NASDAQ$CARM

Carisma Therapeutics Inc · Q4 2024 earnings

Q4 2024 earnings · · Before market open · Investor relations

Briefing

Carisma Therapeutics reported a net loss of $60.477 million and collaboration revenues of $19.632 million for Q4 2024.

Carisma Therapeutics experienced a net loss of $60.477 million in Q4 2024, an improvement from the $86.879 million loss in the prior year. Collaboration revenues increased to $19.632 million, driven by a development candidate nomination. The company implemented significant workforce reductions and ceased development of certain product candidates as part of its cash preservation plan, leading to decreased operating expenses.

  • Net loss improved to $60.477 million in 2024 from $86.879 million in 2023.
  • Collaboration revenues increased to $19.632 million in 2024 from $14.919 million in 2023, primarily due to a development candidate nomination.
  • Research and development expenses decreased by $14.452 million, reflecting a shift in strategic focus and workforce reductions.
  • The company implemented significant cost-reduction initiatives, including a 58% workforce reduction in 2024, and further reductions in March 2025 as part of a cash preservation plan.

Headline financials

Total Revenue

$19.6M

Previous: $4.29M+357.7%
EPS (adj)

-$1.46

Previous: -$0.52-180.8%
Research and Development Expenses

$59.7M

No prior period
General and Administrative Expenses

$22.1M

No prior period
Total Operating Expenses

$81.8M

No prior period
Operating Loss

-$62.2M

No prior period
Interest Income, Net

$1.7M

No prior period
Weighted-Average Shares Outstanding

41.5M

No prior period
Total Liabilities

$58.4M

No prior period
Total Stockholders' Deficit

-$27.9M

No prior period
Operating Lease Commitments

$1.81M

No prior period
Finance Lease Commitments

$963K

No prior period
Net Income

-$60.5M

Previous: -$21M-188.6%
Operating Income

-$62.2M

Previous: -$22.5M-177.0%
Cash & Equivalents

$17.9M

No prior period
Total Assets

$30.5M

No prior period

Revenue & EPS history

Carisma Therapeutics · Revenue · Quarterly

$19.6M

Q4 2024+357.7%vs Q4 2023
Beat estimate in 7 of 12 quarters(58%)
ActualEstimate

Revenue by segment

Carisma Therapeutics · $19.6M total across 1 segment · Q4 2024

  • Collaboration Revenues
    $19.6M

Forward guidance

Carisma Therapeutics is currently focused on identifying and exploring strategic alternatives to maximize value and prepare for an orderly wind-down of operations, with no current intention of resuming research and development activities independently.

Tailwinds

  • The company is exploring a range of strategic alternatives, including sale, license, monetization, or divestiture of assets.
  • The company aims to maximize the value of its assets, including CT-2401, CT-1119, and CAR-M platforms.
  • Potential to realize value from milestone and royalty payments under the Moderna collaboration.
  • The company has reduced operations to preserve existing cash resources.
  • The company has retained employees deemed necessary to pursue strategic alternatives and execute an orderly wind down.

Headwinds

  • There is no assurance that the strategic review process will result in any type of transaction or realization of value for the company or stockholders.
  • It is highly unlikely that there will be cash available for distribution to stockholders if a strategic alternative is not successfully identified or consummated.
  • The company expects to continue to incur significant expenses and operating losses while exploring strategic alternatives and winding down operations.
  • The company's current cash and cash equivalents are not expected to support operations for more than one year following the report date, raising substantial doubt about its ability to continue as a going concern.
  • Any future resumption of research and development activities is dependent on completing a strategic transaction or obtaining significant additional funding, which may not be available on acceptable terms.

Historical earnings impact

How earnings announcements have historically affected this stock's price.

Avg. return before/after earnings

Based on 12 quarterly earnings reports · overlaid with Q4 2024

Historical avgQ4 2024

+0.9%

Avg return

Earnings day

+0.6%

Avg return

5 days after

+6.2%

Avg return

30 days after

54%

26 / 48 earnings

Positive

+32.8%

Q2 2016

Best reaction

-29.2%

Q4 2019

Worst reaction

Earnings price reactions
QuarterReport dateReaction (Day 0)+5 days+30 days
Q4 2025+6.2%+10.1%-98.0%
Q3 2025+2.4%+27.8%+22.6%
Q2 2025-11.8%-8.6%+31.7%
Q1 2025+3.1%-1.4%+153.1%
Q4 2024+11.5%+5.7%-5.6%
Q3 2024-9.0%-10.4%-28.0%
Q2 2024+10.7%+26.2%+25.0%
Q1 2024-4.5%-5.8%-30.3%
Q4 2023-11.5%-19.8%-28.2%
Q3 2023-19.5%-11.1%-15.4%
Q2 2023+12.9%+22.4%-12.9%
Q1 2023-12.3%-17.7%+4.1%
Q4 2022+1.2%-9.6%+62.9%
Q3 2022+0.5%
Q2 2022-3.6%
Q1 2022-1.3%
Q4 2021-2.5%
Q3 2021+3.4%
Q2 2021-8.8%
Q1 2021+5.4%
Q4 2020+5.6%
Q3 2020+3.9%
Q2 2020+7.0%
Q1 2020+1.6%
Q4 2019-29.2%
Q3 2019+0.9%
Q2 2019+1.7%
Q1 2019-2.9%
Q4 2018+0.0%
Q3 2018-7.0%
Q2 2018+2.1%
Q1 2018+17.1%
Q4 2017+19.0%
Q3 2017+2.8%
Q2 2017-12.4%
Q1 2017-2.7%
Q4 2016+13.7%
Q3 2016-4.2%
Q2 2016+32.8%
Q1 2016+6.1%
Q4 2015-8.6%
Q3 2015-0.7%
Q2 2015+15.2%
Q1 2015+17.9%
Q4 2014-2.4%
Q3 2014-2.1%
Q2 2014-3.9%
Q1 2014+1.1%
Q4 2013
Q3 2013
Q2 2013
Q1 2013
Q4 2012

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