NASDAQ$IMNM

Immunome Inc · Q2 2025 earnings

Q2 2025 earnings · · After market close · Investor relations

Briefing

Immunome Inc reported financial results for the second quarter ended June 30, 2025, with higher collaboration revenue and increased operating expenses.

The company recognized $4.0 million in collaboration revenue during Q2 2025, up from the prior year period. Operating expenses rose, leading to a net loss of $43.4 million and EPS of $(0.50). The company maintained a strong liquidity position with $143.9 million in cash and cash equivalents.

  • Collaboration revenue increased to $4.0 million for the three months ended June 30, 2025.
  • R&D expenses were $40.5 million and G&A expenses were $10.0 million.
  • Net loss totaled $43.4 million with basic and diluted EPS of $(0.50).
  • Cash and cash equivalents stood at $143.9 million and total assets at $296.3 million at period end.

Headline financials

Total Revenue

$4.02M

Previous: $2.36M+69.8%
EPS (adj)

-$0.50

Previous: -$0.60+16.7%
In-process R&D Expenses

$0.00

No prior period
Interest Income

$3.08M

No prior period
Research and Development Expenses

$40.5M

No prior period
General and Administrative Expenses

$10M

No prior period
Weighted Average Shares Outstanding

87.0M

No prior period
Capital Expenditures

-$4.57M

Previous: -$4.51M-1.4%
Net Income

-$43.4M

Previous: -$36.1M-20.1%
Operating Income

-$46.5M

Previous: -$40M-16.2%
Cash & Equivalents

$144M

No prior period
Total Assets

$296M

No prior period

Revenue & EPS history

Immunome · Revenue · Quarterly

$4.02M

Q2 2025+69.8%vs Q2 2024
Beat estimate in 3 of 10 quarters(30%)
ActualEstimate

Revenue by segment

Immunome · $4.02M total across 1 segment · Q2 2025

  • Collaboration Revenue
    $4.02M

Forward guidance

The company plans to report topline data from the Phase 3 RINGSIDE trial of varegacestat in the second half of 2025 and initiate additional Phase 1 trials.

Tailwinds

  • Robust cash position to fund ongoing clinical development.
  • Multiple pipeline assets advancing with recent IND clearances.

Headwinds

  • Continued operating losses expected as R&D investment grows.
  • No product revenue anticipated until regulatory approvals are obtained.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 18 quarterly earnings reports

Historical avg

+0.8%

Avg return

Earnings day

-2.4%

Avg return

5 days after

+0.6%

Avg return

30 days after

32%

7 / 22 earnings

Positive

+24.1%

Q4 2021

Best reaction

-10.8%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2026-1.3%-9.1%-20.0%
Q4 2025+4.7%-1.0%+1.4%
Q3 2025-5.0%+2.5%+12.3%
Q1 2025+1.1%-1.0%+15.0%
Q4 2024-4.0%-18.9%-7.7%
Q3 2024-10.8%-24.5%+0.7%
Q2 2024+4.7%+4.7%+11.9%
Q1 2024-1.3%-6.2%-3.2%
Q4 2023-2.3%-16.2%-46.2%
Q3 2023-8.1%-8.9%-12.2%
Q2 2023-1.9%-0.8%+3.9%
Q1 2023+2.3%+11.9%-6.2%
Q4 2022+20.8%+18.9%+2.3%
Q3 2022+0.0%-27.6%-8.5%
Q2 2022+19.3%+13.6%+24.7%
Q1 2022-2.6%+19.6%+46.5%
Q4 2021+24.1%+20.1%-26.3%
Q3 2021-1.0%-5.1%-9.3%
Q2 2021-3.2%-11.9%+51.2%
Q1 2021-10.7%-3.0%-2.9%
Q4 2020-1.0%-4.3%-8.3%
Q3 2020-5.5%-6.4%-6.1%
Q2 2020
Q1 2020
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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