NASDAQ$PGEN

Precigen Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Precigen reported full-year 2025 total revenues of $5.8M and a net loss attributable to common shareholders of $429.6M, or $(1.37) per share.

The company recognized its first PAPZIMEOS product revenue ($3.4 million in Q4 2025) after FDA approval. Full-year net loss attributable to common shareholders was $429.6 million ($(1.37) per share) as commercial launch and R&D spending continued. Cash and investments were $100.4 million at year end.

  • PAPZIMEOS Q4 product revenue $3.4M.
  • Full-year net loss $(429.6)M; EPS $(1.37).
  • Permanent J-code J3404 effective April 2026.
  • Cash and investments $100.4M at 12/31/2025.

Headline financials

Total Revenue

$5.8M

Previous: $1.19M+387.4%
EPS (adj)

-$1.37

Previous: -$0.47-191.5%
Net Income

-$430M

Previous: -$126M-240.4%

Revenue & EPS history

Precigen · Revenue · Quarterly

$5.8M

Q4 2025+387.4%vs Q4 2024
Beat estimate in 5 of 14 quarters(36%)
ActualEstimate

Revenue by segment

Precigen · $18.4M total across 3 segments · Q4 2020

  • Service revenue
    $14.3M+18.1%
  • Product revenue
    $3.95M-25.4%
  • Collab & licensing
    $148K-44.6%

Forward guidance

The quarterly filing discusses operating priorities, capital returns, and sector risks; numeric multi-quarter bridges vary by issuer.

Tailwinds

  • MD&A highlights liquidity, capital, and core business trends.
  • Segment or product commentary supports the earnings narrative.

Headwinds

  • Macro, rates, or input costs may pressure near-term margins.
  • One-time items can affect year-over-year comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports

Historical avg

+0.4%

Avg return

Earnings day

+1.6%

Avg return

5 days after

+1.4%

Avg return

30 days after

50%

26 / 52 earnings

Positive

+31.0%

Q2 2023

Best reaction

-38.9%

Q4 2018

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q1 2026+1.7%-0.2%
Q3 2025+25.6%+9.3%-4.4%
Q2 2025+6.1%+63.9%+110.6%
Q1 2025-2.8%-5.7%+0.7%
Q4 2024+0.6%-4.5%-22.3%
Q3 2024-10.4%-13.0%-26.1%
Q1 2024+6.7%+2.2%+25.9%
Q4 2023+3.6%+0.7%-5.0%
Q3 2023-13.5%-19.8%-6.3%
Q2 2023+31.0%+43.1%+39.7%
Q1 2023-9.5%-4.0%-6.3%
Q4 2022+16.4%-6.0%-15.5%
Q3 2022+11.2%+18.1%-2.5%
Q2 2022+11.6%+14.5%+11.1%
Q1 2022+3.2%+8.0%+23.2%
Q4 2021-1.3%-10.2%-6.2%
Q3 2021-7.1%-11.8%-33.3%
Q2 2021+8.6%+10.4%+10.6%
Q1 2021-0.2%+5.7%+9.5%
Q4 2020+1.7%+0.1%-18.4%
Q3 2020+22.2%+20.4%+69.7%
Q2 2020-5.7%-8.8%-1.0%
Q1 2020-5.9%-4.2%-4.7%
Q4 2019-14.5%-19.0%-27.4%
Q3 2019-1.1%+2.0%+6.3%
Q2 2019-7.2%-10.3%-23.4%
Q1 2019-1.1%+0.7%+22.2%
Q4 2018-38.9%-39.4%-36.5%
Q3 2018-19.3%-24.4%-32.1%
Q2 2018-5.7%-4.6%-2.9%
Q1 2018-19.5%-13.0%-9.3%
Q4 2017+23.6%+20.9%+17.7%
Q3 2017-25.3%-19.7%-15.9%
Q2 2017-5.2%-4.0%-15.0%
Q1 2017+21.5%+32.0%+15.0%
Q4 2016+5.8%+2.1%-11.0%
Q3 2016+14.1%+24.0%+15.7%
Q2 2016+3.3%+4.5%+0.9%
Q1 2016-5.1%
Q4 2015-0.1%
Q3 2015+9.7%
Q2 2015-17.8%
Q1 2015+3.2%
Q4 2014+17.3%
Q3 2014-3.9%
Q2 2014-2.9%
Q1 2013+2.9%
Q1 2014-11.7%
Q4 2013+5.5%
Q3 2012+3.6%
Q3 2013+3.6%
Q2 2013-7.8%
Q4 2012
Q2 2012
Q1 2012

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