NASDAQ$IMCR

Immunocore Holdings plc · Q4 2025 earnings

Q4 2025 earnings · · Before market open · Investor relations

Briefing

Immunocore reported Q4 2025 KIMMTRAK net sales of $104.5 million and full-year net sales of $400.0 million.

Immunocore generated Q4 2025 KIMMTRAK (tebentafusp) net sales of $104.5 million, bringing full-year 2025 product revenue to $400.0 million with 15 consecutive quarters of growth. Cash, cash equivalents, and marketable securities totaled $864.2 million at year-end. The company is advancing multiple Phase 3 melanoma trials (TEBE-AM, ATOM) while expecting moderating KIMMTRAK revenue growth rates as the base scales.

  • Q4 KIMMTRAK net sales $104.5M; full-year $400.0M.
  • 15th consecutive quarter of KIMMTRAK revenue growth.
  • Cash ~$864M supports clinical pipeline execution.
  • Phase 3 programs in uveal and cutaneous melanoma advancing.

Headline financials

Total Revenue

$105M

Previous: $84.1M+24.3%
EPS (adj)

-$0.60

Previous: -$0.47-27.7%
KIMMTRAK Net Sales

$104M

Previous: $84.1M+24.3%
R&D Expenses

$78.8M

Previous: $60.9M+29.5%
SG&A Expenses

$42.6M

Previous: $42.3M+0.8%
Cash & Marketable Securities

$864M

No prior period
Net Income

-$30.1M

Previous: -$23.8M-26.5%
Operating Income

-$19.7M

Previous: -$19.5M-1.2%
Cash & Equivalents

$864M

No prior period

Revenue & EPS history

Immunocore · Revenue · Quarterly

$105M

Q4 2025+24.3%vs Q4 2024
Beat estimate in 8 of 15 quarters(53%)
ActualEstimate

Forward guidance

Management expects moderating KIMMTRAK growth in 2026 while prioritizing Phase 3 readouts; detailed revenue guidance is provided on the company's outlook slides.

Tailwinds

  • Commercial traction in first-in-class TCR bispecific for uveal melanoma.
  • Strong liquidity runway for oncology pipeline.
  • Diverse clinical portfolio beyond KIMMTRAK.

Headwinds

  • Growth rate normalization as KIMMTRAK matures.
  • Clinical trial execution and regulatory risks on label expansions.
  • Competitive IO landscape in melanoma.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-0.3%

Avg return

Earnings day

+0.9%

Avg return

5 days after

-1.2%

Avg return

30 days after

48%

10 / 21 earnings

Positive

+8.3%

Q3 2023

Best reaction

-11.0%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+6.6%+0.0%-2.1%
Q4 2025-4.8%-3.0%-12.6%
Q3 2025-3.2%+9.7%+21.5%
Q1 2025+6.3%+5.3%+32.8%
Q4 2024+5.3%-1.1%+1.3%
Q3 2024+4.0%+5.0%-4.5%
Q2 2024+0.8%+1.7%-9.5%
Q1 2024-1.9%-6.6%-31.7%
Q4 2023-4.6%-7.2%-7.7%
Q3 2023+8.3%+4.6%+15.8%
Q2 2023-3.3%-5.9%-12.7%
Q1 2023-1.5%+3.2%-4.6%
Q4 2022-4.9%-5.1%-9.9%
Q3 2022+2.9%+13.7%+9.3%
Q2 2022+1.6%+5.8%-13.5%
Q1 2022-11.0%+2.7%+1.4%
Q4 2021-0.7%+7.5%+37.7%
Q3 2021+0.4%-0.2%-21.3%
Q2 2021-4.9%-9.5%-1.4%
Q1 2021-1.5%-9.4%-5.3%
Q4 2020+0.1%+6.8%-7.1%
Q3 2020
Q2 2020
Q1 2020
Q4 2019

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