NASDAQ$DFTX

Definium Therapeutics Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

MindMed reported an increased net loss in Q4 2024 as research and development expenses surged due to Phase 3 trial advancements.

MindMed reported a Q4 2024 net loss of $34.74 million, widening from $23.86 million in Q4 2023, driven by higher R&D costs as the company advanced its MM120 ODT Phase 3 trials. Operating expenses increased to $32.46 million from $22.21 million in the prior year period. Cash and cash equivalents grew significantly to $273.74 million, extending the company’s cash runway into 2027. MindMed continues its focus on progressing clinical trials for its pipeline of innovative brain health treatments.

  • Q4 2024 net loss increased to $34.74 million from $23.86 million in Q4 2023.
  • Operating expenses rose to $32.46 million, driven by higher R&D costs.
  • Cash and cash equivalents reached $273.74 million, securing funding into 2027.
  • Phase 3 trials for MM120 ODT in Generalized Anxiety Disorder and Major Depressive Disorder are on track.

Headline financials

Total Revenue

$0.00

Previous: $4.84M-100.0%
EPS (adj)

-$0.41

Previous: -$0.59+30.5%
R&D expense

$21.8M

No prior period
G&A expense

$10.7M

No prior period
Capital Expenditures

$0.00

Previous: $0.00
Net Income

-$34.7M

Previous: -$95.7M+63.7%
Operating Income

-$32.5M

Previous: -$93.9M+65.4%
Gross Profit

$0.00

Previous: $4.05M-100.0%

Revenue & EPS history

MindMed · Revenue · Quarterly

$0

Q4 2024-100%vs Q4 2023
Beat estimate in 0 of 1 quarters(0%)
ActualEstimate

Forward guidance

MindMed expects continued investment in its clinical programs, with Phase 3 trials progressing for MM120 ODT in GAD and MDD. The company anticipates further R&D expenses but remains well-funded into 2027.

Tailwinds

  • Phase 3 trials for MM120 ODT in GAD and MDD are on schedule.
  • Cash runway secured into 2027, providing financial stability.
  • Breakthrough therapy designation received for MM120 in GAD from the FDA.
  • Expanded pipeline includes additional indications beyond anxiety and depression.
  • Strengthened leadership team with key strategic hires.

Headwinds

  • Continued net losses expected due to high R&D investments.
  • No reported revenue in Q4 2024, as the company remains pre-commercial.
  • Potential delays in trial enrollment could impact regulatory timelines.
  • Stock price volatility due to biotech sector uncertainties.
  • Regulatory risks remain, given the novel nature of psychedelic-based treatments.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+0.8%

Avg return

Earnings day

+2.9%

Avg return

5 days after

+3.0%

Avg return

30 days after

44%

14 / 32 earnings

Positive

+25.8%

Q3 2024

Best reaction

-25.0%

Q1 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2026+0.9%+2.7%+3.4%
Q3 2025+3.2%+7.1%+8.9%
Q2 2025-7.3%+8.8%-2.3%
Q1 2025+4.4%+6.5%+26.2%
Q4 2024+3.6%-0.7%-14.9%
Q3 2024+25.8%+21.3%+10.2%
Q1 2024-4.5%-11.5%-24.1%
Q4 2023+2.9%+12.2%+69.1%
Q3 2023+24.1%+13.3%+41.4%
Q2 2023-5.2%-5.4%-10.5%
Q1 2023-7.6%-10.8%-6.4%
Q4 2022-9.9%-8.1%-12.3%
Q3 2022+19.9%+18.7%+9.5%
Q2 2022+11.3%+4.3%-15.0%
Q1 2022-0.8%-1.2%-2.3%
Q4 2021+0.0%-9.3%-30.9%
Q4 2020-7.0%-7.7%-5.8%
Q3 2020+8.2%+13.3%+28.8%
Q2 2020+14.9%+5.7%-9.2%
Q1 2020+4.5%-5.2%+2.0%
Q3 2019-13.7%-13.7%+29.4%
Q2 2019+0.0%+33.3%+11.1%
Q1 2019-25.0%+38.3%-1.7%
Q4 2018-1.9%-3.7%+11.1%
Q3 2018-4.2%+4.2%-12.5%
Q2 2018-0.9%-6.0%-39.6%
Q1 2018-8.4%-9.8%-15.8%
Q4 2017-4.4%+0.0%+2.4%
Q3 2017+1.6%+9.6%-2.7%
Q2 2017-1.9%-7.5%-0.4%
Q1 2016+1.5%-6.4%-10.1%
Q4 2016+0.0%+0.0%+58.2%

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