NASDAQ$STOK

Stoke Therapeutics Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

Stoke Therapeutics reported Q3 2025, revenue of $10.6M, a net loss of $38.3M.

For Q3 2025, Stoke Therapeutics reported revenue of $10.6M, a net loss of $38.3M. Management discussed operating trends, liquidity, and priorities as disclosed in the quarterly filing.

  • Revenue $10.6M.
  • Net loss $38.3M.
  • Stoke Therapeutics updated strategic and capital priorities in the filing.

Headline financials

Total Revenue

$10.6M

Previous: $4.89M+117.2%
EPS

-$0.65

Previous: -$0.47-38.3%
Capital Expenditures

-$438K

Previous: -$161K-172.0%
Free Cash Flow

-$38.8M

Previous: -$26.6M-45.9%
Net Income

-$38.3M

Previous: -$26.4M-45.1%
Operating Income

-$43.1M

Previous: -$30M-43.6%
Gross Profit

$10.6M

Previous: $4.89M+117.2%

Revenue & EPS history

Stoke Therapeutics · Revenue · Quarterly

$10.6M

Q3 2025+117.2%vs Q3 2024
Beat estimate in 11 of 15 quarters(73%)
ActualEstimate

Revenue by segment

Stoke Therapeutics · $3.27M total across 1 segment · Q4 2022

  • Acadia Pharm.
    $3.27M

Forward guidance

The filing discusses Stoke Therapeutics's outlook, capital deployment, and key risks without relying solely on numeric EPS guidance.

Tailwinds

  • Stoke Therapeutics cited execution on strategic priorities in the filing.
  • Balance sheet and liquidity support continued operations.
  • Pipeline milestones and partnerships remain key value drivers.

Headwinds

  • GAAP profitability remained under pressure in the quarter.
  • Macro, competitive, and cost pressures may affect margins.
  • Segment mix and one-time items can affect comparability.
  • Clinical or pre-commercial spend continues ahead of sustainable revenue.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+4.2%

Avg return

Earnings day

+4.9%

Avg return

5 days after

+3.1%

Avg return

30 days after

48%

13 / 27 earnings

Positive

+63.3%

Q4 2023

Best reaction

-20.0%

Q3 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-1.5%-2.6%-9.8%
Q4 2025-2.8%-1.3%+4.1%
Q3 2025-10.1%-11.7%+21.8%
Q1 2025+1.2%-1.6%+19.7%
Q4 2024-1.4%-9.4%-14.6%
Q3 2024+1.1%+6.0%-4.0%
Q2 2024-0.6%+1.5%+3.3%
Q1 2024-0.7%-4.5%+36.5%
Q4 2023+63.3%+114.3%+85.1%
Q3 2023+7.0%-1.2%+6.7%
Q2 2023-9.3%-11.1%-13.4%
Q1 2023+25.9%+28.1%+28.2%
Q4 2022+4.5%-1.0%-10.1%
Q3 2022-20.0%-35.9%-32.9%
Q2 2022+31.7%+28.6%-10.8%
Q1 2022+2.0%+17.3%+0.6%
Q4 2021-1.6%-2.1%+9.8%
Q3 2021+3.0%+9.4%-20.2%
Q2 2021-1.4%-2.4%-1.6%
Q1 2021+11.3%+9.9%+26.6%
Q4 2020+6.8%+1.5%-30.2%
Q3 2020-0.5%-7.8%+14.6%
Q2 2020+4.7%+8.5%+18.6%
Q1 2020+15.3%+18.9%-6.0%
Q4 2019-3.9%-2.3%-6.5%
Q3 2019-11.1%-21.7%-20.0%
Q2 2019+0.0%+5.3%-11.4%
Q1 2019
Q4 2018
Q3 2018
Q2 2018
Q1 2018

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