NASDAQ$SLNO

Soleno Therapeutics Inc · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

Soleno Therapeutics reported Q3 2025 product revenue of $66.0M with net income of $26.0M.

Product revenue reached $66.0 million following VYKAT XR launch after FDA approval in March 2025, versus no product revenue a year ago. Net income was $26.0 million as the rare-disease commercial ramp accelerated.

  • Q3 product revenue $66.0M (VYKAT XR launch).
  • Net income $26.0M.
  • First commercial quarter scale for VYKAT XR.
  • Launch execution and payer access critical.

Headline financials

Total Revenue

$66M

Previous: $0.00
EPS (adj)

$0.47

Previous: -$1.83+125.7%
Capital Expenditures

-$15K

Previous: -$191K+92.1%
Free Cash Flow

$26M

Previous: -$15.1M+272.0%
Net Income

$26M

Previous: -$76.6M+134.0%
Operating Income

$22.1M

Previous: -$80.2M+127.6%
Gross Profit

$64.9M

Previous: -$500K+13075.4%

Revenue & EPS history

Soleno Therapeutics · Revenue · Quarterly

$66M

Q3 2025
Beat estimate in 3 of 4 quarters(75%)
ActualEstimate

Forward guidance

The filing discusses Soleno Therapeutics's outlook, capital deployment, and key risks without relying solely on numeric EPS guidance.

Tailwinds

  • Soleno Therapeutics cited execution on strategic priorities in the filing.
  • Balance sheet and liquidity support continued operations.

Headwinds

  • Macro, competitive, and cost pressures may affect margins.
  • Segment mix and one-time items can affect comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

-1.8%

Avg return

Earnings day

-1.6%

Avg return

5 days after

-0.6%

Avg return

30 days after

38%

18 / 48 earnings

Positive

+15.2%

Q4 2014

Best reaction

-26.4%

Q3 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.0%-0.0%
Q4 2025-7.1%-8.1%-26.7%
Q3 2025-26.4%-27.5%-19.5%
Q2 2025-3.2%+2.7%-14.1%
Q1 2025+2.2%-0.3%+1.1%
Q4 2024-2.5%+10.2%+41.3%
Q3 2024+1.3%+4.9%-12.8%
Q2 2024-3.5%+0.2%+3.9%
Q1 2024-2.7%-6.0%-1.5%
Q4 2023-1.0%-2.8%-7.9%
Q3 2023-5.1%-4.8%+60.1%
Q2 2023+4.3%-2.1%-22.9%
Q1 2023-3.6%-1.2%+42.9%
Q4 2022+3.0%+16.3%+87.6%
Q3 2022+2.9%+5.2%-6.2%
Q2 2022+12.7%+11.0%-16.2%
Q1 2022-6.5%+10.5%+12.1%
Q4 2021-3.7%+4.9%-8.2%
Q3 2021-0.8%-1.9%-21.4%
Q2 2021+3.8%+4.7%-0.8%
Q1 2021-7.8%-6.1%-1.7%
Q4 2020+0.0%-47.5%-50.2%
Q3 2020-4.0%+3.5%-6.5%
Q2 2020+6.1%+4.5%+20.7%
Q1 2020-5.0%-3.2%-48.2%
Q4 2019+13.0%+1.1%-21.1%
Q3 2019+10.7%+6.4%+34.3%
Q2 2019-0.5%+3.1%-4.6%
Q1 2019-4.1%-4.1%+41.2%
Q4 2018-14.9%-10.3%-26.5%
Q3 2018+1.0%-4.3%-22.6%
Q2 2018-4.3%-5.1%-20.4%
Q1 2018+3.1%+8.6%+29.8%
Q4 2017-0.7%+1.5%-9.0%
Q3 2017-13.6%-22.7%-17.9%
Q2 2017+8.6%-6.2%+28.4%
Q1 2017+7.2%+1.4%-14.5%
Q4 2016+6.3%+0.1%-14.7%
Q3 2016-0.8%+0.0%-17.5%
Q2 2016-5.1%-2.4%+8.6%
Q1 2016-4.3%
Q4 2015-9.1%
Q3 2015-3.7%
Q2 2014-14.1%
Q2 2015-14.2%
Q1 2015-14.3%
Q4 2014+15.2%
Q3 2014+0.6%
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013

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