NASDAQ$KURA

Kura Oncology Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Kura Oncology reported its fourth quarter and full year 2024 financial results.

Kura Oncology reported positive topline results from its KOMET-001 registrational trial, achieving its primary endpoint, and announced alignment with the FDA and EMA on key aspects of the KOMET-017 protocol for potential U.S. accelerated approval. The company also reported a significant increase in collaboration revenue due to its partnership with Kyowa Kirin.

  • KOMET-001 registrational trial in R/R NPM1-mutant AML achieved its primary endpoint.
  • Alignment reached with FDA and EMA on key aspects of the KOMET-017 protocol, including use of MRD-negative CR endpoint for potential U.S. accelerated approval pathway in frontline intensive chemotherapy trial.
  • Collaboration revenue from the Kyowa Kirin partnership for Q4 2024 was $53.9 million, compared to no revenue in 2023.
  • Net loss for Q4 2024 was $19.2 million, an improvement from a net loss of $42.8 million in Q4 2023.

Headline financials

Total Revenue

$53.9M

Previous: $0.00
EPS (adj)

-$0.22

Previous: -$0.55+60.0%
R&D Expenses

$52.3M

Previous: $32.5M+60.7%
SG&A Expenses

$24.1M

Previous: $14.2M+69.2%
Total Operating Expenses

$76.3M

Previous: $46.8M+63.2%
Share-based Compensation

$8.6M

Previous: $7.2M+19.4%
Other Income, Net

$5.26M

Previous: $3.98M+32.2%
Income Tax Expense

$2.02M

Previous: $0.00
Capital Expenditures

-$372K

Previous: -$16K-2225.0%
Net Income

-$19.2M

Previous: -$42.8M+55.1%
Operating Income

-$22.5M

Previous: -$46.8M+52.0%
Gross Profit

$53.7M

Previous: -$214K+25183.6%
R&D Expense

$52.3M

Previous: $32.5M+60.7%

Revenue & EPS history

Kura Oncology · Revenue · Quarterly

$53.9M

Q4 2024
Beat estimate in 1 of 7 quarters(14%)
ActualEstimate

Forward guidance

Kura Oncology anticipates submitting an NDA for ziftomenib in R/R NPM1-m AML in Q2 2025 and initiating two independent Phase 3 registration-enabling trials in 1L AML in H2 2025. The company expects its current cash to fund operations into 2027.

Tailwinds

  • Submit an NDA for ziftomenib in R/R NPM1-m AML in the second quarter of 2025.
  • Present topline data from KOMET-001 Phase 2 registration-directed trial in R/R NPM1-m AML in the second quarter of 2025.
  • Initiate the KOMET-015 trial evaluating ziftomenib and imatinib in patients with advanced GIST in the first half of 2025.
  • Initiate two independent Phase 3 registration-enabling trials in 1L intensive (KOMET-017-IC) and non-intensive (KOMET-017-NIC) AML in the second half of 2025.
  • Current cash, cash equivalents and short-term investments are sufficient to fund operating expenses into 2027, supported by anticipated collaboration funding.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+0.5%

Avg return

Earnings day

+1.3%

Avg return

5 days after

+0.9%

Avg return

30 days after

53%

21 / 40 earnings

Positive

+22.4%

Q2 2016

Best reaction

-19.3%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.7%-2.9%-6.8%
Q4 2025-0.5%+8.3%+0.7%
Q3 2025+2.0%+0.9%+22.6%
Q2 2025-7.0%+8.9%+37.9%
Q1 2025-0.6%-13.0%-12.3%
Q4 2024-1.5%-5.7%-9.3%
Q3 2024-0.9%+4.1%-40.2%
Q1 2024+1.7%+3.9%+1.6%
Q4 2023+3.1%+4.1%+2.8%
Q3 2023+12.8%+16.0%+24.7%
Q2 2023+7.1%+1.3%-2.0%
Q1 2023+8.8%+11.1%+14.6%
Q4 2022-2.2%-0.3%-1.4%
Q3 2022-7.2%-14.8%+2.6%
Q2 2022+1.1%+4.2%-0.8%
Q1 2022-11.8%-22.5%-8.7%
Q4 2021+14.6%+13.6%+12.9%
Q3 2021+6.5%+0.2%-32.6%
Q2 2021+0.8%-3.4%+8.0%
Q1 2021+2.5%-1.5%-16.6%
Q4 2020-19.3%-10.0%-17.8%
Q3 2020+9.2%+20.0%+12.3%
Q2 2020+15.7%+17.0%+36.7%
Q1 2020+5.3%+7.0%+18.1%
Q4 2019-4.3%-3.8%-26.1%
Q3 2019-4.4%+1.1%-1.0%
Q2 2019+0.8%-1.2%-20.6%
Q1 2019+5.9%+4.1%+3.0%
Q4 2018-9.0%-1.7%+12.3%
Q3 2018+5.4%+9.4%+19.3%
Q2 2018-13.7%-11.2%-7.0%
Q1 2018-0.6%+4.7%+3.5%
Q4 2017-1.3%-13.5%-23.8%
Q3 2017-6.4%+11.1%-4.4%
Q2 2017-13.0%-38.2%-32.9%
Q1 2017+0.0%+2.8%-13.9%
Q4 2016-8.5%-6.3%+6.9%
Q3 2016+6.0%+25.3%+27.7%
Q2 2016+22.4%+20.1%+43.5%
Q4 2015+0.5%
Q4 2014
Q2 2014
Q1 2014
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q4 2012
Q3 2012
Q2 2012
Q1 2012
Q4 2011
Q3 2011
Q2 2011
Q1 2011
Q4 2010
Q3 2010
Q2 2010
Q1 2010

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