NASDAQ$ILMN

Illumina · Q1 2025 earnings

Q1 2025 earnings · · After market close · Investor relations

Briefing

Illumina reported Q1 2025 revenue of $1.04B with net income of $131M and diluted EPS of $0.82.

Revenue was $1.04 billion as sequencing consumables and instruments recovered from prior-year weakness. Net income was $131 million versus a loss a year ago; diluted EPS was $0.82. Clinical and research demand and China dynamics remain focal.

  • Q1 revenue $1.04B.
  • Net income $131M; diluted EPS $0.82.
  • Consumables and instrument placements improved YoY.
  • Competition and China policy affect outlook.

Headline financials

Total Revenue

$1.04B

Previous: $1.08B-3.3%
EPS (adj)

$0.82

Previous: -$0.79+203.8%
GAAP Gross Margin

65.6%

Previous: 65.7%-0.2%
Non-GAAP Gross Margin

67.4%

Previous: 67.1%+0.4%
GAAP Operating Margin

15.8%

Previous: 11.0%+43.6%
Non-GAAP Operating Margin

20.4%

Previous: 20.6%-1.0%
Capital Expenditures

-$32M

Previous: -$36M+11.1%
Net Income

$131M

Previous: -$126M+204.0%
Operating Income

$164M

Previous: -$111M+247.7%
Gross Profit

$683M

Previous: $667M+2.4%
R&D Expense

$255M

No prior period

Revenue & EPS history

Illumina · Revenue · Quarterly

$1.04B

Q1 2025-3.3%vs Q1 2024
Beat estimate in 12 of 15 quarters(80%)
ActualEstimate

Revenue by segment

Illumina · $147M total across 1 segment · Q1 2023

  • Service and Other Revenue
    $147M+5.0%

Forward guidance

Life-sciences outlook focuses on clinical milestones, R&D spend, and cash runway.

Tailwinds

  • Pipeline readouts and partnership potential.
  • Cash resources to fund development.

Headwinds

  • Trial and regulatory risk.
  • Operating losses until commercialization.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

-0.8%

Avg return

Earnings day

-1.7%

Avg return

5 days after

-0.7%

Avg return

30 days after

35%

22 / 63 earnings

Positive

+21.1%

Q3 2025

Best reaction

-19.1%

Q1 2022

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+2.3%+12.5%+28.5%
Q4 2025-10.4%-12.9%-6.7%
Q3 2025+21.1%+23.7%+32.8%
Q1 2025-4.9%-1.7%+3.9%
Q3 2024+3.5%+0.9%-4.8%
Q2 2024+4.9%+7.0%+12.4%
Q1 2024-5.4%-9.5%-16.4%
Q4 2023-3.6%-6.4%-5.3%
Q3 2023-11.1%-11.9%+2.0%
Q2 2023-0.6%-5.9%-14.9%
Q1 2023-7.9%-10.3%-15.5%
Q4 2022-4.9%-5.8%-2.9%
Q3 2022+6.3%+3.3%+3.7%
Q2 2022-8.3%-3.3%-7.5%
Q1 2022-19.1%-28.6%-24.3%
Q4 2021-10.0%-7.0%-17.4%
Q3 2021-2.7%-5.8%-17.2%
Q2 2021-1.5%+0.4%-7.5%
Q1 2021-3.6%-6.6%-2.8%
Q4 2020+12.2%+9.5%-10.0%
Q3 2020-5.5%-4.2%+2.4%
Q2 2020-11.2%-14.9%-14.6%
Q1 2020-3.6%-2.3%+14.4%
Q4 2019-5.8%+2.5%-6.7%
Q3 2019-7.0%-3.5%+1.0%
Q2 2019-0.3%-1.2%-6.4%
Q1 2019-0.2%-0.8%-0.7%
Q4 2018-5.3%-1.7%+8.7%
Q3 2018-8.7%-7.0%-2.3%
Q2 2018+7.7%+10.4%+16.4%
Q1 2018-6.0%-0.6%+10.2%
Q4 2017-3.8%-8.9%-7.1%
Q3 2017-3.2%-0.7%+1.8%
Q2 2017+13.8%+11.9%+17.6%
Q1 2017+2.4%+2.6%-3.6%
Q4 2016+1.4%+1.8%+5.3%
Q3 2016-0.4%-1.1%-6.2%
Q2 2016+7.7%+10.4%+12.5%
Q1 2016-0.7%
Q4 2015-6.0%
Q3 2015-5.0%
Q2 2015-9.4%
Q1 2015-1.6%
Q4 2014-1.9%
Q3 2014+8.9%
Q2 2014-2.6%
Q1 2014+8.8%
Q4 2013+4.6%
Q3 2013+10.6%
Q2 2013+9.1%
Q1 2013+11.3%
Q4 2012-3.6%
Q3 2012-1.1%
Q2 2012-2.7%
Q1 2012-1.9%
Q1 2011-3.5%
Q4 2011-4.1%
Q4 2008-4.1%
Q3 2010+2.2%
Q3 2011+2.2%
Q2 2010+3.6%
Q2 2011+3.6%
Q4 2010+3.6%

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