NASDAQ$CUE

Cue Biopharma Inc · Q4 2024 earnings

Q4 2024 earnings · · After market close · Investor relations

Briefing

Cue Biopharma reported its fourth quarter and full year 2024 financial results, highlighting a decrease in collaboration revenue and a net loss, while focusing on autoimmune programs and strategic partnerships.

Cue Biopharma reported a net loss of $9.496 million for the fourth quarter of 2024, with collaboration revenue at $1.576 million. The company focused on prioritizing autoimmune programs and advancing clinical data from oncology programs to support strategic partnerships.

  • Collaboration revenue for Q4 2024 was $1.576 million, a decrease from $1.821 million in Q4 2023.
  • Net loss for Q4 2024 was $9.496 million, compared to a net loss of $13.434 million in Q4 2023.
  • Research and development expenses decreased to $7.184 million in Q4 2024 from $10.887 million in Q4 2023.
  • The company successfully regained worldwide development and commercialization rights for CUE-401, its lead autoimmune program.

Headline financials

Total Revenue

$1.58M

Previous: $1.82M-13.5%
EPS (adj)

-$0.13

Previous: -$0.28+53.6%
Weighted avg shares outstanding

74.2M

Previous: 47.2M+57.3%
Net Income

-$9.5M

Previous: -$13.4M+29.3%
Operating Income

-$9.63M

Previous: -$13.7M+29.6%

Revenue & EPS history

Cue Biopharma · Revenue · Quarterly

$1.58M

Q4 2024-13.5%vs Q4 2023
Beat estimate in 9 of 13 quarters(69%)
ActualEstimate

Revenue by segment

Cue Biopharma · $5.69M total across 1 segment · Q1 2026

  • Collaboration revenue
    $5.69M

Forward guidance

The company's forward-looking statements indicate a focus on advancing autoimmune programs and leveraging its Immuno-STAT™ platform, particularly CUE-401, for potential disruptive opportunities. They also plan to announce a business update call and webcast soon.

Tailwinds

  • Belief that CUE-401 has potential to transform treatment across a broad spectrum of autoimmune and inflammatory diseases.
  • Potential therapeutic benefits of CUE-501 and the CUE-500 series.
  • Ability to advance its Immuno-STAT™ platform.
  • Implementation of a highly focused strategic business model to exploit platform opportunities.
  • Plans to announce a business update call and webcast within the next couple of weeks.

Headwinds

  • Limited operating history and limited cash.
  • History of losses and current 'going concern' determination due to insufficient capital.
  • Potential setbacks in research and development efforts, including negative or inconclusive preclinical/clinical trial results.
  • Inability to replicate positive results from early-stage trials in later clinical trials.
  • Risk of serious and unexpected drug-related side effects or safety issues in clinical trials.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

-0.1%

Avg return

Earnings day

-1.2%

Avg return

5 days after

+0.7%

Avg return

30 days after

45%

15 / 33 earnings

Positive

+25.2%

Q4 2021

Best reaction

-16.7%

Q3 2024

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026-14.2%-31.0%-17.1%
Q4 2025-0.3%-14.7%+97.1%
Q3 2025-8.5%-13.2%-27.1%
Q2 2025+0.0%+3.7%-6.1%
Q1 2025-3.5%-2.5%-18.6%
Q4 2024+3.3%-2.4%-9.4%
Q3 2024-16.7%-28.0%-37.3%
Q2 2024-6.3%+19.9%-7.1%
Q1 2024-8.9%-18.8%-22.5%
Q4 2023+2.7%-5.4%+3.2%
Q3 2023+14.9%+5.4%+8.1%
Q2 2023-12.3%-14.2%-26.5%
Q1 2023-3.7%-12.4%-23.2%
Q4 2022+7.1%+7.4%+14.2%
Q3 2022+20.4%+2.5%-6.1%
Q2 2022+1.7%-5.7%+3.3%
Q1 2022-11.0%-10.0%-8.5%
Q4 2021+25.2%+27.2%+2.9%
Q3 2021-0.4%+6.4%+4.1%
Q2 2021+7.7%+3.5%+23.1%
Q1 2021-1.4%+2.4%-4.2%
Q4 2020-7.5%-4.5%-14.3%
Q3 2020+11.2%+7.1%+17.3%
Q2 2020+1.3%+2.5%-16.0%
Q1 2020+8.3%+13.3%-4.4%
Q4 2019-15.5%+4.8%+59.8%
Q3 2019-2.0%-1.8%+38.4%
Q2 2019+1.3%+7.5%+6.4%
Q1 2019+0.1%+1.5%-6.7%
Q4 2018+9.7%+23.8%+20.3%
Q3 2018-6.7%-8.8%-16.2%
Q2 2018-0.7%-4.9%+11.3%
Q4 2017+0.5%+1.2%-13.5%
Q2 2017
Q1 2017
Q4 2016
Q3 2016
Q2 2016
Q1 2016

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