceuticals.
AstraZeneca delivered robust financials in Q3 2025, posting $15.19 billion in revenue and a 64% increase in operating profit. The company continued to benefit from strong demand in oncology, respiratory, and cardiovascular portfolios.
- Total revenue reached $15.19 billion, up 10% at constant exchange rates.
- Reported EPS rose to $1.64, with Core EPS at $2.38.
- Operating income surged 64% to $3.58 billion.
- Gross margin improved by 4 percentage points to 82%.
Headline financials
Revenue & EPS history
AstraZeneca · Revenue · Quarterly
$15.2B
Forward guidance
Guidance for FY 2025 was reiterated with high single-digit revenue growth and low double-digit Core EPS growth expected.
Tailwinds
- High single-digit growth expected in Total Revenue.
- Low double-digit growth expected in Core EPS.
- Core tax rate expected between 18% and 22%.
- FX impact expected to be neutral for revenue and EPS.
- Strong cash flow generation supported investment and debt reduction.
Headwinds
- Biosimilar competition impacting Soliris revenue.
- Brilinta continues to decline due to generic erosion.
- Unfavorable tender order timing in some Emerging Markets.
- Operating expenses remain high due to R&D and SG&A investments.
- Global macroeconomic uncertainties remain a risk to forecasts.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 20 quarterly earnings reports · overlaid with Q3 2025
+0.8%
Avg return
Earnings day
+1.8%
Avg return
5 days after
+181.0%
Avg return
30 days after
56%
23 / 41 earnings
Positive
+11.9%
Q4 2018
Best reaction
-10.8%
Q2 2017
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q4 2026 | +0.4% | +0.1% | +6432.5% | |
| Q3 2025 | +2.9% | +9.8% | +11.1% | |
| Q2 2025 | +6.8% | +3.0% | +11.4% | |
| Q4 2024 | +1.5% | +3.4% | +4.2% | |
| Q1 2024 | +5.6% | -2.3% | +8.7% | |
| Q4 2023 | -6.4% | -8.3% | -0.1% | |
| Q3 2023 | -0.6% | +1.1% | -0.4% | |
| Q2 2023 | +5.2% | +3.4% | +0.2% | |
| Q1 2023 | -0.6% | +0.1% | -1.5% | |
| Q4 2022 | +7.0% | +9.3% | -0.3% | |
| Q3 2022 | +2.8% | +4.8% | +13.9% | |
| Q2 2022 | -1.6% | -2.1% | -0.6% | |
| Q1 2022 | -1.2% | -0.7% | +0.3% | |
| Q4 2021 | +1.5% | +5.4% | +5.4% | |
| Q3 2021 | -5.0% | -8.2% | -14.1% | |
| Q2 2021 | +0.8% | +2.6% | -4.1% | |
| Q1 2021 | +4.5% | +4.4% | +10.5% | |
| Q4 2020 | +3.4% | +1.8% | -3.1% | |
| Q3 2020 | +0.9% | +2.8% | -2.4% | |
| Q2 2020 | -1.5% | -1.0% | -1.7% | |
| Q1 2020 | +2.6% | +2.7% | +7.1% | |
| Q4 2019 | -0.4% | -0.0% | -14.3% | |
| Q3 2019 | +6.7% | +6.5% | +7.3% | |
| Q2 2019 | +7.8% | +1.4% | +14.0% | |
| Q1 2019 | -2.3% | +8.7% | +10.5% | |
| Q4 2018 | +11.9% | +10.6% | +16.2% | |
| Q3 2018 | +4.5% | +5.8% | -2.6% | |
| Q2 2018 | +2.1% | +4.5% | +2.3% | |
| Q1 2018 | +1.0% | +1.1% | -0.1% | |
| Q4 2017 | -3.9% | +0.7% | +4.9% | |
| Q3 2017 | -1.3% | -0.2% | -1.8% | |
| Q2 2017 | -10.8% | -11.8% | -13.8% | |
| Q1 2017 | -1.1% | +0.4% | +10.7% | |
| Q4 2016 | +0.6% | +1.8% | +7.8% | |
| Q3 2016 | -3.4% | -4.6% | -6.2% | |
| Q2 2016 | +8.2% | +8.5% | +4.8% | |
| Q1 2016 | +0.0% | — | — | |
| Q4 2015 | -7.3% | — | — | |
| Q3 2015 | -0.1% | — | — | |
| Q1 2015 | -3.3% | — | — | |
| Q4 2014 | -4.7% | — | — | |
| Q3 2014 | — | — | — | |
| Q2 2014 | — | — | — | |
| Q1 2014 | — | — | — | |
| Q4 2013 | — | — | — |
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