NASDAQ$KLRS

Kalaris Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Reported full-year financial results and provided 2022 outlook.

AlloVir reported its full-year 2021 financial results, highlighting advancements in its clinical development programs, including three Phase 3 registrational studies for posoleucel. The company also reported a strong cash position with $248.1 million at year-end.

  • Three ongoing Phase 3 registrational studies of posoleucel are expected in 2022, targeting treatment and prevention indications.
  • Enrollment expanded in Phase 2 proof-of-concept study of posoleucel for BK viremia in kidney transplant recipients.
  • Two additional virus-specific T cell therapies are advancing: ALVR106 for respiratory viral infections and ALVR107 for hepatitis B cure.
  • Cash and cash equivalents totaled $248.1 million at year-end 2021.

Headline financials

EPS (adj)

-$0.92

Previous: -$1.27+27.6%
Capital Expenditures

-$370K

No prior period
Free Cash Flow

-$27.7M

No prior period
Net Income

-$172M

Previous: -$69.8M-146.4%
Operating Income

-$55.8M

Previous: -$71.3M+21.8%
Cash & Equivalents

$248M

Previous: $356M-30.4%
Total Assets

$287M

Previous: $371M-22.7%
Stock-Based Comp

$15.9M

No prior period

Revenue & EPS history

Allovir · Revenue · Quarterly

$0

Q3 2025

Forward guidance

AlloVir anticipates key milestones in 2022, including the advancement of posoleucel through Phase 3 trials and the continued development of its VST therapies.

Tailwinds

  • Global enrollment is ongoing in registrational studies of posoleucel for the treatment of virus-associated HC.
  • Global enrollment is ongoing in registrational studies of posoleucel for the treatment of AdV infections.
  • A Phase 3 registrational trial for multi-virus prevention is expected to initiate in the first half of this year.
  • Initial data from the ongoing posoleucel POC study for BKV treatment in KT recipients expected in the first half of 2022.
  • Preclinical and IND-enabling studies of ALVR107 to treat and cure hepatitis B will be completed in 2022.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+0.5%

Avg return

Earnings day

+0.4%

Avg return

5 days after

+5.9%

Avg return

30 days after

50%

11 / 22 earnings

Positive

+33.6%

Q2 2022

Best reaction

-23.8%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q3 2025-1.8%+6.9%+75.0%
Q2 2025-10.9%+0.4%+56.2%
Q2 2024-3.3%-5.7%+75.0%
Q1 2025-6.1%-2.8%+5.6%
Q4 2025-3.4%+4.2%-21.2%
Q3 2024-23.8%-23.0%-37.8%
Q1 2024-1.7%-1.4%+0.5%
Q4 2023+0.7%+2.5%+5.5%
Q3 2023+9.1%+9.1%+27.9%
Q2 2023+3.0%+0.3%+6.6%
Q1 2023+14.2%+13.0%+2.6%
Q4 2022-6.1%+5.5%-30.9%
Q3 2022+0.9%+9.1%+10.5%
Q2 2022+33.6%+37.7%+31.7%
Q1 2022+0.4%-23.8%-25.3%
Q4 2021+2.3%+3.6%-14.1%
Q3 2021-2.3%-3.0%-28.9%
Q2 2021+6.1%+0.6%+0.0%
Q1 2021+9.7%+5.0%+6.0%
Q4 2020+0.5%-2.5%-29.4%
Q3 2020-0.5%-6.3%+24.2%
Q2 2020-9.7%-20.6%-9.5%
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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