NASDAQ$SANA

Sana Biotechnology Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Sana Biotechnology reported financial results for Q4 2021 and provided business updates.

Sana Biotechnology reported a cash position of $746.9 million, research and development expenses of $108.5 million, and a net loss of $110.7 million for the fourth quarter of 2021. The company is progressing towards clinical trials for its multiple platforms and expects to file INDs for SC291 and SG295 in 2022.

  • Cash, cash equivalents, and marketable securities totaled $746.9 million.
  • Research and development expenses were $108.5 million.
  • Net loss was $110.7 million, or $0.60 per share.
  • The company expects to file INDs for leading CAR T ex vivo program, SC291, and in vivo program, SG295, in 2022.

Headline financials

EPS (adj)

-$0.65

Previous: -$2.98+78.2%
Capital Expenditures

$5.2M

Previous: $9.27M-43.9%
Free Cash Flow

-$115M

Previous: -$46.8M-146.2%
Net Income

-$111M

Previous: -$113M+2.2%
Operating Income

-$111M

Previous: -$113M+1.8%
Cash & Equivalents

$747M

Previous: $412M+81.3%
Total Assets

$1.13B

Previous: $730M+54.7%
Stock-Based Comp

$7.31M

Previous: $2.79M+162.0%

Revenue & EPS history

Sana · Revenue · Quarterly

$0

Q3 2025

Forward guidance

Sana Biotechnology plans to present data at multiple scientific conferences in 2022 and expects to file INDs for leading CAR T ex vivo program, SC291, and in vivo program, SG295, in 2022.

Tailwinds

  • Continued progress in building Sana’s hypoimmune ex vivo platform
  • Progressed Sana’s hypoimmune allogeneic CD19-targeted CAR T program, SC291; IND expected as early as this year
  • Progressed Sana’s in vivo CAR T program, SG295, utilizing a CD8-targeted fusosome to deliver a CD19-targeted CAR; IND expected as early as this year
  • Expanded Sana’s CAR T capability to potentially develop best-in-class, broadly accessible CAR T cell therapies
  • Progressed Sana’s stem cell-derived pancreatic beta cell program, SC451, with potential to treat type 1 diabetes

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-1.2%

Avg return

Earnings day

-2.0%

Avg return

5 days after

+4.1%

Avg return

30 days after

48%

10 / 21 earnings

Positive

+22.3%

Q2 2022

Best reaction

-25.3%

Q1 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+0.5%-15.3%-18.6%
Q3 2025-0.2%+3.9%+25.7%
Q2 2025+7.3%+14.0%+16.4%
Q1 2025+0.6%-1.7%+56.9%
Q4 2024-17.7%-16.6%-40.4%
Q3 2024-6.8%-14.2%-25.8%
Q1 2024-25.3%-21.2%-30.5%
Q4 2023+5.6%-8.1%-6.3%
Q3 2023-14.8%-10.3%-4.1%
Q2 2023-3.8%-1.3%-4.5%
Q1 2023+7.2%+11.8%+8.9%
Q4 2022+2.3%+2.3%+51.8%
Q3 2022-14.1%-21.6%-22.2%
Q2 2022+22.3%+18.3%-3.0%
Q1 2022-5.6%-11.9%-11.4%
Q4 2021+21.1%+19.5%+45.6%
Q3 2021-5.7%-3.3%-19.2%
Q2 2020+10.2%+9.5%+40.5%
Q2 2021+10.2%+9.5%+40.5%
Q1 2021-13.1%-1.9%+9.9%
Q4 2020-5.7%-4.1%-23.7%
Q3 2020
Q1 2020
Q4 2019

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