NASDAQ$CRDF

Cardiff Oncology Inc · Q4 2020 earnings

Q4 2020 earnings · · Investor relations

Briefing

Cardiff Oncology reported fourth quarter results, highlighted by clinical milestones and a successful capital raise.

Cardiff Oncology announced positive results for Q4 2020, marked by key clinical milestones and a successful $100 million capital raise. The company is advancing its clinical programs, particularly in KRAS-mutated cancers, and expanding its pipeline.

  • Raised approximately $100 million in gross proceeds through a common stock offering.
  • Completed enrollment in the Phase 1b portion of the KRAS-mutated metastatic colorectal cancer (mCRC) trial and initiated Phase 2 segment.
  • Identified a biomarker associated with onvansertib-abiraterone synergy in metastatic castrate-resistant prostate cancer (mCRPC).
  • Presented data at ASH demonstrating the safety and anti-leukemic activity of onvansertib in relapsed/refractory AML.

Headline financials

Total Revenue

$119K

Previous: $93K+28.0%
EPS (adj)

-$0.19

Previous: -$0.51+62.7%
Capital Expenditures

$58.1K

No prior period
Free Cash Flow

-$5.18M

No prior period
Net Income

-$6.6M

No prior period
Operating Income

-$6.5M

No prior period
Gross Profit

-$3.08M

No prior period
Cash & Equivalents

$131M

No prior period
Total Assets

$135M

No prior period
Stock-Based Comp

$944K

No prior period

Revenue & EPS history

Cardiff Oncology · Revenue · Quarterly

$119K

Q4 2020+28%vs Q4 2019
Beat estimate in 6 of 15 quarters(40%)
ActualEstimate

Revenue by segment

Cardiff Oncology · $41K total across 1 segment · Q1 2026

  • Royalties
    $41K

Forward guidance

Cardiff Oncology is poised for a steady cadence of catalysts throughout 2021 and beyond as it continues to advance onvansertib's development across multiple clinical programs.

Tailwinds

  • Advancing clinical development programs for onvansertib.
  • Initiating a Phase 2 trial in pancreatic ductal adenocarcinoma (PDAC) in the first half of the year.
  • Demonstrating broad applicability of onvansertib across KRAS-mutated cancers.
  • Achieving a steady cadence of catalysts throughout 2021 and beyond.
  • Optimized dosing schedule of cohort C shows a greater than two-fold improvement in disease control rate compared to cohorts A and B

Headwinds

  • Clinical trials involve a lengthy and expensive process with an uncertain outcome.
  • Clinical trials may be suspended or discontinued due to unexpected side effects or other safety risks.
  • Dependence on key personnel.
  • Uncertainties of patent protection and litigation.
  • There are no guarantees that future clinical trials will be completed or successful

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 19 quarterly earnings reports · overlaid with Q4 2020

Historical avgQ4 2020

+2.2%

Avg return

Earnings day

+1.9%

Avg return

5 days after

+2.8%

Avg return

30 days after

43%

28 / 65 earnings

Positive

+118.2%

Q4 2010

Best reaction

-21.2%

Q4 2016

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q1 2026+1.8%+3.6%-8.3%
Q4 2025+12.9%+14.1%-8.8%
Q3 2025-3.1%-0.4%-6.2%
Q2 2025-1.3%-24.2%-36.6%
Q1 2025+4.0%+2.5%+37.4%
Q4 2024+4.4%+5.2%-19.0%
Q3 2024-19.2%-17.6%-39.4%
Q2 2024+11.2%+5.1%-1.4%
Q1 2024-16.8%-21.7%-24.8%
Q4 2023+59.9%+100.5%+193.4%
Q3 2023+5.7%+3.8%+20.0%
Q2 2023-5.0%-8.3%-15.6%
Q1 2023+1.1%-4.8%-12.4%
Q4 2022+2.3%+7.6%-4.1%
Q3 2022-4.7%-10.7%+5.4%
Q2 2022+15.0%+30.0%+27.7%
Q1 2022-7.7%-11.9%-0.7%
Q4 2021+7.1%+0.4%-5.6%
Q3 2021-5.1%-3.6%-14.1%
Q2 2021+15.0%+19.4%+51.3%
Q1 2021-5.5%-13.1%-24.5%
Q4 2020+0.6%+8.0%-3.1%
Q3 2020+10.6%+5.8%+26.6%
Q2 2020-14.6%-10.2%-3.4%
Q1 2020+0.8%+6.7%+167.5%
Q4 2019-2.8%+12.8%-24.1%
Q3 2019+1.8%+2.4%-20.8%
Q2 2019-4.1%-10.0%+10.6%
Q1 2019-8.1%-11.2%-11.2%
Q4 2018+25.2%+47.0%+18.2%
Q3 2018+6.7%+4.0%-6.7%
Q2 2018-1.2%-1.2%+0.0%
Q1 2018+0.0%-3.6%-47.3%
Q4 2017-6.2%-3.1%+6.2%
Q3 2017-1.5%-4.4%-26.5%
Q2 2017-7.1%+1.2%-13.1%
Q1 2017-5.0%-1.2%+1.3%
Q4 2016-21.2%-28.5%-37.0%
Q3 2016-5.6%-15.5%-29.6%
Q2 2016-6.6%-0.4%-11.0%
Q1 2016-3.7%
Q4 2015-18.7%
Q3 2015+11.7%
Q2 2015-15.0%
Q1 2015+9.6%
Q4 2014+0.3%
Q3 2014-1.9%
Q2 2014+1.6%
Q1 2014-2.3%
Q4 2013+7.9%
Q3 2013+12.2%
Q2 2013-1.7%
Q4 2012-2.4%
Q1 2013-2.4%
Q3 2012+2.3%
Q2 2012-6.5%
Q1 2012+8.8%
Q4 2011-3.9%
Q3 2011-17.1%
Q2 2011+0.0%
Q1 2011+0.0%
Q4 2010+118.2%
Q3 2010+0.0%
Q2 2010+0.0%
Q1 2010+13.2%

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