LSE$AZN

AstraZeneca · Q2 2025 earnings

Q2 2025 earnings · · Investor relations

Briefing

AstraZeneca reported strong Q2 2025 performance with robust revenue growth and solid profitability across its core business areas.

AstraZeneca delivered a strong Q2 2025 with $14.46 billion in revenue and $3.5 billion in net income. The company saw continued growth in its oncology, biopharmaceuticals, and rare disease portfolios, supported by new molecular entities entering Phase III trials.

  • Q2 2025 revenue reached $14.46 billion, up 11% at constant exchange rates
  • Reported EPS was $1.09 per ADS; Core EPS was $2.17 per share
  • Net income for the quarter was $3.5 billion with operating income at $4.584 billion
  • Five new molecular entities advanced to Phase III trials, supporting future pipeline momentum

Headline financials

Total Revenue

$14.5B

No prior period
EPS (adj)

$1.09

No prior period
Gross margin

82.0%

No prior period
Core tax rate

21.0%

No prior period
Core op profit growth

14.0%

No prior period
Net Income

$3.51B

No prior period
Operating Income

$4.58B

No prior period

Revenue & EPS history

AstraZeneca · Revenue · Quarterly

$14.5B

Q2 2025
Beat estimate in 10 of 15 quarters(67%)
ActualEstimate

Forward guidance

AstraZeneca reiterated its FY 2025 guidance, expecting high single-digit revenue growth and low double-digit Core EPS growth.

Tailwinds

  • Strong performance across oncology and rare disease portfolios
  • Solid pipeline momentum with multiple Phase III readouts
  • Operational leverage through SG&A efficiency
  • 27% increase in net cash inflow from operations in H1 2025
  • Expected neutral impact from FX on Total Revenue and Core EPS

Headwinds

  • Continued pressure from biosimilars on legacy rare disease products
  • Brilinta sales impacted by generics
  • Some regional revenue fluctuations due to tender market dynamics
  • Elevated R&D and SG&A expenses relative to H1 2024
  • Tax rate increased slightly compared to previous periods

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q2 2025

Historical avgQ2 2025

+0.8%

Avg return

Earnings day

+1.8%

Avg return

5 days after

+181.0%

Avg return

30 days after

56%

23 / 41 earnings

Positive

+11.9%

Q4 2018

Best reaction

-10.8%

Q2 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+0.4%+0.1%+6432.5%
Q3 2025+2.9%+9.8%+11.1%
Q2 2025+6.8%+3.0%+11.4%
Q4 2024+1.5%+3.4%+4.2%
Q1 2024+5.6%-2.3%+8.7%
Q4 2023-6.4%-8.3%-0.1%
Q3 2023-0.6%+1.1%-0.4%
Q2 2023+5.2%+3.4%+0.2%
Q1 2023-0.6%+0.1%-1.5%
Q4 2022+7.0%+9.3%-0.3%
Q3 2022+2.8%+4.8%+13.9%
Q2 2022-1.6%-2.1%-0.6%
Q1 2022-1.2%-0.7%+0.3%
Q4 2021+1.5%+5.4%+5.4%
Q3 2021-5.0%-8.2%-14.1%
Q2 2021+0.8%+2.6%-4.1%
Q1 2021+4.5%+4.4%+10.5%
Q4 2020+3.4%+1.8%-3.1%
Q3 2020+0.9%+2.8%-2.4%
Q2 2020-1.5%-1.0%-1.7%
Q1 2020+2.6%+2.7%+7.1%
Q4 2019-0.4%-0.0%-14.3%
Q3 2019+6.7%+6.5%+7.3%
Q2 2019+7.8%+1.4%+14.0%
Q1 2019-2.3%+8.7%+10.5%
Q4 2018+11.9%+10.6%+16.2%
Q3 2018+4.5%+5.8%-2.6%
Q2 2018+2.1%+4.5%+2.3%
Q1 2018+1.0%+1.1%-0.1%
Q4 2017-3.9%+0.7%+4.9%
Q3 2017-1.3%-0.2%-1.8%
Q2 2017-10.8%-11.8%-13.8%
Q1 2017-1.1%+0.4%+10.7%
Q4 2016+0.6%+1.8%+7.8%
Q3 2016-3.4%-4.6%-6.2%
Q2 2016+8.2%+8.5%+4.8%
Q1 2016+0.0%
Q4 2015-7.3%
Q3 2015-0.1%
Q1 2015-3.3%
Q4 2014-4.7%
Q3 2014
Q2 2014
Q1 2014
Q4 2013

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