NASDAQ$GOSS

Gossamer Bio Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Gossamer Bio reported Q4 2025 collaboration revenue of $13.8M and a net loss of $47.2M ($0.21 per share).

Q4 collaboration revenue was $13.8 million versus $9.4 million a year ago. Net loss was $47.2 million, or $0.21 per share, with cash and marketable securities of $136.9 million at year-end.

  • PROSERA Phase 3 narrowly missed prespecified alpha on 6MWD but showed activity in higher-risk PAH patients.
  • SERANATA enrollment paused pending regulatory review of PROSERA implications.
  • Workforce reduction aligns resources with FDA engagement and strategic planning.
  • Plans Type C meeting potentially June 2026.
  • FY25 net loss $170.4M, or $0.75 per share.

Headline financials

Total Revenue

$13.8M

Previous: $9.38M+47.1%
EPS (adj)

-$0.21

Previous: -$0.15-40.0%
Net Income

-$47.2M

Previous: -$33M-42.9%

Revenue & EPS history

Gossamer Bio · Revenue · Quarterly

$13.8M

Q4 2025+47.1%vs Q4 2024
Beat estimate in 6 of 7 quarters(86%)
ActualEstimate

Revenue by segment

Gossamer Bio · $17M total across 1 segment · Q1 2026

  • Collaborators
    $17M

Forward guidance

Type C FDA meeting planned on PROSERA; SERANATA paused while evaluating regulatory paths.

Tailwinds

  • Subgroup signals support continued dialogue with FDA and Chiesi.
  • Cash runway into Q1 2027 on current resources.

Headwinds

  • Primary endpoint did not meet prespecified statistical threshold.
  • Financing and strategic options remain critical.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-0.6%

Avg return

Earnings day

-1.3%

Avg return

5 days after

-1.1%

Avg return

30 days after

43%

13 / 30 earnings

Positive

+15.2%

Q4 2022

Best reaction

-15.6%

Q1 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.2%-34.9%-50.9%
Q4 2025-10.8%-21.0%-5.5%
Q3 2025+2.2%+16.9%+44.2%
Q2 2025-8.5%-18.9%+15.7%
Q1 2025+1.0%+9.5%+18.1%
Q4 2024+0.0%+6.0%-38.4%
Q3 2024-0.9%-4.4%-15.1%
Q2 2024+4.3%+7.5%+12.5%
Q1 2024-3.2%-5.0%-23.2%
Q4 2023+4.1%-4.8%-26.2%
Q3 2023-12.0%+4.7%+73.1%
Q2 2023-7.0%-9.3%-24.7%
Q1 2023+3.7%-11.8%-7.4%
Q4 2022+15.2%+5.7%-0.5%
Q3 2022-0.8%-4.2%-14.9%
Q2 2022+4.6%+6.5%+13.7%
Q1 2022+12.5%+34.2%+9.5%
Q4 2021+3.7%+1.0%-2.8%
Q3 2021-1.4%-9.1%-16.6%
Q2 2021-0.8%+9.5%+18.9%
Q1 2021-0.7%-0.7%+1.7%
Q4 2020-9.4%-5.5%-11.6%
Q3 2020-0.9%-1.3%+4.2%
Q2 2020+5.1%+2.4%-1.1%
Q1 2020-15.6%-11.5%-27.8%
Q4 2019+5.5%+5.7%+40.0%
Q3 2019-4.3%-1.2%+12.4%
Q2 2019-2.5%+3.2%+2.6%
Q1 2019+1.3%+3.7%-3.9%
Q4 2018-4.9%-10.8%-30.1%
Q3 2018
Q2 2018
Q1 2018
Q4 2017
Q3 2017
Q2 2017
Q1 2017

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