NYSE$LCTX
Lineage Cell Therapeutics In · Q4 2025 earnings
Q4 2025 earnings · · After market close · Investor relations
Briefing
Lineage reported higher fourth quarter revenue and achieved net income driven by collaboration milestone revenue.
Lineage generated approximately $6600000 in revenue during the fourth quarter of 2025, primarily from collaboration activities following a milestone under its Roche agreement and a new research collaboration. The company reported net income of about $900000 despite increased operating expenses driven by higher research and development spending.
- Fourth quarter revenue increased to approximately $6600000 from $2900000 year over year.
- Net income was approximately $900000 compared with a net loss of $3300000 in the prior year period.
- Research and development expenses increased significantly to $8200000 due to program expansion.
- Operating loss was approximately $6500000 as operating expenses rose to $13200000.
Headline financials
Revenue & EPS history
Lineage · Revenue · Quarterly
$6.6M
Revenue by segment
Lineage · $700K total across 1 segment · Q4 2019
- Royalties and licensing$700K—100.0%
Forward guidance
Lineage expects its existing cash and equivalents to support planned operations into the second quarter of 2028 while continuing development of its cell therapy pipeline and advancing collaboration programs.
Tailwinds
- Cash and equivalents expected to fund operations into Q2 2028.
- Milestone achievement under Roche and Genentech collaboration supports revenue growth.
- Advancement of OpRegen cell therapy program and ongoing Phase 2a GAlette study.
- New research collaboration with William Demant Invest to support ReSonance program.
- Manufacturing progress with AlloSCOPE platform supporting scalable cell therapy production.
Headwinds
- Operating expenses increased significantly year over year.
- R&D spending is rising as programs advance.
- Clinical development risk remains for early-stage pipeline programs.
- Dependence on collaboration revenue and milestones for near-term revenue growth.
- Manufacturing and clinical trial progress may be impacted by operational or geopolitical factors.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q4 2025
+0.2%
Avg return
Earnings day
-1.1%
Avg return
5 days after
-0.6%
Avg return
30 days after
50%
31 / 62 earnings
Positive
+16.6%
Q4 2016
Best reaction
-14.5%
Q1 2010
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +1.5% | -4.6% | — | |
| Q4 2025 | +0.5% | -8.7% | -14.7% | |
| Q3 2025 | +1.2% | +11.6% | -0.6% | |
| Q1 2025 | -0.1% | +6.4% | +72.3% | |
| Q4 2024 | +0.4% | -1.9% | -22.6% | |
| Q3 2024 | -5.3% | -1.1% | -44.0% | |
| Q2 2024 | +4.4% | -4.6% | -3.4% | |
| Q1 2024 | +0.9% | -10.3% | -16.4% | |
| Q4 2023 | +15.0% | +9.7% | +23.9% | |
| Q3 2023 | -5.5% | -8.2% | -5.5% | |
| Q2 2023 | +0.0% | +1.4% | -5.6% | |
| Q1 2023 | -3.5% | -4.9% | -3.5% | |
| Q4 2022 | -2.1% | -4.8% | -6.2% | |
| Q3 2022 | +15.2% | +4.8% | -2.4% | |
| Q2 2022 | +0.6% | -3.2% | -16.7% | |
| Q1 2022 | -5.9% | +1.7% | +17.6% | |
| Q4 2021 | -5.6% | -14.8% | -3.5% | |
| Q3 2021 | -0.4% | +0.4% | -19.0% | |
| Q2 2021 | -1.1% | -7.9% | -12.1% | |
| Q1 2021 | -0.4% | +0.9% | +26.4% | |
| Q4 2020 | +10.2% | +21.0% | +32.3% | |
| Q3 2020 | +7.4% | +7.4% | +32.0% | |
| Q2 2020 | +3.7% | +2.3% | -2.3% | |
| Q1 2020 | -3.7% | -11.5% | -7.3% | |
| Q4 2019 | -5.3% | -12.7% | -2.5% | |
| Q3 2019 | +6.6% | +19.2% | -5.5% | |
| Q2 2019 | -8.9% | -8.9% | -8.9% | |
| Q1 2019 | +0.8% | -10.8% | -16.7% | |
| Q4 2018 | +10.2% | +0.0% | -17.8% | |
| Q3 2018 | -8.6% | -17.1% | -27.1% | |
| Q2 2018 | -3.7% | -4.6% | +14.1% | |
| Q1 2018 | +0.9% | +2.3% | +3.7% | |
| Q4 2017 | +0.7% | -4.3% | -10.1% | |
| Q3 2017 | +14.3% | +6.3% | +8.5% | |
| Q2 2017 | +6.4% | +6.0% | +8.3% | |
| Q1 2017 | +0.3% | +1.9% | +1.6% | |
| Q4 2016 | +16.6% | +5.5% | +5.8% | |
| Q3 2016 | +0.3% | +0.3% | +1.3% | |
| Q2 2016 | -5.4% | -6.0% | +5.1% | |
| Q1 2016 | -4.6% | — | — | |
| Q4 2015 | +9.5% | — | — | |
| Q3 2015 | -7.6% | — | — | |
| Q2 2015 | -6.2% | — | — | |
| Q4 2014 | +1.2% | — | — | |
| Q3 2014 | +0.3% | — | — | |
| Q1 2014 | +6.4% | — | — | |
| Q4 2013 | -7.0% | — | — | |
| Q3 2013 | -1.8% | — | — | |
| Q2 2013 | +0.5% | — | — | |
| Q1 2013 | +8.5% | — | — | |
| Q4 2012 | -9.5% | — | — | |
| Q3 2012 | -4.5% | — | — | |
| Q2 2012 | -4.3% | — | — | |
| Q1 2012 | -2.1% | — | — | |
| Q4 2011 | -4.2% | — | — | |
| Q3 2011 | -7.1% | — | — | |
| Q2 2011 | +3.0% | — | — | |
| Q1 2011 | -2.9% | — | — | |
| Q4 2010 | -4.7% | — | — | |
| Q3 2010 | +6.9% | — | — | |
| Q2 2010 | +2.1% | — | — | |
| Q1 2010 | -14.5% | — | — |
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