NASDAQ$GYRE

Gyre Therapeutics Inc · Q4 2023 earnings

Q4 2023 earnings · · Investor relations

Briefing

Gyre Therapeutics reported financial results for the full year ended December 31, 2023, and provided a business update, including updates on clinical trials and commercial activities.

Gyre Therapeutics reported full year 2023 financial results, highlighting a transformational year with the acquisition of F351 and strong ETUARY sales. The company is progressing with clinical trials for F351 and F573, and expects to report data from the Phase 3 trial evaluating F351 for CHB-associated liver fibrosis in the PRC by early 2025.

  • Gyre acquired an indirect controlling interest in Beijing Continent Pharmaceuticals Co., Ltd.
  • Cash and cash equivalents totaled $33.5 million as of December 31, 2023.
  • ETUARY sales increased by 13% from 2022, generating $112.1 million in 2023.
  • Phase 3 clinical trial data readout for F351 in the PRC is expected by early 2025.

Headline financials

Total Revenue

$27.1M

Previous: $102M-73.5%
EPS (adj)

-$1.31

Previous: -$1.28-2.3%
Capital Expenditures

$2.32M

Previous: $4.99M-53.4%
Net Income

-$81.7M

Previous: -$40.5M-101.9%
Operating Income

-$63.2M

Previous: -$40.3M-57.0%
Gross Profit

$25.9M

Previous: $97.5M-73.4%
Stock-Based Comp

$6.88M

Previous: $257K+2578.6%

Revenue & EPS history

Gyre Therapeutics · Revenue · Quarterly

$27.1M

Q4 2023-73.5%vs Q4 2022
Beat estimate in 1 of 3 quarters(33%)
ActualEstimate

Revenue by segment

Gyre Therapeutics · $2.3M total across 1 segment · Q3 2021

  • License & Collaboration
    $2.3M

Forward guidance

Gyre expects 2024 sales of ETUARY to grow due to ETUARY’s prominent market position and anticipated sustained increases in the prevalence of IPF.

Tailwinds

  • Gyre's sales and marketing team included 391 employees with an average of nine years of experience.
  • The sales and marketing team covered 35,512 hospitals and pharmacies across 30 provinces, autonomous regions and municipalities across the PRC.
  • Gyre expects 2024 sales of ETUARY to grow due to ETUARY’s prominent market position.
  • Gyre anticipates sustained increases in the prevalence of IPF.
  • Gyre Pharmaceuticals maintained its market-leading position in the PRC IPF market, providing funding for our clinical development plans.

Headwinds

  • Data readout from Phase 3 clinical trial in the People's Republic of China (“PRC”) evaluating F351 for the treatment of CHB-associated liver fibrosis expected by early 2025
  • U.S. Phase 2a clinical trial evaluating F351 for the treatment of NASH-associated liver fibrosis planned for 2025
  • Operating Loss: For the full year ended December 31, 2023, loss from operations was $67.2 million, compared to $9.2 million in operating income for the same period in 2022.
  • Net Loss: For the full year ended December 31, 2023, net loss was $85.5 million, compared to $4.3 million in net income for the same period in 2022.
  • The company is still loss making.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2023

Historical avgQ4 2023

-0.7%

Avg return

Earnings day

+0.3%

Avg return

5 days after

+8.5%

Avg return

30 days after

49%

23 / 47 earnings

Positive

+11.6%

Q3 2018

Best reaction

-43.2%

Q3 2021

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+5.8%+2.8%-11.2%
Q4 2025+2.0%-10.2%-5.4%
Q3 2025-1.6%+13.6%+8.7%
Q1 2025+0.5%+9.6%-11.3%
Q3 2024-13.6%-21.2%-39.8%
Q2 2024-6.5%+2.1%+28.7%
Q1 2024-5.5%+0.5%-29.3%
Q4 2023+8.3%+8.0%+0.9%
Q3 2023+0.0%-15.3%+144.2%
Q2 2023+8.8%+58.8%+50.0%
Q1 2023+5.0%+5.0%+5.0%
Q4 2022+5.0%+5.0%+5.0%
Q3 2022-1.8%+0.0%-12.5%
Q2 2022-1.6%+3.6%+2.1%
Q1 2022-24.5%-26.5%+173.5%
Q4 2021+0.0%-3.0%-27.3%
Q3 2021-43.2%-51.0%-62.9%
Q2 2021+7.4%+3.7%+10.3%
Q1 2021-2.4%-5.4%-9.5%
Q3 2020+4.5%+7.4%+11.3%
Q2 2020-0.6%-2.0%-13.5%
Q1 2020+7.2%-2.7%+21.9%
Q3 2019-3.1%-6.1%-8.7%
Q2 2019+6.7%-3.2%-22.1%
Q1 2019-5.3%+2.7%-9.2%
Q3 2018+11.6%+24.7%+20.0%
Q2 2018+6.6%+6.6%+11.9%
Q2 2015
Q1 2015
Q4 2014+2.3%
Q3 2014+1.2%
Q2 2014-0.4%
Q1 2014+3.7%
Q4 2013-0.8%
Q3 2013-5.4%
Q2 2013-3.6%
Q1 2013+0.5%
Q4 2012-0.5%
Q3 2012+0.7%
Q2 2012-0.9%
Q1 2011-2.7%
Q1 2012+0.4%
Q4 2011+0.1%
Q4 2009+0.1%
Q3 2010+3.9%
Q3 2011+3.9%
Q2 2010-1.4%
Q2 2011-1.4%
Q4 2010-1.4%

Discussion

Share your read of this quarter. Sign-in carries your eToro identity.

Join the conversation

Sign in with eToro to post your read of this quarter and vote on others'.

Sign in with eToro