NASDAQ$CYTK

Cytokinetics Inc · Q4 2021 earnings

Q4 2021 earnings · · Investor relations

Briefing

Cytokinetics reported a net loss and increased revenue due to license revenue from Ji Xing.

Cytokinetics reported a net loss of $30.6 million for Q4 2021, with revenues increasing to $55.6 million compared to $6.7 million in the same period of 2020, primarily driven by license revenue from Ji Xing. The company's cash balance reached $623.7 million at the end of the year, and they anticipate revenue between $20 to $25 million for 2022.

  • Net loss for Q4 2021 was $30.6 million, or $0.36 per share.
  • Revenues for Q4 2021 increased to $55.6 million, up from $6.7 million in Q4 2020.
  • Cash, cash equivalents, and investments totaled $623.7 million as of December 31, 2021.
  • The company anticipates revenue between $20 to $25 million for 2022.

Headline financials

Total Revenue

$55.6M

Previous: $6.72M+727.1%
EPS (adj)

-$0.36

Previous: -$0.62+41.9%
Capital Expenditures

$17.8M

Previous: $6.56M+170.8%
Free Cash Flow

-$62.5M

Previous: $45.6M-237.1%
Net Income

-$30.6M

Previous: -$43.9M+30.3%
Operating Income

-$21.7M

Previous: -$36.4M+40.4%
Gross Profit

$12.1M

Previous: -$22.5M+153.8%
Cash & Equivalents

$624M

Previous: $501M+24.5%
Total Assets

$841M

Previous: $534M+57.6%
Stock-Based Comp

$6.71M

Previous: $4.88M+37.6%

Revenue & EPS history

Cytokinetics · Revenue · Quarterly

$55.6M

Q4 2021+727.1%vs Q4 2020
Beat estimate in 10 of 16 quarters(63%)
ActualEstimate

Forward guidance

Cytokinetics provided financial guidance for 2022, anticipating revenue between $20 to $25 million, operating expenses in the range of $380 to $400 million, and net cash utilization of approximately $365 to $385 million.

Tailwinds

  • Revenue expected to be between $20 to $25 million.
  • Cash balance of $724 million, providing more than two years of runway.
  • Committed capital expected upon dosing of the first patient in SEQUOIA-HCM.
  • Focus on expanding the development program for aficamten.
  • Advancing the pipeline of early drug candidates.

Headwinds

  • Operating expenses expected to be in the range of $380 to $400 million.
  • Net cash utilization expected to be approximately $365 to $385 million.
  • Potential difficulties or delays in development and regulatory approvals.
  • Patient enrollment for clinical trials may be difficult or delayed.
  • The FDA or foreign regulatory agencies may delay or limit clinical trials.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 20 quarterly earnings reports · overlaid with Q4 2021

Historical avgQ4 2021

+0.4%

Avg return

Earnings day

+1.6%

Avg return

5 days after

+2.2%

Avg return

30 days after

49%

32 / 65 earnings

Positive

+21.4%

Q4 2014

Best reaction

-17.7%

Q2 2015

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+16.8%+16.5%+9.5%
Q4 2025-10.3%-12.4%-10.8%
Q3 2025+1.9%+12.4%+10.9%
Q1 2025-2.8%-5.4%-4.9%
Q4 2024-3.1%-7.5%-9.0%
Q3 2024+6.3%+11.6%-3.0%
Q2 2024+8.9%+9.5%+5.6%
Q1 2024-1.9%-11.3%-19.1%
Q4 2023-7.5%-6.4%-11.3%
Q3 2023+3.5%+2.1%-4.4%
Q2 2023+6.8%+2.8%+15.8%
Q1 2023+0.3%-1.3%-1.8%
Q4 2022-8.7%-9.8%-18.8%
Q3 2022-9.8%-8.6%-3.3%
Q2 2022+21.0%+22.5%+26.2%
Q1 2022+0.9%-12.6%+7.2%
Q4 2021+11.7%+14.7%+16.3%
Q3 2021+12.4%+18.2%+2.4%
Q2 2021+7.8%+8.2%+10.0%
Q1 2021+2.8%+0.8%-13.4%
Q4 2020-9.7%-6.4%+15.0%
Q3 2020+5.1%+0.8%+2.4%
Q2 2020-2.8%-4.7%+2.2%
Q1 2020-4.2%+27.8%+23.3%
Q4 2019+4.4%+1.1%-15.4%
Q3 2019-5.5%-6.5%-18.3%
Q2 2019+1.1%-2.0%+5.5%
Q1 2019+12.6%+16.7%+10.4%
Q4 2018-0.8%-2.7%+19.2%
Q3 2018+10.6%+5.7%+17.5%
Q2 2018-5.7%-7.0%-9.5%
Q1 2018+19.3%+14.5%+21.4%
Q4 2017-10.8%-13.9%-2.8%
Q3 2017+6.7%+2.2%-43.1%
Q2 2017-5.6%-11.2%+3.1%
Q1 2017-3.0%-7.7%-16.6%
Q4 2016-1.7%-9.2%+8.3%
Q3 2016+9.3%+6.6%+39.7%
Q2 2016+7.3%+12.8%+18.1%
Q1 2016+3.3%
Q4 2015-3.3%
Q3 2015+13.3%
Q2 2015-17.7%
Q1 2015-15.7%
Q4 2014+21.4%
Q3 2014-1.0%
Q2 2014-1.2%
Q1 2014-9.5%
Q4 2013+0.5%
Q3 2013+0.0%
Q2 2013-7.2%
Q1 2013-1.6%
Q4 2012-1.0%
Q3 2012-1.6%
Q2 2012+6.3%
Q1 2012-4.0%
Q4 2009+0.8%
Q4 2011+0.8%
Q3 2011+3.5%
Q2 2011-14.0%
Q4 2010-14.0%
Q1 2011+2.9%
Q3 2010-4.0%
Q2 2010-14.3%
Q1 2010+0.7%

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