NASDAQ$KROS

Keros Therapeutics Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Keros reported financial results for Q4 and full year 2023, highlighting clinical progress across the pipeline and advancement of KER-065 into Phase 1 trial.

Keros Therapeutics reported a net loss of $40.2 million for the fourth quarter of 2023, driven by increased research and development expenses and investments to support clinical and corporate goals. The company's cash and cash equivalents totaled $331.1 million as of December 31, 2023, which, along with proceeds from a January 2024 offering, is expected to fund operations into 2027.

  • Keros made continued clinical progress across its pipeline in 2023.
  • Phase 2 clinical trial evaluating KER-012 in patients with pulmonary arterial hypertension (PAH) was commenced.
  • Exciting data was presented from two ongoing Phase 2 clinical trials of KER-050 in patients with myelodysplastic syndromes (MDS) and myelofibrosis.
  • KER-065 advanced into a Phase 1 healthy volunteer clinical trial at the beginning of 2024.

Headline financials

Total Revenue

$143K

No prior period
EPS (adj)

-$1.34

Previous: -$1.09-22.9%
Capital Expenditures

-$541K

Previous: $351K-254.1%
Free Cash Flow

-$26M

Previous: -$21.8M-19.3%
Net Income

-$40.2M

Previous: -$29.7M-35.4%
Operating Income

-$46.5M

Previous: -$32M-45.4%
Gross Profit

-$104K

No prior period
R&D Expense

$37.5M

No prior period
Stock-Based Comp

$7.32M

Previous: $4.75M+54.3%

Revenue & EPS history

Keros · Revenue · Quarterly

$143K

Q4 2023
Beat estimate in 2 of 5 quarters(40%)
ActualEstimate

Forward guidance

Keros anticipates several program milestones, including engaging with regulators on the Phase 3 trial design for KER-050 in MDS, reporting additional data from KER-050 trials in MDS and myelofibrosis, providing an update on KER-012 enrollment in PAH patients, reporting initial data from the KER-012 biomarker trial in chronic heart failure patients, and reporting initial data from the KER-065 Phase 1 trial in healthy volunteers.

Tailwinds

  • Engage with regulators on the design of the planned Phase 3 clinical trial of KER-050 in patients with MDS in the first half of 2024
  • Report additional data from Part 2 of the ongoing Phase 2 clinical trial of KER-050 in patients with MDS in the second and fourth quarters of 2024
  • Report additional data from the ongoing Phase 2 clinical trial of KER-050 in patients with myelofibrosis in the second and fourth quarters of 2024
  • Provide an update on enrollment of the ongoing Phase 2 clinical trial evaluating KER-012 in patients with PAH (the “TROPOS trial”) in the first half of 2024
  • Report initial data from the ongoing Phase 2 open-label biomarker trial of KER-012 in patients with chronic heart failure with preserved injection and in such patients with reduced ejection fraction in the second half of 2024

Headwinds

  • Limited operating history and historical losses
  • Ability to raise additional funding to complete the development and any commercialization of its product candidates
  • Dependence on the success of its product candidates, KER-050, KER-012 and KER-065
  • Potential delays in initiating, enrolling or completing any clinical trials
  • Competition from third parties that are developing products for similar uses

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

+0.4%

Avg return

Earnings day

+0.1%

Avg return

5 days after

+5.0%

Avg return

30 days after

42%

10 / 24 earnings

Positive

+34.0%

Q3 2021

Best reaction

-15.0%

Q4 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-8.5%-17.4%-15.4%
Q4 2025-15.0%-15.9%-12.9%
Q3 2025+3.4%+8.0%+38.6%
Q1 2025+0.7%+0.1%-3.3%
Q4 2024+0.6%+5.9%-1.4%
Q3 2024+7.3%+8.9%+11.9%
Q2 2024-8.9%-8.0%+7.7%
Q1 2024-1.8%-8.0%-17.0%
Q4 2023-3.6%-1.4%-5.4%
Q3 2023-0.3%-7.4%+4.8%
Q2 2023-10.3%-12.9%-12.9%
Q1 2023-2.6%-2.3%+8.6%
Q4 2022-6.4%-3.6%-23.4%
Q3 2022-2.0%-9.2%+3.2%
Q2 2022+14.7%+13.5%+10.6%
Q1 2022-12.5%-15.5%-36.5%
Q4 2021+8.7%-3.5%+29.9%
Q3 2021+34.0%+43.0%+30.3%
Q2 2021+5.5%+2.6%-3.7%
Q1 2021-2.4%-6.9%-13.5%
Q4 2020+4.4%+6.6%+14.0%
Q3 2020-0.9%+8.1%+41.4%
Q2 2020+7.1%+12.8%+23.6%
Q1 2020-2.0%+4.0%+41.0%
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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