NASDAQ$REPL

Replimune Group Inc · Q4 2025 earnings

Q4 2025 earnings · · Before market open · Investor relations

Briefing

Replimune reported Q4 2025, net loss of $74.1M.

For Q4 2025, Replimune reported a net loss of $74.1M. Management discusses operating trends, capital, and sector risks in the quarterly filing.

  • Net loss $74.1M.
  • Replimune highlights liquidity, execution, and sector-specific risks in MD&A.
  • Replimune highlights liquidity, execution, and sector-specific risks in MD&A.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$3.07

No prior period
R&D Expenses

$54M

No prior period
SG&A Expenses

$25.4M

No prior period
Net Loss

-$74.1M

No prior period
Weighted Avg Shares

80.6M

No prior period
Net Income

-$74.1M

No prior period
Operating Income

-$262M

No prior period

Revenue & EPS history

Replimune · Revenue · Quarterly

$0

Q4 2025
Beat estimate in 2 of 3 quarters(67%)
ActualEstimate

Forward guidance

Clinical-stage biotech filers emphasize trial milestones, regulatory paths, and cash runway; product revenue is limited or absent.

Tailwinds

  • Pipeline progress and partnership optionality.
  • Cash balances funding operations into upcoming catalysts.
  • Regulatory designations where applicable.

Headwinds

  • Trial failure or regulatory delay risk.
  • Dilution from equity raises.
  • No near-term product revenue for most programs.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

+3.7%

Avg return

Earnings day

+2.3%

Avg return

5 days after

-1.0%

Avg return

30 days after

58%

18 / 31 earnings

Positive

+86.3%

Q4 2026

Best reaction

-11.8%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+86.3%+114.2%
Q3 2026+6.0%+11.1%+0.9%
Q2 2026-0.8%+6.4%+23.7%
Q1 2026-0.4%-4.5%+15.1%
Q4 2025+3.9%-0.5%+9.6%
Q3 2025+7.3%+9.7%-9.3%
Q2 2025-6.5%-13.6%-2.2%
Q1 2025+4.1%+5.8%+12.7%
Q4 2024+1.5%-11.5%+24.7%
Q3 2024+4.6%-3.6%+21.7%
Q2 2024-10.3%-13.7%-40.9%
Q1 2024-7.2%-14.2%-7.5%
Q4 2023+0.4%-0.2%+22.3%
Q3 2023-11.2%-13.0%-33.6%
Q2 2023-3.5%-6.1%+5.8%
Q1 2023+0.0%-2.6%-8.0%
Q4 2022+3.9%-0.6%+6.8%
Q3 2022-0.7%+0.5%-16.4%
Q2 2022+0.9%+0.2%-16.6%
Q1 2022-11.8%-12.9%-9.3%
Q4 2021+5.7%+5.8%+3.3%
Q3 2021+12.8%+7.2%-8.2%
Q2 2021-1.6%-6.2%-1.1%
Q1 2021+14.6%+10.2%+7.7%
Q4 2020+17.8%+19.5%+11.0%
Q3 2020-1.6%-1.4%-31.3%
Q2 2020-1.3%-27.9%-12.5%
Q1 2020-0.8%+6.3%+18.6%
Q4 2019+1.4%+1.4%-5.7%
Q3 2019+0.9%-2.7%-17.5%
Q2 2019+0.7%+8.9%+7.2%
Q4 2018
Q3 2018
Q2 2018
Q1 2018
Q4 2017

Discussion

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