NASDAQ$CHRS
Coherus Biosciences Inc · Q4 2025 earnings
Q4 2025 earnings · · After market close · Investor relations
Briefing
Revenue increased year over year while the company continued to report significant operating losses as it invested in its oncology pipeline.
Coherus reported higher Q4 revenue driven by LOQTORZI growth, but operating losses remained large as R&D spending increased. The company continues transitioning toward an oncology-focused pipeline while reducing debt and maintaining a sizable cash position.
- Q4 revenue rose year over year driven primarily by LOQTORZI sales growth.
- Operating loss remained significant due to continued R&D investment.
- LOQTORZI revenue grew strongly as adoption expanded in nasopharyngeal carcinoma.
- The company ended the year with over $172 million in cash, cash equivalents and marketable securities.
Headline financials
Revenue & EPS history
Coherus · Revenue · Quarterly
$12.7M
Forward guidance
Management emphasized continued commercialization of LOQTORZI, advancement of oncology pipeline programs, and upcoming clinical data readouts expected in 2026.
Tailwinds
- LOQTORZI adoption continues to expand with strong revenue growth.
- Multiple clinical programs advancing with expected readouts in 2026.
- Substantial reduction in company debt over the past two years.
- Strong cash position to support development programs.
- Potential partnership and combination therapy opportunities across the pipeline.
Headwinds
- The company continues to generate significant operating losses.
- High R&D spending required to advance multiple oncology programs.
- Revenue remains concentrated in a single commercial product.
- Future funding needs may depend on capital markets or partnerships.
- Clinical development timelines and outcomes remain uncertain.
Historical earnings impact
How earnings announcements have historically affected this stock's price.
Avg. return before/after earnings
Based on 19 quarterly earnings reports · overlaid with Q4 2025
+0.3%
Avg return
Earnings day
-2.2%
Avg return
5 days after
+0.4%
Avg return
30 days after
53%
23 / 43 earnings
Positive
+28.8%
Q4 2017
Best reaction
-31.6%
Q3 2023
Worst reaction
| Quarter | Report date | Reaction (Day 0) | +5 days | +30 days |
|---|---|---|---|---|
| Q1 2026 | +10.9% | -10.3% | — | |
| Q4 2025 | +1.6% | -15.5% | -14.5% | |
| Q3 2025 | -9.6% | -8.7% | -19.5% | |
| Q1 2025 | -18.7% | -25.4% | -22.5% | |
| Q4 2024 | +1.0% | -11.5% | -28.7% | |
| Q3 2024 | +12.2% | +6.6% | +132.6% | |
| Q2 2024 | +15.3% | +16.1% | +0.0% | |
| Q1 2024 | -14.8% | -6.7% | -24.2% | |
| Q4 2023 | -3.1% | -0.9% | -0.4% | |
| Q3 2023 | -31.6% | -56.0% | -36.6% | |
| Q2 2023 | +13.8% | +11.8% | +21.4% | |
| Q1 2023 | -19.9% | -33.6% | -27.1% | |
| Q4 2022 | +3.4% | -14.0% | +8.8% | |
| Q3 2022 | -10.4% | -0.4% | -12.7% | |
| Q2 2022 | +17.6% | +9.9% | +1.4% | |
| Q1 2022 | -13.3% | -12.3% | -22.1% | |
| Q4 2021 | -6.5% | -15.6% | +1.0% | |
| Q3 2021 | +4.9% | +4.5% | +1.9% | |
| Q2 2021 | +1.8% | +3.2% | +22.8% | |
| Q1 2021 | -1.6% | -3.2% | -8.8% | |
| Q4 2020 | -6.1% | -1.4% | -10.5% | |
| Q3 2020 | -7.6% | +2.3% | +4.9% | |
| Q2 2020 | +8.0% | +3.2% | +1.4% | |
| Q1 2020 | +6.9% | +4.9% | +16.2% | |
| Q4 2019 | -5.1% | -4.0% | -20.2% | |
| Q3 2019 | +16.4% | +15.1% | +11.1% | |
| Q2 2019 | +19.0% | +15.2% | +31.9% | |
| Q1 2019 | +8.4% | +4.7% | +11.1% | |
| Q4 2018 | +2.4% | +2.6% | -2.8% | |
| Q3 2018 | -19.4% | -10.7% | -16.3% | |
| Q2 2018 | +2.5% | +2.5% | +2.7% | |
| Q1 2018 | +5.8% | +4.5% | +1.8% | |
| Q4 2017 | +28.8% | +35.3% | +23.9% | |
| Q3 2017 | -6.9% | -15.9% | -29.7% | |
| Q2 2017 | +6.3% | -8.3% | +13.4% | |
| Q1 2017 | -1.5% | +13.2% | +4.6% | |
| Q4 2016 | -5.4% | -0.9% | -19.6% | |
| Q3 2016 | +15.7% | +16.1% | +16.6% | |
| Q2 2016 | -3.3% | -1.8% | +1.8% | |
| Q1 2016 | -6.3% | — | — | |
| Q4 2015 | +4.1% | — | — | |
| Q3 2015 | +0.5% | — | — | |
| Q3 2014 | -3.5% | — | — | |
| Q1 2014 | — | — | — | |
| Q4 2013 | — | — | — | |
| Q3 2013 | — | — | — | |
| Q2 2013 | — | — | — | |
| Q1 2013 | — | — | — |
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