NASDAQ$EYPT

EyePoint Inc · Q2 2025 earnings

Q2 2025 earnings · · Before market open · Investor relations

Briefing

EyePoint reported a net loss of $59.4 million for the second quarter of 2025 driven by increased R&D spending on Phase 3 trials.

Total revenue for the quarter was $5.3 million, primarily from license and collaboration agreements. Operating expenses rose to $67.6 million, led by $55.5 million in R&D costs for DURAVYU Phase 3 trials. The company ended the quarter with $255.7 million in cash, cash equivalents, and marketable securities.

  • Q2 2025 revenue totaled $5.3 million, down 44% year-over-year due to lower product sales and royalties.
  • R&D expenses increased 86% to $55.5 million, reflecting ongoing LUGANO and LUCIA Phase 3 trials.
  • Net loss widened to $59.4 million ($0.85 per share) from $30.8 million in Q2 2024.
  • Cash, cash equivalents, and marketable securities stood at $255.7 million, sufficient to fund operations into 2027.

Headline financials

Total Revenue

$5.33M

Previous: $9.48M-43.7%
EPS (adj)

-$0.85

Previous: -$0.58-46.6%
Research and development

$55.5M

Previous: $12.1M+358.7%
Sales and marketing

$35K

No prior period
General and administrative

$11.9M

No prior period
Capital Expenditures

-$1.5M

Previous: -$2.09M+28.6%
Net Income

-$59.4M

Previous: -$30.8M-92.8%
Operating Income

-$62.2M

Previous: -$34.5M-80.1%
Cash & Equivalents

$71.1M

No prior period

Revenue & EPS history

EyePoint Pharmaceuticals · Revenue · Quarterly

$5.33M

Q2 2025-43.7%vs Q2 2024
Beat estimate in 10 of 16 quarters(63%)
ActualEstimate

Revenue by segment

EyePoint Pharmaceuticals · $15.2M total across 2 segments · Q3 2023

  • License and Royalties
    $14.4M+27565.4%
  • Product sales, net
    $816K-91.6%

Forward guidance

Cash position of $255.7 million expected to fund operations into 2027 beyond topline data readout in 2026.

Tailwinds

  • Phase 3 LUGANO enrollment completed in May 2025
  • Phase 3 LUCIA enrollment completed in July 2025
  • Positive EOP2 FDA meeting for DME program

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports

Historical avg

-0.4%

Avg return

Earnings day

-1.2%

Avg return

5 days after

-3.7%

Avg return

30 days after

48%

28 / 58 earnings

Positive

+21.1%

Q3 2023

Best reaction

-37.2%

Q3 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q2 2025
Q1 2026+0.4%+1.9%-11.9%
Q4 2025-1.9%-14.5%-26.9%
Q3 2025-11.0%-8.4%+43.2%
Q1 2025-2.2%-6.4%+43.0%
Q4 2024+8.2%+16.6%-24.2%
Q3 2024-3.7%-8.0%-27.9%
Q2 2024+1.6%-7.3%-11.6%
Q1 2024+6.7%+2.9%-23.3%
Q4 2023-5.2%-11.4%-21.2%
Q3 2023+21.1%+26.7%+9.8%
Q2 2023-1.3%-2.6%-17.2%
Q1 2023+4.5%-0.3%-7.9%
Q4 2022+2.8%-0.9%-7.3%
Q3 2022-1.3%-3.5%-37.5%
Q2 2022+13.3%+14.2%-0.2%
Q1 2022-4.9%-19.5%-23.8%
Q4 2021+16.6%+34.3%+23.9%
Q3 2021+10.1%+26.1%+18.6%
Q2 2021+6.5%+8.3%+28.7%
Q1 2021-8.1%-14.8%-12.0%
Q4 2020-18.6%-12.4%-6.8%
Q3 2020-7.5%+10.0%+30.0%
Q2 2020-8.2%-6.8%-32.9%
Q1 2020-3.3%-2.2%-8.9%
Q4 2019-11.1%-27.1%-47.2%
Q3 2019-37.2%-41.6%-35.1%
Q2 2019+11.9%+3.2%+20.6%
Q4 2018-3.5%+2.2%+41.0%
Q3 2018+6.7%-15.9%-4.6%
Q2 2018-2.7%-5.5%+12.7%
Q1 2018-2.4%+9.5%+0.8%
Q4 2017+1.6%-5.5%-3.1%
Q3 2017+16.6%+17.8%+33.1%
Q2 2017+4.1%+5.3%+0.0%
Q1 2017+1.0%-2.0%-11.2%
Q4 2016+1.6%-4.1%-35.7%
Q3 2016+0.7%
Q2 2016-10.1%
Q1 2016-2.3%
Q4 2015-1.3%
Q3 2015-12.3%
Q2 2015+2.3%
Q1 2015+1.1%
Q4 2014-1.5%
Q3 2014+2.2%
Q2 2014+4.6%
Q1 2014-0.4%
Q4 2013+2.2%
Q3 2013+0.0%
Q3 2012+2.1%
Q4 2010-0.6%
Q4 2012+3.1%
Q1 2012+0.9%
Q4 2011-6.9%
Q3 2011-5.5%
Q1 2011+1.6%
Q3 2010-1.7%
Q1 2010-4.1%

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