NASDAQ$OMGAQ

Omega Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Omega Therapeutics announced financial results for the fourth quarter and full year ended December 31, 2021, and outlined key corporate objectives for 2022.

Omega Therapeutics reported its Q4 2021 financial results, with a net loss of $20.9 million. The company had $225.3 million in cash, cash equivalents, and marketable securities as of December 31, 2021. They are planning to submit an Investigational New Drug application (IND) for OTX-2002 and nominate two OEC candidates in the first half of 2022.

  • IND application for OTX-2002 for c-Myc Driven Hepatocellular Carcinoma is on track to be submitted in the first half of 2022.
  • Additional Omega Epigenomic Controller™ Development Candidates are targeted to be announced in the first half of 2022.
  • The company had a strong balance sheet to fund the pipeline of Omega Epigenomic Controllers with $225.3 million in cash, cash equivalents and marketable securities as of December 31, 2021.
  • An abstract was selected for a poster presentation at the upcoming AACR 2022 Annual Meeting, highlighting the mechanism of action of OTX-2002 and its potential as a differentiated and viable approach to the treatment of HCC.

Headline financials

Total Revenue

$144K

No prior period
EPS (adj)

-$0.44

Previous: -$0.30-44.7%
Capital Expenditures

$200K

No prior period
Free Cash Flow

-$16.2M

No prior period
Net Income

-$20.9M

Previous: -$9.47M-120.3%
Operating Income

-$20.7M

Previous: -$9.24M-123.6%
Gross Profit

-$240K

Previous: -$21.1M+98.9%
Cash & Equivalents

$186M

No prior period
Total Assets

$233M

No prior period
Stock-Based Comp

$1.18M

No prior period

Revenue & EPS history

Omega Therapeutics · Revenue · Quarterly

$144K

Q4 2021
Beat estimate in 9 of 11 quarters(82%)
ActualEstimate

Forward guidance

Omega Therapeutics is focused on advancing its pipeline and platform in 2022 with several key milestones.

Tailwinds

  • Complete IND-enabling studies for OTX-2002 and file the Company’s first IND to the U.S. Food and Drug Administration (FDA) during the first half of 2022.
  • Declare two OEC development candidates in the first half of 2022.
  • Target submission of an additional IND application in the second half of 2022 or early 2023.
  • Continue to develop the OMEGA Epigenomic Programming platform and investigate additional development programs to expand pipeline.
  • Publish and present relevant preclinical and early clinical data supporting programs and platform development.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 9 quarterly earnings reports

Historical avg

-5.1%

Avg return

Earnings day

-8.9%

Avg return

5 days after

-12.9%

Avg return

30 days after

47%

7 / 15 earnings

Positive

+14.2%

Q1 2023

Best reaction

-47.5%

Q4 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-47.5%-25.0%-44.8%
Q3 2024-22.6%-30.7%-9.2%
Q2 2024-0.6%+0.0%-11.3%
Q1 2024-16.7%-16.1%-17.3%
Q4 2023-9.9%-15.3%-36.6%
Q3 2023-3.4%+5.1%+28.7%
Q2 2023+2.4%-14.2%-23.8%
Q1 2023+14.2%+9.1%+4.4%
Q4 2022+5.6%+7.0%-6.7%
Q3 2022-3.8%
Q2 2022+9.3%
Q1 2022+0.3%
Q4 2021-6.4%
Q3 2021+1.5%
Q2 2021+0.9%
Q1 2021
Q4 2020
Q3 2020
Q2 2020
Q1 2020

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