NASDAQ$PLRX

Pliant Therapeutics Inc · Q2 2025 earnings

Q2 2025 earnings · · After market close · Investor relations

Briefing

Pliant Therapeutics Inc reported a net loss of $43.3 million for the second quarter of 2025.

The company reported a net loss of $43.3 million, or $0.71 per share, for the three months ended June 30, 2025, compared to a net loss of $55.9 million, or $0.92 per share, in the prior year period. Research and development expenses totaled $32.2 million and general and administrative expenses were $13.4 million. Cash, cash equivalents, restricted cash and short-term investments were $264.4 million at quarter end.

  • Net loss of $43.3 million for Q2 2025, improved from $55.9 million in Q2 2024
  • R&D expenses decreased to $32.2 million from $45.6 million year-over-year
  • Cash position of $264.4 million provides runway for ongoing development programs
  • Discontinued bexotegrast development in IPF following safety review

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$0.71

Previous: -$0.92+22.8%
Research and development expenses

$32.2M

No prior period
General and administrative expenses

$13.4M

No prior period
Interest and other income net

$3.1M

No prior period
Interest expense

$809K

No prior period
Total operating expenses

$45.6M

No prior period
Cash and short-term investments

$264M

No prior period
Net Income

-$43.3M

Previous: -$55.9M+22.5%
Operating Income

-$45.6M

Previous: -$60.6M+24.8%
Cash & Equivalents

$86.8M

Previous: $80.4M+8.0%
Total Assets

$300M

Previous: $484M-38.0%

Revenue & EPS history

Pliant Therapeutics · Revenue · Quarterly

$0

Q2 2025
Beat estimate in 3 of 14 quarters(21%)
ActualEstimate

Forward guidance

Company expects to continue incurring net losses while advancing early-stage pipeline programs following restructuring.

Tailwinds

  • Strong cash position of $264.4 million
  • Restructuring expected to extend cash runway

Headwinds

  • Continued net losses anticipated for foreseeable future
  • Discontinuation of lead program increases development risk

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports

Historical avg

-1.8%

Avg return

Earnings day

-2.4%

Avg return

5 days after

-4.2%

Avg return

30 days after

36%

9 / 25 earnings

Positive

+12.1%

Q3 2019

Best reaction

-11.7%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q4 2026+0.8%-4.2%-4.2%
Q3 2025+3.3%+17.6%-20.9%
Q1 2025-1.5%-2.9%-1.4%
Q4 2024-11.7%+17.4%-5.1%
Q3 2024-4.5%-12.0%-6.4%
Q2 2024-6.5%-9.6%-1.8%
Q1 2024-1.4%-1.2%-13.4%
Q4 2023-7.8%-4.8%-13.4%
Q3 2023-8.0%-12.4%-2.7%
Q2 2023+3.4%-0.9%-9.5%
Q1 2023+4.2%-0.0%+3.0%
Q4 2022-10.9%-9.4%-17.6%
Q3 2022-6.5%-6.7%-14.5%
Q2 2022+11.9%+12.6%+6.2%
Q1 2022-6.8%-1.8%+40.5%
Q4 2021+3.7%-9.9%-26.6%
Q3 2021-4.0%-3.2%-17.9%
Q2 2021-6.5%-12.4%-15.7%
Q1 2021-0.1%-14.7%-3.1%
Q4 2020+4.6%+2.5%-19.9%
Q3 2020+12.1%+9.9%+21.2%
Q3 2019+12.1%+9.9%+21.2%
Q2 2019-8.5%-8.2%-1.2%
Q4 2019-8.5%-8.2%-1.2%
Q2 2020-8.5%-8.2%-1.2%
Q1 2020
Q1 2019
Q1 2018

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