NASDAQ$IRD

Opus Genetics Inc · Q1 2021 earnings

Q1 2021 earnings · · Investor relations

Briefing

Ocuphire reported positive data in a Phase 3 trial for Nyxol eye drops and advanced towards NDA submission.

Ocuphire Pharma announced positive top-line results from the pivotal MIRA-2 Phase 3 trial for Nyxol eye drops in reversal of mydriasis. The company also initiated multiple Phase 2 and 3 clinical trials and is progressing with its second product candidate, APX3330, in Diabetic Retinopathy.

  • Reported positive top-line results from the pivotal MIRA-2 Phase 3 trial for Nyxol eye drops in reversal of mydriasis.
  • Initiated ZETA-1 Phase 2 trial for APX3330 in Diabetic Retinopathy and Diabetic Macular Edema.
  • Initiated Phase 2 VEGA-1 trial evaluating Nyxol and low-dose pilocarpine in Presbyopia.
  • Presented positive pre-clinical data supporting APX3330's efficacy at the ARVO virtual Annual Meeting.

Headline financials

Total Revenue

$0.00

Previous: $1.15M-100.0%
EPS (adj)

-$0.47

Previous: -$0.82+42.9%
G&A Expenses

$1.7M

Previous: $391K+335.8%
Net Income

-$39M

Previous: -$587K-6546.6%
Operating Income

-$5.2M

Previous: -$563K-824.0%
Cash & Equivalents

$10.6M

Previous: $1.25M+745.7%
Total Assets

$12.1M

Previous: $11.6M+5.0%
Stock-Based Comp

$494K

Previous: $61K+709.8%

Revenue & EPS history

Ocuphire · Revenue · Quarterly

$0

Q1 2021-100%vs Q1 2020
Beat estimate in 1 of 2 quarters(50%)
ActualEstimate

Revenue by segment

Ocuphire · $100K total across 1 segment · Q2 2021

  • Collaboration Revenue
    $100K

Forward guidance

Ocuphire anticipates several milestones including top-line data readouts for Presbyopia and Night Vision Disturbances trials, presentation of Phase 3 MIRA-2 results, initiation of a second Phase 3 MIRA-3 trial, and completion of enrollment in the Phase 2 ZETA-1 trial.

Tailwinds

  • Top-line data expected end of Q2 2021 for Phase 2 VEGA-1 trial in Presbyopia
  • Presenting Phase 3 MIRA-2 results at the ASCRS conference in July
  • Top-line data expected end of Q3 2021 for Phase 3 LYNX-1 trial in Night Vision Disturbances
  • Planning to initiate second Phase 3 MIRA-3 trial in 2H 2021 for Reversal of Mydriasis
  • Completion of enrollment in Phase 2 ZETA-1 trial expected early 2022 for Diabetic Retinopathy and Diabetic Macular Edema

Headwinds

  • Success and timing of clinical trials are subject to regulatory submissions.
  • Regulatory requirements or developments could impact trial progress.
  • Changes to clinical trial designs and regulatory pathways may occur.
  • The company may face challenges in obtaining sufficient additional capital.
  • Legislative, regulatory, political, and economic developments could affect outcomes.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2021

Historical avgQ1 2021

-3.6%

Avg return

Earnings day

-3.8%

Avg return

5 days after

-3.7%

Avg return

30 days after

42%

14 / 33 earnings

Positive

+16.7%

Q1 2017

Best reaction

-47.3%

Q2 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.2%-6.1%-23.7%
Q4 2025+1.7%+5.5%+15.3%
Q3 2025-3.1%-11.7%+19.8%
Q2 2025+7.4%+0.9%+25.5%
Q1 2025+7.5%+4.2%+2.1%
Q3 2024-7.7%-9.4%-5.1%
Q2 2024-24.7%-19.9%-24.1%
Q1 2024-14.3%-11.7%-13.8%
Q4 2023-12.2%-13.9%-19.7%
Q3 2023+13.4%+3.5%-4.9%
Q2 2023+0.5%+0.7%-3.1%
Q1 2023-18.9%-28.0%-36.0%
Q4 2022+4.2%+44.2%+42.5%
Q3 2022-2.8%+13.1%+52.3%
Q2 2022-9.7%-6.1%-14.3%
Q1 2022+8.5%+6.5%+5.5%
Q4 2021+11.1%-9.9%-35.9%
Q3 2021-0.3%-10.9%-5.6%
Q2 2021-8.5%-14.7%-0.6%
Q1 2021-7.8%-5.9%+17.4%
Q4 2020-12.7%-7.8%-34.7%
Q3 2020+1.4%-10.8%-22.4%
Q2 2020-1.6%+1.2%-25.9%
Q1 2020-16.4%-2.7%+3.8%
Q3 2019-5.9%-9.3%-11.2%
Q2 2019-47.3%-49.3%-54.8%
Q1 2019-10.4%-11.0%-10.3%
Q2 2018+2.7%+5.4%+17.0%
Q4 2018-2.9%-3.5%-4.7%
Q3 2017+4.9%+6.5%+15.7%
Q2 2017+5.9%-1.6%+26.5%
Q1 2017+16.7%+29.2%-10.4%
Q2 2016+0.0%-3.7%-3.7%
Q1 2014
Q3 2013
Q2 2013
Q2 2012
Q1 2012
Q3 2011
Q2 2011

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