NASDAQ$HUMA

Humacyte Inc · Q1 2025 earnings

Q1 2025 earnings · · Before market open · Investor relations

Briefing

Humacyte announced its first quarter 2025 financial results and provided a business update, highlighting the commercial launch of Symvess and strategic cost reductions.

Humacyte reported total revenues of $517,000 for the first quarter of 2025, driven by initial commercial sales of Symvess and a research collaboration. The company achieved a net income of $39.1 million, a significant improvement from a net loss in the prior year, primarily due to a non-cash remeasurement of contingent earnout liability. They also completed a public offering raising $46.7 million in net proceeds and implemented cost reductions to extend their cash runway.

  • Humacyte commenced the commercial launch of Symvess in late February 2025, with initial sales to three Level 1 trauma centers.
  • The company reported total revenues of $517,000 for Q1 2025, including $147,000 from Symvess sales and $370,000 from a research collaboration.
  • Net income for Q1 2025 was $39.1 million, a substantial increase from a net loss of $31.9 million in Q1 2024, largely due to a non-cash remeasurement of contingent earnout liability.
  • Humacyte completed a public offering in March 2025, raising $46.7 million in net proceeds, and implemented cost reduction actions expected to save over $50 million in 2025 and 2026.

Headline financials

Total Revenue

$517K

Previous: $0.00
EPS (adj)

$0.28

Previous: -$0.29+196.6%
Hospitals with VAC approval

5

No prior period
Hospitals in VAC review

45

No prior period
V012 Trial Enrollment

84

No prior period
Net proceeds from equity raise

$46.7M

No prior period
Capital Expenditures

-$228K

Previous: $391K-158.3%
Net Income

$39.1M

Previous: -$31.9M+222.7%
Operating Income

-$23.2M

Previous: -$26.6M+12.8%

Revenue & EPS history

Humacyte · Revenue · Quarterly

$517K

Q1 2025
Beat estimate in 2 of 15 quarters(13%)
ActualEstimate

Forward guidance

Humacyte plans to aggressively expand its commercial launch of Symvess, continue developing its bioengineering pipeline, and pursue regulatory filings for additional indications, while maintaining cost discipline.

Tailwinds

  • Aggressively expanding commercial launch of Symvess.
  • Creating value from the bioengineering pipeline with upcoming major value drivers.
  • Anticipated publications of additional clinical results in trauma and dialysis access.
  • Planned filing of an Investigational New Drug (IND) application for small-diameter ATEV in coronary artery bypass grafting (CABG) later this year.
  • On track for filing a supplemental Biologics License Application (BLA) for ATEV in dialysis in 2026.

Headwinds

  • Current volatile economic environment may impact traction with hospitals.
  • Unfounded negative press regarding Symvess and Humacyte.
  • One-time cash expenditure of approximately $0.8 million for severance and employee termination benefits expected in Q2 2025.
  • The company's ability to achieve objectives and plans is subject to significant risks and uncertainties.
  • No specific revenue or profit guidance was provided for future periods.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q1 2025

Historical avgQ1 2025

+5.1%

Avg return

Earnings day

+2.0%

Avg return

5 days after

+3.5%

Avg return

30 days after

62%

13 / 21 earnings

Positive

+37.0%

Q2 2023

Best reaction

-30.1%

Q2 2025

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+22.9%-1.5%+15.2%
Q4 2025-15.1%-25.1%-33.0%
Q3 2025-3.2%-11.7%+2.3%
Q2 2025-30.1%-24.2%-40.3%
Q1 2025+19.5%+23.8%+25.4%
Q4 2024-2.5%-27.4%-28.4%
Q3 2024+4.9%+1.5%-8.2%
Q1 2024+21.2%+43.1%+60.8%
Q4 2023-12.8%-13.9%+2.8%
Q3 2023+7.3%+9.1%+27.9%
Q2 2023+37.0%+8.9%+19.0%
Q1 2023-6.1%-2.5%+1.1%
Q4 2022+4.9%-1.3%+7.1%
Q3 2022+2.2%-5.4%-4.5%
Q2 2022+8.6%+9.1%+2.5%
Q1 2022-9.5%-12.7%-18.8%
Q4 2021+14.1%+12.2%+16.5%
Q2 2021+14.1%+12.2%+16.5%
Q3 2021+9.0%+18.4%+4.0%
Q1 2021+0.0%+0.0%+4.9%
Q4 2020+21.2%+28.4%+1.5%
Q3 2020

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