NASDAQ$JBIO

Jade Biosciences Inc · Q4 2025 earnings

Q4 2025 earnings · · Before market open · Investor relations

Briefing

JBIO reported Q4 2025, net loss of $31.9M.

For Q4 2025, JBIO reported a net loss of $31.9M. Management discusses segment performance, capital allocation, and macro risks in the quarterly filing.

  • Net loss $31.9M.
  • JBIO MD&A covers liquidity, credit, and operating priorities.
  • JBIO MD&A covers liquidity, credit, and operating priorities.

Headline financials

Total Revenue

$0.00

No prior period
EPS (adj)

-$0.45

No prior period
R&D Expenses

$28.5M

No prior period
G&A Expenses

$6.4M

No prior period
Net Income

-$31.9M

Previous: -$11.3M-182.0%
Operating Income

-$31.9M

No prior period

Revenue & EPS history

Aerovate · Revenue · Quarterly

$0

Q4 2025

Forward guidance

The quarterly filing discusses operating priorities, capital returns, and sector risks; numeric multi-quarter bridges vary by issuer.

Tailwinds

  • MD&A highlights liquidity, capital, and core business trends.
  • Segment or product commentary supports the earnings narrative.

Headwinds

  • Macro, rates, or input costs may pressure near-term margins.
  • One-time items can affect year-over-year comparability.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-1.6%

Avg return

Earnings day

-2.1%

Avg return

5 days after

+2.6%

Avg return

30 days after

56%

10 / 18 earnings

Positive

+24.6%

Q3 2023

Best reaction

-35.0%

Q3 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+1.2%+1.0%+11.6%
Q2 2025+0.1%-0.5%+4.9%
Q1 2025+1.8%-0.3%-4.8%
Q4 2024+0.4%+0.4%-85.8%
Q3 2024+0.0%-3.8%-2.7%
Q1 2024-2.8%+3.7%+16.1%
Q4 2023-0.5%+14.7%-17.8%
Q3 2023+24.6%+27.6%+68.5%
Q2 2023-3.5%-6.0%-10.8%
Q1 2023-7.6%-12.2%-19.8%
Q4 2022+0.7%+1.7%+9.4%
Q3 2022+0.6%-7.1%+32.9%
Q2 2022-13.7%-17.3%-26.4%
Q1 2022-6.3%+0.7%-5.9%
Q4 2021+8.0%-4.8%-24.9%
Q3 2021-35.0%-33.8%-42.7%
Q1 2021+1.8%-1.0%+72.5%
Q2 2021+1.8%-1.0%+72.5%
Q4 2020
Q3 2020
Q2 2020
Q1 2020

Discussion

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