NASDAQ$OBIO

Orchestra Biomed Holdings In · Q3 2025 earnings

Q3 2025 earnings · · After market close · Investor relations

Briefing

Orchestra BioMed reported Q3 2025, revenue of $2.1M, net loss of $15M.

For Q3 2025, Orchestra BioMed reported revenue of $2.1M, a net loss of $15M. Management discusses segment performance, capital allocation, and sector risks in the quarterly filing.

  • Revenue $2.1M.
  • Net loss $15M.
  • Orchestra BioMed MD&A covers liquidity, credit, and operating priorities.

Headline financials

Total Revenue

$861K

Previous: $987K-12.8%
EPS

-$0.40

Previous: -$0.41+2.4%
Capital Expenditures

-$456K

Previous: -$183K-149.2%
Free Cash Flow

-$21.3M

Previous: -$15.6M-36.4%
Net Income

-$20.8M

Previous: -$15.4M-35.0%
Operating Income

-$20.3M

Previous: -$16.3M-24.3%
Gross Profit

$812K

Previous: $919K-11.6%
Cash & Equivalents

$42M

No prior period
Total Assets

$105M

No prior period

Revenue & EPS history

Orchestra Biomed · Revenue · Quarterly

$861K

Q3 2025-12.8%vs Q3 2024
Beat estimate in 8 of 13 quarters(62%)
ActualEstimate

Revenue by segment

Orchestra Biomed · $2.64M total across 2 segments · Q4 2024

  • Partnership revenue
    $2.01M-4.8%
  • Product revenue
    $633K-3.2%

Forward guidance

Clinical-stage or royalty biotech outlook centers on trial readouts, partnerships, and cash runway.

Tailwinds

  • Pipeline milestones and collaboration optionality.
  • Cash and marketable securities fund operations.

Headwinds

  • Trial failure or delay risk.
  • Dilution from future financings.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q3 2025

Historical avgQ3 2025

+4.3%

Avg return

Earnings day

+2.2%

Avg return

5 days after

+5.7%

Avg return

30 days after

63%

12 / 19 earnings

Positive

+30.5%

Q4 2022

Best reaction

-6.0%

Q4 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+3.8%-4.9%+4.1%
Q4 2025+4.7%+4.9%-2.0%
Q3 2025+4.6%+12.4%+9.1%
Q2 2025-2.6%+1.8%+4.0%
Q1 2025+0.3%-5.9%+16.6%
Q4 2024-6.0%-4.4%-11.1%
Q3 2024-1.0%-4.7%-12.9%
Q2 2024-3.7%+3.7%-8.1%
Q1 2024+10.4%+10.6%+68.6%
Q4 2023+0.2%-5.9%-16.5%
Q3 2023+29.6%+28.8%+58.3%
Q2 2023+5.3%-0.5%+9.2%
Q1 2023+2.5%+15.3%-16.8%
Q4 2022+30.5%-12.1%-1.6%
Q3 2022+0.3%-0.4%+0.1%
Q2 2022+0.0%+0.1%+0.2%
Q4 2021+0.0%+0.2%+0.4%
Q1 2022+0.0%+0.2%+0.4%
Q1 2021+3.7%+1.8%+6.2%

Discussion

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