NASDAQ$OPK

OPKO Health Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

OPKO Health's financial performance declined due to decreased COVID-19 testing volume and increased expenses, despite growth in international pharmaceutical businesses.

OPKO Health reported a decrease in consolidated total revenues to $401.3 million compared to $494.6 million for the same period in 2020. The company experienced an operating loss of $63.1 million, a net loss of $73.8 million, and a diluted loss per share of $0.11. The decline was primarily due to decreased COVID-19 testing volume and increased investments in BioReference Laboratories' base business and digital health activities.

  • NGENLA® received regulatory approvals in Europe, Japan, Australia, and Canada.
  • RAYALDEE® was launched in Germany by Vifor Fresenius Medical Care Renal Pharma.
  • Topline results were reported from a Phase 2 clinical trial evaluating RAYALDEE as a treatment for symptomatic COVID-19 outpatients.
  • A definitive agreement was signed for Sema4 Holdings Corp. to acquire GeneDx, Inc.

Headline financials

Total Revenue

$401M

Previous: $495M-18.9%
EPS (adj)

-$0.11

Previous: $0.05-320.0%
Net Income

-$73.8M

Previous: $32.3M-328.5%
Operating Income

-$63.1M

Previous: $49.3M-228.0%
Gross Profit

$401M

Previous: $495M-18.9%
Cash & Equivalents

$135M

Previous: $72.2M+86.6%
Total Assets

$2.4B

Previous: $2.47B-3.0%
Stock-Based Comp

$3.7M

Previous: $2.17M+70.6%

Revenue & EPS history

OPKO Health · Revenue · Quarterly

$401M

Q4 2021-18.9%vs Q4 2020
Beat estimate in 10 of 16 quarters(63%)
ActualEstimate

Revenue by segment

OPKO Health · $398M total across 2 segments · Q4 2021

  • Services
    $363M
  • Products
    $35.3M

Forward guidance

OPKO Health's forward guidance was not explicitly provided in the press release. Therefore, this section summarizes key developments and expectations based on the information available.

Tailwinds

  • Regulatory approvals for NGENLA® in key markets.
  • Commercial launch of RAYALDEE® in Germany.
  • Potential for Sema4 and GeneDx to become a leading provider of genomic clinical testing.
  • Increased demand for COVID-19 PCR tests due to the Omicron variant.
  • FDA approval of the Premarket Approval Application (PMA) of the 4Kscore® Test.

Headwinds

  • Complete Response Letter from the FDA for somatrogon in the U.S.
  • Decrease in COVID-19 testing volume.
  • Negative impact on RAYALDEE® sales due to COVID-19 pandemic.
  • Operating loss for the fourth quarter of 2021.
  • Net loss for the fourth quarter of 2021.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-0.7%

Avg return

Earnings day

+0.3%

Avg return

5 days after

-0.2%

Avg return

30 days after

44%

27 / 61 earnings

Positive

+26.8%

Q1 2018

Best reaction

-17.7%

Q3 2017

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+0.8%-8.3%+19.2%
Q4 2025+2.5%+0.0%-6.7%
Q3 2025-2.9%-4.3%-2.9%
Q1 2025-2.2%-7.2%-1.4%
Q4 2024+6.7%+19.0%+4.3%
Q3 2024+3.4%+9.5%+8.2%
Q2 2024+6.7%+11.9%+16.4%
Q1 2024-5.3%-3.0%+1.5%
Q4 2023-1.1%-1.0%+20.0%
Q3 2023-0.7%-6.7%+18.5%
Q2 2023+13.1%+6.8%+2.8%
Q1 2023+15.0%+26.5%-1.4%
Q4 2022+0.0%+7.5%+22.6%
Q3 2022-14.8%-9.3%-25.8%
Q2 2022-6.6%+2.9%-12.7%
Q1 2022+11.8%+15.6%+8.4%
Q4 2021+7.4%+3.7%+17.8%
Q3 2021+5.9%+16.2%+15.4%
Q2 2021-11.6%-7.2%-0.8%
Q1 2021-3.7%-4.2%-10.5%
Q4 2020-13.6%-18.0%-12.9%
Q3 2020-12.0%-11.0%+3.3%
Q2 2020-11.1%-7.4%-42.3%
Q1 2020-15.2%+3.9%+2.2%
Q4 2019+3.6%+12.2%+0.7%
Q3 2019-2.0%-2.6%+5.3%
Q2 2019-2.1%-6.2%-4.6%
Q1 2019-16.1%-14.9%-22.1%
Q4 2018-9.9%-5.7%-7.8%
Q3 2018+6.7%-7.4%-6.0%
Q2 2018-0.4%-1.6%+1.5%
Q1 2018+26.8%+37.8%+23.5%
Q4 2017-0.6%+0.9%-6.5%
Q3 2017-17.7%-20.1%-20.2%
Q2 2017+1.7%-1.3%-1.6%
Q1 2017-3.4%-0.8%-13.7%
Q4 2016-11.5%-9.3%-4.6%
Q3 2016-6.6%-3.4%+11.8%
Q2 2016+0.3%-0.5%-5.1%
Q1 2016+6.7%
Q4 2015+0.4%
Q3 2015+7.6%
Q2 2015-13.7%
Q1 2015+4.8%
Q4 2014-2.7%
Q3 2014+2.5%
Q2 2014-4.0%
Q1 2014+8.4%
Q4 2013-0.6%
Q3 2013-1.4%
Q2 2013+3.7%
Q1 2013+3.4%
Q4 2011-4.0%
Q1 2011+1.3%
Q1 2012+2.7%
Q4 2009-2.6%
Q3 2011-2.3%
Q2 2011-3.3%
Q4 2010-3.3%
Q3 2010+0.7%
Q1 2010+9.1%

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