NASDAQ$SCYX

Scynexis Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Scynexis reported its full year 2024 financial results, including a net loss and a decrease in revenue compared to the previous year, while also providing updates on its clinical programs and cash runway.

SCYNEXIS reported a net loss of $21.3 million for the full year ended December 31, 2024, with total revenue of $3.7 million, a significant decrease from $140.1 million in 2023. The company ended 2024 with $75.1 million in cash, cash equivalents, and investments, projecting a cash runway into Q3 2026.

  • SCYNEXIS reported a full-year 2024 net loss of $21.3 million, or $0.44 basic loss per share.
  • Total revenue for the full year 2024 was $3.7 million, primarily from license agreement revenue.
  • Cash, cash equivalents, and investments totaled $75.1 million as of December 31, 2024, with a projected cash runway into Q3 2026.
  • The Phase 1 trial of SCY-247 was initiated in December 2024, with results expected in Q3 2025, and progress is being made to restart the Phase 3 MARIO study in Q2 2025.

Headline financials

Total Revenue

$3.75M

Previous: $5.8M-35.4%
EPS (adj)

-$0.44

Previous: -$0.39-12.8%
Net Income

-$21.3M

Previous: $67M-131.8%
Operating Income

-$37.1M

Previous: -$23.1M-60.9%
Cash & Equivalents

$16.1M

No prior period
Total Assets

$90.6M

No prior period

Revenue & EPS history

Scynexis · Revenue · Quarterly

$3.75M

Q4 2024-35.4%vs Q4 2023
Beat estimate in 5 of 13 quarters(38%)
ActualEstimate

Revenue by segment

Scynexis · $3.7M total across 1 segment · Q4 2024

  • License Agreement Revenue
    $3.7M

Forward guidance

SCYNEXIS anticipates key milestones in its clinical development programs and expects its current cash to fund operations into Q3 2026.

Tailwinds

  • Expectation of cash runway into Q3 2026.
  • Anticipated release of single and multiple ascending dose data from SCY-247 Phase 1 study in Q3 2025.
  • Anticipated lifting of the clinical hold of the Phase 3 MARIO study in Q2 2025.
  • SCY-247 has demonstrated highly encouraging preclinical results, highlighting its potential for clinical success.
  • Progress towards restarting the MARIO trial for invasive candidiasis.

Headwinds

  • Actual results may differ materially from forward-looking statements due to risks and uncertainties.
  • Risks inherent in regulatory and other costs in developing products.
  • Dependence on FDA's lifting of the clinical hold for the MARIO study restart.
  • No specific revenue guidance provided for future periods.
  • Continued net loss for the full year 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+12.3%

Avg return

Earnings day

+14.8%

Avg return

5 days after

+10.7%

Avg return

30 days after

53%

28 / 53 earnings

Positive

+619.7%

Q1 2026

Best reaction

-38.9%

Q1 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+619.7%+546.3%+353.1%
Q4 2025+2.9%+16.1%+14.6%
Q3 2025-5.6%-4.8%+4.0%
Q2 2025-5.3%-6.5%+32.5%
Q1 2025+28.6%+21.9%-5.3%
Q4 2024-1.0%-5.9%+1.0%
Q3 2024+0.0%-3.0%-9.8%
Q2 2024-5.4%-7.0%-31.7%
Q1 2024+1.6%+10.6%+20.3%
Q4 2023+4.2%+1.8%+8.1%
Q3 2023+0.3%-5.0%-2.1%
Q2 2023-8.0%-1.7%+13.0%
Q1 2023-3.8%+1.0%-4.5%
Q4 2022+24.8%+21.1%+7.1%
Q3 2022-14.7%-12.5%-5.4%
Q2 2022+0.7%-4.5%+2.1%
Q1 2022+10.7%+14.4%+4.3%
Q4 2021-14.5%-17.7%-45.1%
Q3 2021-5.9%+20.5%+27.7%
Q2 2021-2.2%-6.2%-5.8%
Q1 2021+11.5%+21.1%+5.6%
Q4 2020+1.0%+8.2%-2.0%
Q3 2020+13.3%+15.4%+34.0%
Q2 2020-2.0%-2.9%-28.0%
Q1 2020-0.3%-7.3%+1.2%
Q4 2019-22.7%-29.7%+1.0%
Q3 2019+3.5%-1.3%-34.9%
Q2 2019+2.8%+0.0%+2.8%
Q1 2019-2.6%-7.8%-24.0%
Q4 2018+19.0%+37.3%+45.2%
Q3 2018-2.3%-8.4%-41.2%
Q2 2018-6.1%-10.1%-12.2%
Q1 2018+8.5%+7.6%+52.5%
Q4 2017+2.7%+3.4%-11.0%
Q3 2017-9.3%-9.3%+12.9%
Q2 2017+1.9%-2.5%+35.6%
Q1 2017-38.9%-36.2%-37.4%
Q4 2016+9.0%+11.9%-5.2%
Q3 2016+4.5%+18.5%+14.3%
Q2 2016-1.9%+3.8%+41.8%
Q1 2016-4.3%
Q4 2015+0.7%
Q3 2015+6.9%
Q2 2015-3.2%
Q1 2015-4.3%
Q4 2014+5.1%
Q3 2014-0.8%
Q3 2013-0.8%
Q2 2013+7.7%
Q2 2014+7.7%
Q1 2014+5.7%
Q4 2013+5.7%
Q1 2013+5.7%

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