NASDAQ$RLAY

Relay Therapeutics Inc. · Q1 2026 earnings

Q1 2026 earnings · · Investor relations

Briefing

Relay Therapeutics reported Q1 2026 total revenue of $3.0M (-61% YoY) with a net loss of $73.3M, or $(0.41) per share.

For the quarter ended March 31, 2026, Relay Therapeutics posted total revenue of $3.0 million versus $7.7 million from collaboration funding. Net loss was $73.3 million, or $(0.41) per share, compared with a $(77.1) million loss and $(0.41) in Q1 2025. R&D expense was $70.6 million as precision oncology programs including RLY-2608 advanced.

  • Total revenue $3.0M; net loss $(73.3)M ($(0.41) EPS).
  • R&D $70.6M focused on PI3Kα and other oncology targets.
  • Cash runway and pipeline milestones key value drivers.
  • Platform-based drug discovery for allosteric inhibitors.
  • Collaboration revenue declined as programs shifted stage.

Headline financials

Total Revenue

$3M

Previous: $7.7M-61.0%
EPS (adj)

-$0.41

Previous: -$0.46+10.9%
Capital Expenditures

-$384K

Previous: -$384K+0.0%
Net Income

-$73.3M

Previous: -$77.1M+4.9%
Operating Income

-$78.6M

Previous: -$84.9M+7.4%

Revenue & EPS history

Relay Therapeutics · Revenue · Quarterly

$3M

Q1 2026-61%vs Q1 2025
Beat estimate in 6 of 14 quarters(43%)
ActualEstimate

Revenue by segment

Relay Therapeutics · $25.2M total across 1 segment · Q3 2023

  • License and Other Revenue
    $25.2M

Forward guidance

Relay discusses clinical trial enrollment, partnership options, and cash runway without numeric quarterly guidance.

Tailwinds

  • Loss per share stable despite lower collaboration revenue.
  • Interest income $5.4M offsets burn.
  • Differentiated allosteric oncology platform.

Headwinds

  • Minimal revenue; heavy R&D spend.
  • Clinical trial and regulatory binary risks.
  • Funding needs for late-stage development.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2026

Historical avgQ1 2026

+0.2%

Avg return

Earnings day

-0.4%

Avg return

5 days after

-0.5%

Avg return

30 days after

57%

13 / 23 earnings

Positive

+11.7%

Q4 2025

Best reaction

-19.5%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-0.7%-2.5%+11.1%
Q4 2025+11.7%+10.8%+4.8%
Q3 2025-7.4%-5.5%+17.6%
Q1 2025-4.8%-9.6%-2.4%
Q4 2024-13.3%-14.9%-27.5%
Q3 2024+3.2%+3.5%-22.5%
Q2 2024-6.8%-5.6%-8.6%
Q1 2024+5.7%+1.2%-3.8%
Q4 2023-4.6%-1.8%-25.7%
Q3 2023+10.1%+19.3%+27.4%
Q2 2023+7.8%+3.5%-3.2%
Q1 2023+0.5%-5.3%+2.3%
Q4 2022-3.6%-8.8%-13.5%
Q3 2022-4.3%-6.8%-12.4%
Q2 2022+3.8%-1.6%+31.7%
Q1 2022-19.5%-33.5%-31.6%
Q4 2021+11.5%+17.4%+40.1%
Q3 2021+1.7%+0.6%-19.6%
Q2 2021+1.0%+0.2%-1.7%
Q1 2021+5.7%+8.5%+23.9%
Q4 2020-2.3%+2.0%-13.5%
Q3 2020+0.5%+13.5%+5.7%
Q2 2020+8.0%+5.3%+8.5%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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