NASDAQ$TEM

Tempus AI Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Tempus AI reported Q4 2025, revenue of $367.2M, net loss of $54.2M.

For Q4 2025, Tempus AI reported revenue of $367.2M, a net loss of $54.2M per the quarterly earnings release and SEC filing.

  • Revenue $367.2M.
  • Net loss $54.2M.
  • Tempus AI discussed capital allocation and operating priorities.

Headline financials

Total Revenue

$367M

Previous: $201M+83.0%
EPS (adj)

-$0.04

Previous: -$0.18+77.8%
Gross Margin

64.7%

Previous: 60.8%+6.4%
Adjusted EBITDA

$12.9M

Previous: -$7.75M+266.3%
Stock-Based Compensation

$45.3M

Previous: $24.8M+82.9%
Net Income

-$54.2M

Previous: -$13M-316.5%
Operating Income

-$61.4M

Previous: -$50.7M-21.1%
Gross Profit

$238M

Previous: $122M+94.7%

Revenue & EPS history

Tempus AI Inc · Revenue · Quarterly

$367M

Q4 2025+83%vs Q4 2024
Beat estimate in 6 of 8 quarters(75%)
ActualEstimate

Revenue by segment

Tempus AI Inc · $146M total across 2 segments · Q1 2024

  • Diagnostics
    $103M
  • Data and Applications
    $43.3M

Forward guidance

FY26 revenue ~$1.59B (~25% growth); adjusted EBITDA ~$65M.

Tailwinds

  • Diagnostics revenue +83% in Q4.
  • MRD volume growth.
  • Data & applications +25%.

Headwinds

  • Stock compensation drag.
  • Integration of acquisitions.
  • Healthcare reimbursement dynamics.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 10 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-0.5%

Avg return

Earnings day

+10.9%

Avg return

5 days after

+12.9%

Avg return

30 days after

50%

5 / 10 earnings

Positive

+12.6%

Q1 2025

Best reaction

-15.0%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.1%-10.7%-7.2%
Q4 2025+3.6%-8.0%-26.5%
Q3 2025-2.7%-15.0%-9.3%
Q2 2025+3.4%+18.5%+35.5%
Q1 2025+12.6%+20.1%+18.9%
Q4 2024-15.0%-19.2%-25.3%
Q3 2024-3.4%+60.2%+25.9%
Q3 2023-3.4%+60.2%+25.9%
Q2 2024+1.6%+1.4%+45.6%
Q2 2023+1.6%+1.4%+45.6%
Q1 2024
Q1 2023
Q4 2022
Q3 2021
Q3 2020

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