NASDAQ$TCRX

Tscan Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Reported full year 2021 financial results and highlighted key 2022 priorities.

TScan Therapeutics reported its full year 2021 financial results, highlighting FDA clearance of IND for TSC-100, the upcoming initiation of a Phase 1 trial for the liquid tumor program, and a strong balance sheet with $161.4 million in cash and cash equivalents.

  • Received FDA clearance of IND for TSC-100 for hematologic malignancies treatment.
  • Phase 1 umbrella trial for liquid tumor program is expected to start in H1 2022, with preliminary data anticipated in H2 2022.
  • Two INDs for the TSC-200 series are expected by the end of the year.
  • The company reported a strong financial position, with $161.4 million in cash and cash equivalents as of December 31, 2021, which is expected to fund operations into 2024.

Headline financials

Total Revenue

$2.85M

Previous: $795K+259.0%
EPS (adj)

$0.38

Previous: -$0.33+216.5%
Capital Expenditures

$2.21M

No prior period
Free Cash Flow

-$16.6M

No prior period
Net Income

-$14.2M

Previous: -$7.81M-81.9%
Operating Income

-$14.2M

Previous: -$7.81M-81.8%
Gross Profit

$1.71M

Previous: -$5.17M+133.1%
Cash & Equivalents

$161M

No prior period
Total Assets

$188M

No prior period
Stock-Based Comp

$784K

No prior period

Revenue & EPS history

Tscan Therapeutics · Revenue · Quarterly

$2.85M

Q4 2021+259%vs Q4 2020
Beat estimate in 4 of 12 quarters(33%)
ActualEstimate

Revenue by segment

Tscan Therapeutics · $10.1M total across 1 segment · Q4 2021

  • Collaboration & License
    $10.1M

Forward guidance

TScan Therapeutics is focused on advancing its liquid and solid tumor programs, with key milestones expected in 2022, including initiating a Phase 1 trial for TSC-100, presenting preclinical data on the TSC-200 series, and submitting two IND applications.

Tailwinds

  • Initiate Phase 1 umbrella trial for TSC-100 in H1 2022.
  • Present initial clinical data from the liquid tumor program in H2 2022.
  • Present initial preclinical data on the TSC-200 series in H1 2022.
  • Submit two IND applications for the TSC-200 series in H2 2022.
  • Continue research into potential T cell focused COVID-19 vaccine constructs.

Headwinds

  • FDA placed a clinical hold on the IND for TSC-101 in January 2022.
  • The company is working with the FDA to resolve questions regarding potential off-tumor reactivity of TSC-101.
  • Resolution of the clinical hold on TSC-101 is necessary to open the TSC-101 arm of the ongoing trial.
  • Success of clinical trials and preclinical studies is subject to risks and uncertainties.
  • The COVID-19 pandemic could affect TScan's business and operations.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+1.6%

Avg return

Earnings day

+0.2%

Avg return

5 days after

-5.7%

Avg return

30 days after

60%

12 / 20 earnings

Positive

+32.4%

Q1 2023

Best reaction

-18.2%

Q2 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.3%-3.3%-18.9%
Q4 2025+4.9%+19.8%-2.4%
Q3 2025+0.8%-20.5%-17.2%
Q2 2025+3.1%+11.8%+14.9%
Q1 2025-4.6%+0.8%+18.3%
Q4 2024+2.6%+7.7%-7.1%
Q3 2024-7.9%-22.6%-47.0%
Q2 2024-1.0%-3.0%-3.9%
Q1 2024+16.3%+16.2%+14.9%
Q4 2023+1.6%-6.7%+0.9%
Q3 2023+3.0%+14.9%+50.8%
Q2 2023-4.2%-2.3%+12.1%
Q1 2023+32.4%+18.5%-14.4%
Q4 2022-8.5%-23.0%-33.3%
Q3 2022-0.4%+3.9%-20.6%
Q2 2022-10.8%-18.8%-20.5%
Q1 2022+10.6%+38.3%+80.0%
Q4 2021+7.8%-1.6%-37.8%
Q3 2021+2.2%-4.4%-28.0%
Q2 2021-18.2%-21.7%-53.7%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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