NASDAQ$VYGR

Voyager Therapeutics Inc · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Voyager Therapeutics reported a decrease in collaboration revenue and an increase in net loss for the first quarter of 2025.

Voyager Therapeutics reported a net loss of $31.0 million for the first quarter of 2025, compared to a net loss of $11.3 million in the same period last year. Collaboration revenue decreased to $6.5 million from $19.5 million in Q1 2024, primarily due to reduced revenue from Neurocrine collaboration agreements. The company ended the quarter with a strong cash position of $295 million, providing runway into mid-2027.

  • Net loss for Q1 2025 was $31.0 million, a significant increase from $11.3 million in Q1 2024.
  • Collaboration revenue decreased to $6.5 million in Q1 2025 from $19.5 million in Q1 2024.
  • Cash, cash equivalents, and marketable securities stood at $295 million as of March 31, 2025, providing runway into mid-2027.
  • Research and development expenses increased to $31.5 million in Q1 2025, up from $27.1 million in Q1 2024, driven by increased program-related spending.

Headline financials

Total Revenue

$6.47M

Previous: $19.5M-66.8%
EPS (adj)

-$0.53

Previous: -$0.20-165.0%
Collaboration Revenue Growth

-66.8%

No prior period
R&D Expenses

$31.5M

No prior period
G&A Expenses

$9.64M

No prior period
Net Loss Change

173.8%

No prior period
Capital Expenditures

-$658K

Previous: -$2.14M+69.3%
Net Income

-$31M

Previous: -$11.3M-173.8%
Operating Income

-$34.7M

Previous: -$16.2M-114.4%
Gross Profit

$5.46M

Previous: $18.3M-70.2%
R&D Expense

$30.5M

Previous: $25.9M+17.8%

Revenue & EPS history

Voyager Therapeutics · Revenue · Quarterly

$6.47M

Q1 2025-66.8%vs Q1 2024
Beat estimate in 9 of 15 quarters(60%)
ActualEstimate

Revenue by segment

Voyager Therapeutics · $4.6M total across 1 segment · Q3 2023

  • Collaboration Revenue
    $4.6M-88.8%

Forward guidance

Voyager Therapeutics anticipates its cash, cash equivalents, and marketable securities, along with expected reimbursements from Neurocrine and Novartis collaborations and interest income, to be sufficient to meet operating expenses and capital expenditure requirements into mid-2027.

Tailwinds

  • Strong cash position of $295 million expected to provide runway into mid-2027.
  • Potential milestone payments from existing partnerships, including up to $35 million from Neurocrine-partnered FA and GBA1 programs in 2025-2026.
  • Anticipated IND submissions in 2025 for Neurocrine-partnered FA and GBA1 programs.
  • Expected initiation of first clinical trials for FA and GBA1 programs in 2026.
  • Anticipated U.S. IND and Canadian CTA filings for VY1706 for AD in 2026.

Headwinds

  • Cash use during Q1 2025 was higher than typical due to one-time payments and start-up activities for the VY7523 MAD trial.
  • Neurocrine deprioritized two discovery-stage programs against undisclosed targets, with rights returning to Voyager.
  • Uncertainty regarding the timing, initiation, conduct, and outcomes of preclinical and clinical studies.
  • Potential for increased costs of critical research components and restricted supply.
  • Risks associated with the success of programs controlled by third-party collaboration partners.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.2%

Avg return

Earnings day

-1.6%

Avg return

5 days after

+2.3%

Avg return

30 days after

45%

19 / 42 earnings

Positive

+60.3%

Q4 2021

Best reaction

-21.7%

Q3 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-5.0%-0.5%
Q4 2025+21.7%+8.5%-3.6%
Q3 2025+0.0%-7.7%+3.5%
Q1 2025+0.0%-9.4%+0.3%
Q4 2024+2.3%-2.0%-20.2%
Q3 2024-4.6%-19.5%-10.8%
Q2 2024-11.7%-13.2%-20.5%
Q1 2024-1.5%-1.1%-1.8%
Q4 2023-6.6%+8.2%+4.5%
Q3 2023+1.6%-5.4%+13.4%
Q2 2023-1.7%-1.2%+12.2%
Q1 2023+19.0%+25.6%+53.9%
Q4 2022+2.1%-5.5%+0.4%
Q3 2022+6.5%+14.6%+25.7%
Q2 2022-2.0%-13.6%-6.4%
Q1 2022-18.4%-38.0%-23.9%
Q4 2021+60.3%+42.2%+129.8%
Q3 2021+7.5%+2.4%-21.0%
Q2 2021+10.4%-3.1%+4.7%
Q1 2021+2.1%+5.6%+9.1%
Q4 2020-14.0%-14.0%-26.9%
Q3 2020-21.7%-22.1%-28.1%
Q2 2020+0.1%+0.7%-6.8%
Q1 2020-5.9%+8.0%+4.9%
Q4 2019+6.6%-3.3%-23.3%
Q3 2019-2.6%-5.0%-5.9%
Q2 2019-2.8%+2.3%-21.1%
Q1 2019+1.9%+1.6%-4.3%
Q4 2018+11.5%+19.0%+37.0%
Q3 2018-9.6%-15.6%-21.3%
Q2 2018-15.7%-10.5%-3.6%
Q1 2018-4.3%+8.0%+17.6%
Q4 2017-9.9%-13.2%-22.7%
Q3 2017-17.5%-34.6%-29.5%
Q2 2017+6.6%+4.3%+71.7%
Q1 2017+6.1%+4.0%-0.1%
Q4 2016-1.9%-0.3%-2.5%
Q3 2016+2.9%+17.3%+21.4%
Q2 2016+3.0%+2.8%-18.3%
Q1 2016-6.5%
Q4 2015-7.2%
Q3 2015+9.2%
Q2 2015
Q1 2015
Q4 2014
Q3 2014
Q2 2014
Q1 2014

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