NASDAQ$ELVN

Enliven Therapeutics Inc · Q4 2025 earnings

Q4 2025 earnings · · After market close · Investor relations

Briefing

Enliven Therapeutics reported Q4 2025 financial results and clinical progress updates.

Enliven Therapeutics reported fourth-quarter and full-year 2025 financial results alongside pipeline updates for its precision oncology programs, including cash position and R&D spend.

  • Clinical-stage oncology biotech update.
  • Q4/FY2025 cash runway disclosed.
  • Precision medicine pipeline advancement.
  • Partnership and trial milestone focus.
  • Operating losses consistent with development stage.

Headline financials

Total Revenue

$0.00

Previous: $0.00
EPS (adj)

-$0.48

Previous: -$0.46-4.3%
R&D Expenses

$21.2M

Previous: $20.7M+2.5%
G&A Expenses

$13M

Previous: $6.17M+111.3%
Total Operating Expenses

$34.3M

Previous: $26.9M+27.5%
Other Income, Net

$4.62M

Previous: $3.72M+24.3%
Weighted Avg Shares

62.2M

Previous: 49.9M+24.8%
Net Income

-$29.7M

Previous: -$89M+66.7%
Operating Income

-$34.3M

Previous: -$26.9M-27.5%

Revenue & EPS history

Enliven Therapeutics · Revenue · Quarterly

$0

Q4 2025

Forward guidance

2026 milestones tied to clinical readouts and financing needs.

Tailwinds

  • Targeted oncology mechanisms.
  • Potential biomarker-selected populations.
  • Experienced management in precision oncology.

Headwinds

  • No product revenue yet.
  • Clinical and regulatory risk.
  • Capital markets dependence.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2025

Historical avgQ4 2025

-0.4%

Avg return

Earnings day

+2.4%

Avg return

5 days after

+7.4%

Avg return

30 days after

48%

11 / 23 earnings

Positive

+17.6%

Q2 2020

Best reaction

-22.5%

Q4 2020

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+4.3%+3.4%+35.1%
Q3 2025-0.3%+11.3%-16.9%
Q2 2025-0.8%-1.1%-0.1%
Q1 2025+0.4%+19.7%+29.3%
Q4 2024-3.5%-7.7%-14.6%
Q3 2024-8.3%-8.4%-14.8%
Q1 2024-2.0%-5.9%-10.1%
Q4 2023-2.4%+43.0%+71.8%
Q3 2023-9.3%-12.4%-4.5%
Q2 2023-2.0%-8.0%-7.1%
Q1 2023-2.4%-0.3%+8.8%
Q4 2022+2.1%+4.5%+2.6%
Q3 2022+0.4%-5.5%-1.3%
Q2 2022+2.5%-1.7%-3.4%
Q1 2022-6.1%-11.5%-12.2%
Q4 2021+11.1%+22.2%-27.8%
Q3 2021+0.8%-3.8%-20.2%
Q2 2021+0.3%-18.0%-14.5%
Q1 2021+12.8%+15.8%+27.3%
Q4 2020-22.5%-19.5%-31.7%
Q3 2020-3.4%+13.9%+57.0%
Q2 2020+17.6%+19.8%+8.1%
Q1 2020+1.1%+4.4%+108.5%
Q4 2019
Q3 2019
Q2 2019
Q1 2019

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