NASDAQ$EWTX

Edgewise Therapeutics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Reported financial results for the fourth quarter and full year of 2021 and recent business highlights.

Edgewise Therapeutics reported positive topline results from the EDG-5506 Phase 1b clinical trial in adults with Becker muscular dystrophy (BMD). Phase 2 trials in BMD and Duchenne muscular dystrophy (DMD) are planned to start in 2022. Cash, cash equivalents and marketable securities were $281 million as of December 31, 2021.

  • Announced positive topline results from the EDG-5506 Phase 1b clinical trial in adults with Becker muscular dystrophy (BMD).
  • Phase 2 trials in BMD and Duchenne muscular dystrophy (DMD) planned to start in 2022.
  • Initiated treatment in the ARCH open label study evaluating EDG-5506 in adult males with BMD.
  • Cash, cash equivalents and marketable securities were $281 million as of December 31, 2021.

Headline financials

EPS (adj)

-$0.26

Previous: -$23.17+98.9%
R&D Expenses

$9.09M

No prior period
G&A Expenses

$3.73M

No prior period
Capital Expenditures

$79K

No prior period
Free Cash Flow

-$9.5M

Previous: -$4.64M-104.8%
Net Income

-$12.7M

Previous: -$6.34M-100.2%
Operating Income

-$12.8M

Previous: -$6.34M-102.1%
Cash & Equivalents

$281M

Previous: $105M+167.6%
Total Assets

$285M

Previous: $131M+117.5%
Stock-Based Comp

$1.87M

Previous: $190K+885.8%

Revenue & EPS history

Edgewise Therapeutics · Revenue · Quarterly

$0

Q3 2025

Forward guidance

The Company anticipates initiating Phase 2 trials in individuals with BMD in the first half of 2022 and DMD in the second half of 2022. The Company anticipates interim data from the ARCH trial in the first half of 2022.

Tailwinds

  • Initiating Phase 2 trials in individuals with BMD in the first half of 2022
  • Initiating Phase 2 trials in individuals with DMD in the second half of 2022
  • Advancing the EDG-002 program, focused on identifying cardiac muscle modulators
  • Advancing EDG-5440, a next generation myosin ATPase modulator designed to target skeletal muscle
  • Anticipates interim data from the ARCH trial in the first half of 2022

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

-0.2%

Avg return

Earnings day

+0.7%

Avg return

5 days after

-4.0%

Avg return

30 days after

40%

8 / 20 earnings

Positive

+16.0%

Q2 2022

Best reaction

-12.3%

Q1 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026-1.7%-4.3%+2.4%
Q3 2025-1.7%+23.7%+35.8%
Q2 2025-4.1%-0.9%+15.2%
Q1 2025+2.4%+1.0%+5.8%
Q4 2024-2.4%+7.0%-40.7%
Q3 2024-0.7%-3.9%-11.0%
Q1 2024-12.3%-16.5%-15.5%
Q4 2023-1.3%-3.7%-7.1%
Q3 2023-10.7%+5.5%+13.0%
Q2 2023+3.4%+12.5%-3.4%
Q1 2023-6.5%-5.5%-2.8%
Q4 2022-3.0%-2.8%-30.3%
Q3 2022+1.8%+2.1%-5.7%
Q2 2022+16.0%+6.8%+17.1%
Q1 2022+1.6%-0.8%-18.9%
Q4 2021+13.0%-2.5%-19.3%
Q3 2021-1.8%-3.4%-3.1%
Q2 2021-5.6%-10.6%-7.9%
Q1 2021+5.2%+4.7%-1.6%
Q4 2020+5.2%+4.7%-1.6%
Q3 2020
Q2 2020
Q1 2020

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