NASDAQ$RNAC

Selecta Biosciences Inc · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Selecta Biosciences reported Q1 2025 earnings with modest collaboration and grant revenue and a continued net loss as clinical development spending remained elevated.

Cartesian Therapeutics generated $1047000 in revenue in Q1 2025 from collaboration and grant funding while reporting a net loss of $17700000 as the company continued investing in the clinical development of Descartes-08 and other autoimmune programs.

  • Revenue totaled $1047000 from collaboration and grant funding sources.
  • Net loss was $17700000 with EPS of -0.68.
  • Operating loss reached $18200000 driven by R&D and administrative spending.
  • Cash, cash equivalents and restricted cash totaled $187200000 supporting ongoing clinical trials.

Headline financials

Total Revenue

$1.1M

Previous: $5.84M-81.2%
EPS

-$0.68

Previous: -$10.50+93.5%
Cash Balance

$187M

Previous: $2.03K+9237501.8%
Capital Expenditures

-$1.08M

Previous: -$602K-78.6%
Free Cash Flow

-$18.8M

Previous: -$57.4M+67.3%
Net Income

-$17.7M

Previous: -$56.8M+68.8%
Operating Income

-$21.9M

Previous: -$13.3M-64.0%
Gross Profit

$1.1M

Previous: $510K+115.7%

Revenue & EPS history

Selecta Biosciences · Revenue · Quarterly

$1.1M

Q1 2025-81.2%vs Q1 2024
Beat estimate in 7 of 13 quarters(54%)
ActualEstimate

Forward guidance

Cartesian Therapeutics expects existing capital to support continued clinical development of Descartes-08, including the Phase 3 AURORA trial in myasthenia gravis and expansion into additional autoimmune disease indications.

Tailwinds

  • Phase 3 AURORA trial progressing in myasthenia gravis.
  • Descartes-08 showed durable responses in prior clinical studies.
  • Pipeline expansion planned across multiple autoimmune indications.
  • Cash resources support ongoing clinical development programs.
  • Additional clinical milestones expected throughout 2025.

Headwinds

  • Company remains pre-commercial with limited revenue generation.
  • Operating losses continue due to heavy R&D investment.
  • Future results depend heavily on clinical trial outcomes.
  • Regulatory approval timelines remain uncertain.
  • Potential need for additional capital in the long term.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+0.3%

Avg return

Earnings day

-1.5%

Avg return

5 days after

+0.8%

Avg return

30 days after

36%

14 / 39 earnings

Positive

+43.0%

Q2 2022

Best reaction

-58.1%

Q3 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-3.9%+14.2%
Q4 2025+31.7%+7.9%-10.2%
Q3 2025-1.6%-4.8%-10.3%
Q2 2025-6.6%+0.4%-5.7%
Q1 2025-5.0%-4.2%+5.9%
Q3 2024-0.5%-18.8%+20.5%
Q2 2024-5.9%-3.8%-8.7%
Q1 2024-5.8%-7.6%+57.6%
Q4 2023-8.6%-16.0%-36.6%
Q3 2023+11.7%+11.7%-26.6%
Q2 2023+3.7%+7.3%+4.6%
Q1 2023-6.1%+2.6%+11.3%
Q4 2022-3.1%-5.0%-13.1%
Q3 2022+0.6%-4.9%-18.4%
Q2 2022+43.0%+55.2%+10.9%
Q1 2022+7.4%-0.6%+10.2%
Q4 2021-5.7%-16.6%-32.0%
Q3 2021-6.1%-8.1%-23.5%
Q2 2021+13.1%+8.9%+15.4%
Q1 2021-0.7%+3.7%+65.4%
Q4 2020+9.5%+16.7%+7.2%
Q3 2020-8.2%-8.2%-2.7%
Q2 2020-4.7%-3.6%-21.6%
Q1 2020+1.3%+4.2%+17.5%
Q4 2019-12.3%-35.6%-28.5%
Q3 2019-8.4%-9.7%-1.3%
Q2 2019-6.3%-11.5%+3.1%
Q1 2019-4.8%-8.4%-9.6%
Q4 2018+37.8%+21.6%+22.1%
Q3 2018-5.0%-2.8%-7.4%
Q2 2018+0.9%-1.5%+3.8%
Q1 2018+1.3%+10.4%+16.1%
Q4 2017-16.6%-22.8%+7.4%
Q3 2017-58.1%-59.9%-56.0%
Q2 2017-1.4%-7.1%+3.8%
Q1 2017-2.1%+3.2%+9.3%
Q4 2016+16.1%+18.9%+5.7%
Q3 2016+27.2%+17.9%+20.3%
Q2 2016-4.6%-1.7%+25.4%
Q3 2015
Q2 2015
Q1 2015

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