NASDAQ$NUVL

Nuvalent Inc · Q1 2022 earnings

Q1 2022 earnings · · Investor relations

Briefing

Nuvalent reported first quarter 2022 financial results and highlighted pipeline and business progress.

Nuvalent reported a net loss of $17.5 million, or $0.36 per share, for the first quarter of 2022. The company ended the quarter with $272.7 million in cash, cash equivalents, and marketable securities.

  • Enrollment is progressing well in the Phase 1 portion of the ARROS-1 Phase 1/2 trial of NVL-520 for advanced ROS1-positive NSCLC and other solid tumors.
  • The IND for NVL-655 was cleared, and the company is on track for planned initiation of the ALKOVE-1 Phase 1/2 study for advanced ALK-positive NSCLC and other solid tumors in the second quarter of 2022.
  • Nuvalent expects to select development candidates for its programs directed toward ALK IXDN compound resistance mutations and HER2 Exon 20 insertions in 2022.
  • Anna Protopapas was appointed as Chair of the Board of Directors in March 2022.

Headline financials

EPS (adj)

-$0.36

Previous: -$2.20+83.6%
Research and development expenses

$12.7M

No prior period
General and administrative expenses

$5M

No prior period
Net Income

-$17.5M

Previous: -$6.79M-158.6%
Operating Income

-$17.7M

Previous: -$6.16M-187.0%
Cash & Equivalents

$273M

Previous: $14.4M+1793.9%
Total Assets

$277M

No prior period
Stock-Based Comp

$2.21M

Previous: $65K+3292.3%

Revenue & EPS history

Nuvalent · Revenue · Quarterly

$6M

Q3 2025

Forward guidance

Nuvalent expects the existing cash, cash equivalents, and marketable securities to be sufficient to fund its planned operations into 2024.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 17 quarterly earnings reports · overlaid with Q1 2022

Historical avgQ1 2022

-0.0%

Avg return

Earnings day

-0.8%

Avg return

5 days after

-7.7%

Avg return

30 days after

38%

8 / 21 earnings

Positive

+14.6%

Q4 2021

Best reaction

-5.0%

Q3 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025-0.5%-4.1%-7.5%
Q3 2025-5.0%-11.6%+6.2%
Q1 2025+3.2%+3.7%+10.2%
Q4 2024-2.8%-7.0%-5.2%
Q3 2024-4.3%-8.0%-8.0%
Q1 2024-3.1%+0.7%+17.2%
Q4 2023-1.4%+0.6%-13.3%
Q3 2023+3.7%+5.0%+38.8%
Q2 2023-1.1%-3.1%+9.2%
Q1 2023-2.5%-1.1%+3.5%
Q4 2022+8.3%+4.7%+0.9%
Q3 2022+1.0%+2.9%-2.1%
Q2 2022+4.5%+9.3%+13.1%
Q1 2022-0.7%+7.3%+16.1%
Q4 2021+14.6%+20.2%-8.1%
Q3 2020+1.3%-14.7%-2.4%
Q3 2021+1.3%-10.4%-20.1%
Q2 2020-4.3%-2.9%-52.6%
Q1 2021-4.3%-2.9%-52.6%
Q2 2021-4.3%-2.9%-52.6%
Q4 2020-4.3%-2.9%-52.6%
Q1 2020

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