NASDAQ$UPB

Upstream Bio Inc · Q1 2025 earnings

Q1 2025 earnings ·

Briefing

Upstream Bio reported Q1 2025, revenue of $85M, net income of $14M, diluted EPS of $0.35.

For Q1 2025, Upstream Bio reported revenue of $85M, net income of $14M, diluted EPS was $0.35. The filing highlights segment performance, liquidity, and management commentary on the period.

  • Revenue $85M.
  • Net income $14M.
  • Diluted EPS $0.35.

Headline financials

Total Revenue

$566K

No prior period
EPS (adj)

$0.35

No prior period
Free Cash Flow

-$27.3M

No prior period
Net Income

-$27.3M

No prior period
Operating Income

-$32M

No prior period
Gross Profit

-$2.13M

No prior period

Revenue & EPS history

Upstream Bio Inc · Revenue · Quarterly

$566K

Q1 2025
Beat estimate in 1 of 1 quarters(100%)
ActualEstimate

Forward guidance

Management discusses operating priorities, capital allocation, and sector risks in the quarterly filing.

Tailwinds

  • Headline results and segment trends anchor the quarter.
  • Liquidity and balance-sheet capacity support operations.
  • Strategic initiatives outlined in MD&A.

Headwinds

  • Macro, rates, or input costs may pressure margins.
  • One-time items affect year-over-year comparability.
  • Execution risk on growth or restructuring plans.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 3 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.8%

Avg return

Earnings day

-2.0%

Avg return

5 days after

+4.5%

Avg return

30 days after

67%

4 / 6 earnings

Positive

+7.9%

Q2 2025

Best reaction

-5.4%

Q1 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+0.5%-8.4%
Q1 2026+4.7%-5.3%-31.9%
Q3 2025-4.3%-6.2%+10.8%
Q2 2025+7.9%+7.0%+28.8%
Q1 2025-5.4%+1.6%+24.8%
Q3 2024+1.7%-0.7%-10.3%

Discussion

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