NASDAQ$MRSN

Mersana Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Mersana's financial position strengthened with strategic partnerships and clinical advancements.

Mersana Therapeutics reported its Q4 2021 financial results, highlighting progress in its UpRi development plan, advancements in its ADC pipeline, and a strengthened financial position through strategic partnerships and financing activities.

  • UpRi development on track for potential BLA submission in 2023 based on UPLIFT data.
  • UP-NEXT trial to initiate in Q2 2022, and UPGRADE on track for 2H 2022 interim data readout.
  • XMT-1660 and XMT-2056 expected to enter clinic mid-2022.
  • Janssen collaboration validates Dolasynthen platform and ADC innovation.

Headline financials

Total Revenue

$11K

Previous: $10K+10.0%
EPS (adj)

-$0.68

Previous: -$0.42-61.9%
Capital Expenditures

$155K

Previous: $188K-17.6%
Free Cash Flow

-$42.6M

Previous: -$17.5M-143.1%
Net Income

-$49M

Previous: -$28.8M-69.8%
Gross Profit

-$37.4M

Previous: -$22.8M-63.5%
Cash & Equivalents

$178M

Previous: $255M-30.2%
Total Assets

$206M

Previous: $273M-24.6%
Stock-Based Comp

$4.86M

Previous: $1.99M+144.3%

Revenue & EPS history

Mersana · Revenue · Quarterly

$11K

Q4 2021+10%vs Q4 2020
Beat estimate in 6 of 16 quarters(38%)
ActualEstimate

Forward guidance

Mersana is focused on advancing clinical trials, expanding its ADC pipeline, and leveraging its technology platforms for strategic partnerships.

Tailwinds

  • Completing enrollment for UPLIFT trial in Q3 2022.
  • Initiating UP-NEXT trial in Q2 2022.
  • Anticipating interim data readout from UPGRADE trial in 2H 2022.
  • Advancing XMT-1660 and XMT-2056 into the clinic by mid-2022.
  • Leveraging ADC expertise and Dolasynthen platform through Janssen collaboration.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 12 quarterly earnings reports

Historical avg

+1.4%

Avg return

Earnings day

+2.5%

Avg return

5 days after

+1.3%

Avg return

30 days after

47%

17 / 36 earnings

Positive

+38.9%

Q2 2022

Best reaction

-20.3%

Q1 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025
Q3 2025+2.4%+0.8%+3.0%
Q2 2025+11.6%+22.3%+18.6%
Q1 2025-18.5%-0.2%-3.6%
Q4 2024-8.3%+3.6%-36.7%
Q3 2024+14.5%-3.7%-1.8%
Q2 2024-13.4%-7.2%+25.2%
Q1 2024-20.3%-23.8%-37.4%
Q4 2023+27.4%+33.8%+4.8%
Q3 2023-6.5%-12.9%+46.8%
Q2 2023+0.0%+4.2%+6.7%
Q1 2023+8.9%+8.2%+16.4%
Q4 2022+7.0%+4.4%-26.3%
Q3 2022-11.0%
Q2 2022+38.9%
Q1 2022-11.2%
Q4 2021+14.4%
Q3 2021-1.1%
Q2 2021-2.1%
Q1 2021-5.3%
Q4 2020+7.7%
Q3 2020-4.2%
Q2 2020-1.9%
Q1 2020-3.1%
Q4 2019+3.5%
Q3 2019+7.0%
Q2 2019+2.3%
Q1 2019+14.3%
Q4 2018+4.0%
Q3 2018+7.5%
Q2 2018+0.0%
Q1 2018-3.7%
Q1 2016-8.9%
Q3 2016-4.5%
Q3 2017-5.1%
Q4 2016+3.9%
Q2 2016+3.9%
Q1 2017

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