NASDAQ$SION

Sionna Therapeutics Inc · Q4 2025 earnings

Q4 2025 earnings · · Before market open

Briefing

SION reported Q4 2025, a net loss of $20.4M.

For Q4 2025, SION reported a net loss of $20.4M. Management discusses segment performance, capital allocation, and macro risks in the quarterly filing.

  • Net loss $20.4M.
  • SION MD&A covers liquidity, operating priorities, and sector risks.
  • SION MD&A covers liquidity, operating priorities, and sector risks.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$0.46

No prior period
Research and Development Expenses

$15.2M

No prior period
General and Administrative Expenses

$8.44M

No prior period
Total Operating Expenses

$23.6M

No prior period
Interest Income

$3.17M

No prior period
Net Income

-$20.4M

No prior period
Operating Income

-$23.6M

No prior period
Gross Profit

$0.00

No prior period

Revenue & EPS history

Sionna Therapeutics Inc · Revenue · Quarterly

$0

Q4 2025

Forward guidance

The quarterly filing discusses operating priorities, capital returns, and sector risks.

Tailwinds

  • MD&A highlights liquidity and core business trends.
  • Segment commentary supports the earnings narrative.

Headwinds

  • Macro or input-cost pressure may affect margins.
  • One-time items can affect YoY comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 4 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-0.4%

Avg return

Earnings day

+2.6%

Avg return

5 days after

+15.4%

Avg return

30 days after

40%

2 / 5 earnings

Positive

+13.4%

Q2 2025

Best reaction

-11.3%

Q1 2026

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-11.3%-12.4%-21.8%
Q4 2025-7.2%-1.7%+13.0%
Q3 2025-1.6%+0.4%+13.0%
Q2 2025+13.4%+17.8%+32.8%
Q1 2025+4.7%+9.0%+40.1%

Discussion

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