NASDAQ$VERV

Verve Therapeutics Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Verve Therapeutics reported financial results and pipeline updates.

Verve Therapeutics reported a net loss of $48.4 million for Q4 2023, with cash, cash equivalents, and marketable securities totaling $624.0 million as of December 31, 2023, expected to fund operations into late 2026. The company made progress with its clinical programs, including VERVE-101, VERVE-102, and VERVE-201, and anticipates having three in vivo gene editing programs in the clinic in 2024.

  • First human proof-of-concept data for in vivo base editing demonstrated in Heart-1 Phase 1b clinical trial of VERVE-101.
  • Three clinical-stage programs targeting PCSK9 and ANGPTL3 are expected in 2024.
  • IND clearance received from U.S. FDA for VERVE-101.
  • Cash, cash equivalents, and marketable securities totaled $624 million, providing a cash runway into late 2026.

Headline financials

Total Revenue

$5.14M

Previous: $1.01M+408.3%
EPS (adj)

-$0.69

Previous: -$0.67-3.0%
Capital Expenditures

-$2.19M

Previous: $4.97M-144.0%
Net Income

-$48.4M

Previous: -$41.1M-17.7%
Operating Income

-$53.9M

Previous: -$47.7M-13.1%
Gross Profit

$3.63M

No prior period
R&D Expense

$46.8M

No prior period
Stock-Based Comp

$9.25M

Previous: $6.7M+38.0%

Revenue & EPS history

Verve Therapeutics · Revenue · Quarterly

$5.14M

Q4 2023+408.3%vs Q4 2022
Beat estimate in 10 of 10 quarters(100%)
ActualEstimate

Revenue by segment

Verve Therapeutics · $3.12M total across 1 segment · Q3 2023

  • Collaboration Revenue
    $3.12M

Forward guidance

Verve Therapeutics anticipates several milestones in 2024, including dosing the first patient in the U.S. in the VERVE-101 trial, completing enrollment in the Phase 1b trial of VERVE-101, initiating the Heart-2 Phase 1b trial for VERVE-102, and initiating a Phase 1b trial for VERVE-201.

Tailwinds

  • Dose the first patient in the United States in the VERVE-101 trial.
  • Complete enrollment in the ongoing Phase 1b trial of VERVE-101 and provide a data update.
  • Initiate the Heart-2 Phase 1b trial for VERVE-102 targeting PCSK9 in the first half of the year.
  • Initiate a Phase 1b trial for VERVE-201 targeting ANGPTL3 in the second half of the year.
  • Have three in vivo gene editing programs in the clinic in 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

-1.0%

Avg return

Earnings day

+0.3%

Avg return

5 days after

-3.8%

Avg return

30 days after

47%

8 / 17 earnings

Positive

+24.4%

Q4 2023

Best reaction

-34.2%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2025+3.4%+5.0%+48.1%
Q4 2025-1.7%-2.9%-16.3%
Q3 2024+6.0%+4.5%+1.0%
Q2 2024-12.1%-20.8%-1.6%
Q1 2024+3.2%+0.8%-15.6%
Q4 2023+24.4%+12.7%-8.2%
Q3 2023+11.8%+4.8%-13.8%
Q2 2023+2.6%-9.9%-28.0%
Q1 2023-5.2%-4.5%-2.6%
Q4 2022+7.0%+3.0%-20.8%
Q3 2022-34.2%-13.7%-31.5%
Q2 2022+17.5%+31.2%+47.0%
Q1 2022-4.4%+12.8%+15.2%
Q4 2021-20.1%-4.3%-19.7%
Q3 2021-2.7%-7.8%-34.7%
Q4 2020-1.4%+5.5%+7.5%
Q2 2021-10.7%-11.9%+10.1%
Q1 2021
Q3 2020
Q2 2020
Q1 2020

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